Abstract: A system and method for sampling a flight envelope of an air vehicle under test. The method includes obtaining engineering models of the vehicle to identify how the vehicle behaves, obtaining empirical models through test data, and obtaining historical models of similar legacy aircraft. The method further includes ensembling the models into an integrated model and assessing the ensemble uncertainty at any particular test point, for a variety of aircraft conditions, to determine model reliability. The method includes determining the optimal order of test points based on local model uncertainty, testing the air vehicle at a point, revising the integrated model with that data and reassessing the uncertainty, and determining if a stop testing condition has been met, in which case the testing series is closed. The last calibrated integrated model could then be used to generate trusted data for any remaining required test using a certification by analysis method.

Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.

Abstract: Compositions and blends of biopolymers and copolymers are described, along with their use to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries.

Abstract: Compositions and blends of biopolymers and copolymers are described, along with their use to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries.

Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.

Abstract: A welding hand support device of the present disclosure has a body that has a first base and a second base. The body has a first opening on one side and on an opposing side has a second opening. Further, the welding hand support device has a channel formed in the body traversing the body from the first opening to the second opening, the channel configured to receive a welding device.

Abstract: A method of making a microfiber implant. The method uses a fabrication apparatus that comprises a winding platform and a feeder head. The method comprises advancing a microfilament out of the feeder head towards the winding platform and making repeated windings of microfilament around the winding platform. While making the windings, the feeder head moves laterally relative to the winding platform. The feeder head could make multiple sweeps to stack layers of windings. This results in a microfiber patch that can then undergo further processing (e.g. applying a collagen coating) to result in the microfiber implant. Also disclosed are microfiber implants made by this winding technique and apparatus for performing the windings.

Abstract: A soft tissue augmentation implant for surgically reinforcing soft tissue, such as a rotator cuff tendon in the shoulder. The implant comprises one or more slots for passing a suture through the implant. In a two-slot design, the suture may pass through the slots in a buckle configuration. The suture secures the implant to the target soft tissue. The bottom side of the implant has a rough surface or has one or protrusions. This feature facilitates mechanical integration of the implant to the target soft tissue. Also disclosed are soft tissue augmentation assemblies, surgical kits, and methods for reinforcing soft tissue (such as rotator cuff repair).

Abstract: An enclosure device is disclosed for delivering an implantable sheet-like support or repair device, such as ligament, tendon or other soft tissue support or repair device, to a surgical site. The enclosure device protects the support or repair device from unwanted adhesion and deformation during delivery and facilitates its optimal positioning at the injury or repair site where the support or repair device will be implanted. The enclosure device has a planar body foldable along one or more fold lines into at least two panels configured to contain the repair device between the panels; an optional cutout in one or more panels of the planar body at the panel edge opposite the fold line configured to expose a portion of the repair device; an optional positioning tab extending out from the fold line; and an optional securing mechanism to secure the enclosure device in a folded position. Methods of using the enclosure device are described.

Abstract: The invention relates to placenta-derived matrix, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells, delivering cells, promoting differentiation of stem cells or tissue-specific progenitor cells, and repairing, replacing, regenerating, filling, reducing or inhibiting scarring of defects using the same. The invention further relates to methods of coating placenta-derived matrix on a surface or injecting the placenta-derived matrix into a site of interest.

Abstract: The present disclosure relates to compressed bone compositions, bone implants, and variants thereof. The present disclosure also relates to methods of preparing compressed bone compositions, bone implants, and variants thereof. The present disclosure also relates to methods of using the bone compositions, bone implants and variants thereof.

Abstract: The invention relates to placenta-derived matrix, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells, delivering cells, promoting differentiation of stem cells or tissue-specific progenitor cells, and repairing, replacing, regenerating, filling, reducing or inhibiting scarring of defects using the same. The invention further relates to methods of coating placenta-derived matrix on a surface or injecting the placenta-derived matrix into a site of interest.

Abstract: Disclosed are various examples for determining an IT topology for an enterprise IT organization based on operational goals of the enterprise organization. Visual models that are designed to facilitate responses associated with the current IT topology and operational goals of an enterprise IT organization are displayed to an entity of the enterprise. The entity can provide enterprise profile data to an IT solutions system by interacting with user interfaces. The IT solutions system can generate the IT topology prescription and roadmap for implementing the IT topology prescription based on the operational goals identified in the responses. Statements of work can be dynamically generated that outline details and terms of implementing the IT topology prescription for the enterprise IT organization.

Abstract: The present disclosure relates to compressed bone compositions, bone implants, and variants thereof. The present disclosure also relates to methods of preparing compressed bone compositions, bone implants, and variants thereof. The present disclosure also relates to methods of using the bone compositions, bone implants and variants thereof.

Abstract: Disclosed are various examples for determining an IT topology for an enterprise IT organization based on operational goals of the enterprise organization. Visual models that are designed to facilitate responses associated with the current IT topology and operational goals of an enterprise IT organization are displayed to an entity of the enterprise. The entity can provide enterprise profile data to an IT solutions system by interacting with user interfaces. The IT solutions system can generate the IT topology prescription and roadmap for implementing the IT topology prescription based on the operational goals identified in the responses. Statements of work can be dynamically generated that outline details and terms of implementing the IT topology prescription for the enterprise IT organization.

Abstract: Compositions and blends of biopolymers and copolymers are described, along with their use to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries.

Abstract: Compositions and blends of biopolymers and copolymers are described, along with their use to prepare biocompatible scaffolds and surgically implantable devices for use in supporting and facilitating the repair of soft tissue injuries.

Abstract: A scaffold comprising an aligned fiber. Further, a scaffold comprising one or more electrospun fibers wherein a fast Fourier transform (FFT) analysis result of the fibers have adjacent major peaks with about 180° apart from each other. Also, methods for promoting differentiation of stem cells into osteoblasts, chondrocytes, ligament or tendon, the method comprising culturing the cells on the scaffold or aligned fiber in conditions suitable for the cell differentiation.