Patents by Inventor Michael Francis Davitt

Michael Francis Davitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • YAP Inhibition for Wound Healing
    Publication number: 20220313658
    Abstract: Methods of promoting healing of a wound in a dermal location of a subject are provided. Aspects of the methods may include administering an effective amount of a YAP inhibitor composition to the wound to modulate mechanical activation of Engrailed-1 lineage-negative fibroblasts (ENFs) in the wound to promote ENF-mediated healing of the wound. Also provided are methods of preventing scarring during healing of a wound in a subject and methods of promoting hair growth on a subject. Aspects of the methods may include forming a wound in a dermal location of a subject and administering an effective amount of a YAP inhibitor composition to the wound to modulate mechanical activation of Engrailed-1 lineage-negative fibroblasts (ENFs) in the wound to promote ENF-mediated healing of the wound. Also provided are kits including an amount of a YAP inhibitor composition and a tissue disrupting device.
    Type: Application
    Filed: July 24, 2020
    Publication date: October 6, 2022
    Inventors: Shamik Mascharak, Heather Elizabeth DesJardins-Park, Mimi Borrelli, Michael Francis Davitt, Michael T. Longaker