Abstract: An inhalation spacer movable between a collapsed configuration and an expanded configuration. The spacer is made from paperboard having a bending stiffness of at least 2.5 mNm.

Abstract: An aerosol canister for dispensing a product and propellant, and a product metering valve for use with the aerosol canister. The canister includes a high pressure chamber for containing a liquefied or compressed gas propellant, a low pressure chamber for containing a gas propellant, and a product reservoir for containing a gas propellant. A pressure regulating valve is interposed between the high pressure chamber and the low pressure chamber, the pressure regulating valve adapted to provide a fluid flow path from the high pressure chamber to the low pressure chamber when the pressure in the low pressure chamber drops below a predetermined pressure. The canister further includes a partition wall interposed between the low pressure chamber and the product reservoir.

Abstract: An inhalation spacer movable between a collapsed configuration and an expanded configuration. The spacer is made from paperboard having a bending stiffness of at least 2.5 mNm.

Abstract: A canister for a metered dose inhaler has high and low pressure chambers for a propellant and for an inhalable drug and vaporised propellant. The low pressure chamber has an opening for a metering valve. A pressure regulating valve is between the high and low pressure chambers and provides a flow path from them. A metering valve dispenses a metered dose. The valve includes a metering valve body having a propellant metering chamber with a propellant inlet and a product metering chamber with a product inlet, and a metering valve stem with a dispensing nozzle, a propellant inlet plug and a product inlet plug. The metering valve stem moves to a dispensing position. In the dispensing position, the propellant and product metering chambers are in fluid communication with atmosphere via the dispensing nozzle of the metering valve stem such that a metered dose of product and propellant can be dispensed.

Abstract: A tissue graft construct, materials and methods for repairing an injured nerve in a patient. The tissue graft construct includes a band of biocompatible matrix and the hormone prolactin. The graft can be formed into a conduit and used to deliver the hormone prolactin directly at the site of nerve injury to promote healing.

Abstract: An aerosol canister for dispensing a product and propellant, and a product metering valve for use with the aerosol canister. The canister includes a high pressure chamber for containing a liquefied or compressed gas propellant, a low pressure chamber for containing a gas propellant, and a product reservoir for containing a gas propellant. A pressure regulating valve is interposed between the high pressure chamber and the low pressure chamber, the pressure regulating valve adapted to provide a fluid flow path from the high pressure chamber to the low pressure chamber when the pressure in the low pressure chamber drops below a predetermined pressure. The canister further includes a partition wall interposed between the low pressure chamber and the product reservoir.

Abstract: A canister for a metered dose inhaler has high and low pressure chambers for a propellant and for an inhalable drug and vaporised propellant. The low pressure chamber has an opening for a metering valve. A pressure regulating valve is between the high and low pressure chambers and provides a flow path from them. A metering valve dispenses a metered dose. The valve includes a metering valve body having a propellant metering chamber with a propellant inlet and a product metering chamber with a product inlet, and a metering valve stem with a dispensing nozzle, a propellant inlet plug and a product inlet plug. The metering valve stem moves to a dispensing position. In the dispensing position, the propellant and product metering chambers are in fluid communication with atmosphere via the dispensing nozzle of the metering valve stem such that a metered dose of product and propellant can be dispensed.

Abstract: An aqueous dispersion of polymeric particles and process for forming thereof is provided. The particles comprise a first polymer comprising, when dry, at least one void; and, substantially encapsulating the first polymer, at least one second polymer comprising, as polymerized units, at least one ethylenically unsaturated monomer.

Abstract: An aqueous dispersion of polymeric particles, the particles including: from 5% to 80% by weight, based on the weight of the polymeric particles, of a first polymer including at least one copolymerized ethylenically unsaturated monomer; and, substantially encapsulating the first polymer, from 20% to 95% by weight, based on the weight of the polymeric particles, of a second polymer including at least one copolymerized ethylenically unsaturated monomer, the second polymer having a Tg of from ?40° C. to 30° C., wherein at least 90 weight % of the second polymer is formed by polymerization at a temperature of from 5° C. to 65° C. is provided. The invention also relates to a process for forming the aqueous dispersion of polymeric particles and an aqueous coating composition including the aqueous dispersion of polymer particles, a method for providing a coated substrate, and the coated substrate so provided.

Abstract: An aqueous dispersion of polymeric particles and process for forming thereof is provided. The particles comprise a first polymer comprising, when dry, at least one void; and, substantially encapsulating the first polymer, at least one second polymer comprising, as polymerized units, at least one ethylenically unsaturated monomer.

Abstract: An aqueous dispersion of polymeric particles and process for forming thereof is provided. The particles comprise a first polymer comprising, when dry, at least one void; and, substantially encapsulating the first polymer, at least one second polymer comprising, as polymerized units, at least one ethylenically unsaturated monomer.

Abstract: An aqueous dispersion of polymeric particles and process for forming thereof is provided. The particles comprise a first polymer comprising, as polymerized units, at least one monoethylenically unsaturated monomer and at least one multi-ethylenically unsaturated monomer and when dry, at least one void; and at least one second polymer, substantially encapsulating the first polymer, comprising, as polymerized units, at least one ethylenically unsaturated monomer.

Abstract: A paint manufacturing method includes receiving each of a group of fluid prepaints at different inputs of a fluid component mixing system, determining at a computer system a first fluid prepaint ratio, and mixing the fluid prepaints in accordance with the first ratio to form a base paint at an output of the mixing system. A paint manufacturing system includes a computer-controlled prepaint mixing system. The prepaint mixing system includes multiple fluid inputs providing for computer-controllable flow of prepaints into the mixing system. The computer system includes a memory storing software instructions that configured the computer system to receive user input selecting a base paint to be produced, determine a ratio of fluid prepaints needed to produce the base paint, and regulate each fluid flow control to establish, in the determined ratio, a flow of fluid prepaints entering the fluid mixing system.

Abstract: A paint manufacturing method includes receiving each of a group of fluid prepaints at different inputs of a fluid component mixing system, determining at a computer system a first fluid prepaint ratio, and mixing the fluid prepaints in accordance with the first ratio to form a base paint at an output of the mixing system. A paint manufacturing system includes a computer-controlled prepaint mixing system. The prepaint mixing system includes multiple fluid inputs providing for computer-controllable flow of prepaints into the mixing system. The computer system includes a memory storing software instructions that configured the computer system to receive user input selecting a base paint to be produced, determine a ratio of fluid prepaints needed to produce the base paint, and regulate each fluid flow control to establish, in the determined ratio, a flow of fluid prepaints entering the fluid mixing system.

Abstract: An aqueous polymer blend composition including a predominant amount of soft polymer particles and a minor amount of hard polymer particles is provided. The soft polymer particles contain, as copolymerized units, 70 to 99.7% by weight monoethylenically unsaturated (meth)acrylic monomer and from 0.3 to 10% by weight monoethylenically unsaturated acid monomer, based on weight of soft polymer particles. The soft polymer particles are made by a select process including redox polymerization or polymerization in the presence of excess unreacted monomer. The aqueous polymer blend composition is useful for preparing dry coatings having improved dirt pickup resistance and acceptable scrub resistance. A method is provided for preparing a dry coating from the aqueous polymer blend composition.

Abstract: A number of stable mixtures are disclosed containing specific combinations and levels of extender pigments and thickeners. These stable mixtures may be employed, inter alia, as a mixture in a method of making paints using prepaints or as a conventional component in a coating, such as a paint, or other end-use where opacifying pigments are employed.

Abstract: A number of stable opacifying mixtures are disclosed which contain specific combinations and levels of titanium dioxide, thickeners, and dispersants. These stable mixtures may be employed in a method of making paints using prepaints or as a conventional component in a coating such as a paint, or in other end-uses where opacifying pigments are employed.

Abstract: An aqueous tinting composition containing a pigment and a select dispersing resin is disclosed. In addition, a method of improving the viscosity stability of an aqueous coating composition upon the addition of the aqueous tinting composition containing a pigment and a select dispersing resin is disclosed.

Abstract: Sets of fluid premixes useful for adhesives and caulks are provided. Also provided are methods of providing adhesive lines and a caulk lines using the sets of premixes. Further provided are ranges of adhesives and caulks based on the adhesive and caulk lines. Utilizing these methods the manufacturer, seller, or user can to adjust the adhesive or caulk at the point of manufacture, sale, or use to suit the processing and end-use conditions, in addition to the other benefits offered by delayed product differentiation.

Abstract: Sets of prepaints useful for forming a road-marking paint line are provided. Also provided are methods which permit the person applying the road-marking paint to vary the properties of the road-marking paint at the application point to suit the ambient conditions, including temperature, humidity, traffic flow and the like.