Patents by Inventor Michael G. Chaparian

Michael G. Chaparian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4,6-substituted 2,5-dideoxystreptamine aminoglycoside antibiotics
    Patent number: 8586552
    Abstract: Aminoglycoside antibiotics of the formula are disclosed. The compounds are useful for treating bacterial infections, particularly infections resistant to known antibiotics.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: November 19, 2013
    Assignee: SelectX Pharmaceuticals, Inc.
    Inventors: Michael G. Chaparian, Michael Brady, Scott Moe, Babu Rao Renikuntla, Srinivas Gadthula, Srinivasarao Meneni, Venkata Sai Prakash Chaturvedula
  • Methods and targets of antibiotic resistance
    Patent number: 6875582
    Abstract: The present invention provides for a method of evolving and selecting cells resistant to a selective agent by inducing directed evolution in continuous culture while applying both a mutagenic and selective agent to the cells to determine the cells having resistance. This also provides a method of generating mutant drug targets useful for screening for effective compounds.
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: April 5, 2005
    Assignee: OmniScience Pharmaceuticals, Inc.
    Inventors: Michael G. Chaparian, Abul Azad
  • Gene cloning
    Publication number: 20040166526
    Abstract: There is provided a method of targeted cloning of genes and gene clusters by directly isolating the DNA of interest from a mixed population, thereby permitting the construction of a very targeted, highly enriched library. Also provided are several unique methods for cloning the genes provided by this method and the probes used in connection with this method.
    Type: Application
    Filed: March 5, 2004
    Publication date: August 26, 2004
    Inventors: Michael G. Chaparian, Yiping Huang