Patents by Inventor Michael G. Ehrlich

Michael G. Ehrlich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanocarriers and their processing for diagnostics and therapeutics
    Patent number: 12357635
    Abstract: The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: July 15, 2025
    Assignee: Rhode Island Hospital
    Inventors: Qian Chen, Yupeng Chen, Hongchuan Yu, Michael G. Ehrlich
  • NANOCARRIERS AND THEIR PROCESSING FOR DIAGNOSTICS AND THERAPEUTICS
    Publication number: 20200375991
    Abstract: The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.
    Type: Application
    Filed: January 10, 2020
    Publication date: December 3, 2020
    Inventors: Qian Chen, Yupeng Chen, Hongchuan Yu, Michael G. Ehrlich
  • Nanocarriers and their processing for diagnostics and therapeutics
    Patent number: 10555948
    Abstract: The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: February 11, 2020
    Assignee: Rhode Island Hospital
    Inventors: Qian Chen, Yupeng Chen, Hongchuan Yu, Michael G. Ehrlich
  • Nanocarriers And Their Processing For Diagnostics And Therapeutics
    Publication number: 20180193344
    Abstract: The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.
    Type: Application
    Filed: August 25, 2017
    Publication date: July 12, 2018
    Inventors: Qian Chen, Yupeng Chen, Hongchuan Yu, Michael G. Ehrlich
  • Nanocarriers and their processing for diagnostics and therapeutics
    Patent number: 9775842
    Abstract: The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: October 3, 2017
    Assignee: Rhode Island Hospital
    Inventors: Qian Chen, Yupeng Chen, Hongchuan Yu, Michael G. Ehrlich
  • Compositions and Methods for the Prevention and Treatment of Osteolysis and Osteoporosis
    Publication number: 20150352131
    Abstract: This application discloses compositions, devices, and methods for the prevention and treatment of osteolysis and osteoporosis. Treatment or prevention of osteolysis or osteoporosis is carried out by targeting the enzyme, Shp2 (a Src homology 2 (SH2) domain containing non-transmembrane Protein Tyrosine Phosphatase (PTP)), or proteins involved in the Shp2 signaling pathway by administering a Shp2 pathway inhibitor that inhibits fusion of pre-osteoclasts.
    Type: Application
    Filed: January 16, 2014
    Publication date: December 10, 2015
    Applicant: RHODE ISLAND HOSPITAL
    Inventors: Wentian Yang, Michael G. Ehrlich, Yi Zhou, Douglas Moore
  • Nanocarriers And Their Processing For Diagnostics And Therapeutics
    Publication number: 20150258094
    Abstract: The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis.
    Type: Application
    Filed: March 16, 2015
    Publication date: September 17, 2015
    Inventors: Qian Chen, Yupeng Chen, Hongchuan Yu, Michael G. Ehrlich
  • Methods for treatment of distraction osteogenesis using PDGF
    Patent number: 8349796
    Abstract: The present invention relates to compositions and methods for use in osteodistraction procedures. In one embodiment, a method of stimulating osteogenesis during and/or following bone distraction comprises providing a composition comprising a PDGF solution disposed in a biocompatible matrix and applying the composition to at least one site of bone distraction.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: January 8, 2013
    Assignee: BioMimetic Therapeutics Inc.
    Inventors: Samuel E. Lynch, Charles E. Hart, Michael G. Ehrlich, Douglas C. Moore
  • COMPOSITIONS AND METHODS FOR DISTRACTION OSTEOGENESIS
    Publication number: 20110165245
    Abstract: The present invention relates to compositions and methods for use in osteodistraction procedures. In one embodiment, a method of stimulating osteogenesis during and/or following bone distraction comprises providing a composition comprising a PDGF solution disposed in a biocompatible matrix and applying the composition to at least one site of bone distraction.
    Type: Application
    Filed: March 15, 2011
    Publication date: July 7, 2011
    Applicant: BioMimetic Therapeutics, Inc.
    Inventors: Samuel E. LYNCH, Charles E. Hart, Michael G. Ehrlich, Douglas C. Moore
  • Methods for treatment of distraction osteogenesis using PDGF
    Patent number: 7943573
    Abstract: The present invention relates to compositions and methods for use in osteodistraction procedures. In one embodiment, a method of stimulating osteogenesis during and/or following bone distraction comprises providing a composition comprising a PDGF solution disposed in a biocompatible matrix and applying the composition to at least one site of bone distraction.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: May 17, 2011
    Assignee: BioMimetic Therapeutics, Inc.
    Inventors: Samuel E. Lynch, Charles E. Hart, Michael G. Ehrlich, Douglas C. Moore
  • COMPOSITIONS AND METHODS FOR DISTRACTION OSTEOGENESIS
    Publication number: 20090232890
    Abstract: The present invention relates to compositions and methods for use in osteodistraction procedures. In one embodiment, a method of stimulating osteogenesis during and/or following bone distraction comprises providing a composition comprising a PDGF solution disposed in a biocompatible matrix and applying the composition to at least one site of bone distraction.
    Type: Application
    Filed: February 9, 2009
    Publication date: September 17, 2009
    Inventors: Samuel E. Lynch, Charles E. Hart, Michael G. Ehrlich, Douglas C. Moore