Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: Compliance margin of a waveform is determined relative to a standard, indicating the extent to which the waveform either complies or fails to comply with the standard. An acquisition system captures the waveform of an applied signal in a display space, and a memory stores a representation of a series of scaled masks in the display space. Each scaled mask in the series is a version of the standard that is scaled relative to the standard according to a corresponding scale factor. A comparator determines which scaled masks in the series coincide with the waveform at one or more predesignated locations in the display space by comparing the waveform to the represented series of scaled masks at the one or more locations. An output device indicates the compliance margin of the waveform based on the corresponding scale factors of the scaled masks that coincide with the waveform at the one or more locations in the display space.

Abstract: A lightwave component analyzer including at least an internal optical receiver and preferably also including an internal optical source which are selectively connectable by switches configurable by means of an instrument controller for calibration and performance of electro-optical, opto-electrical, and optical measurements. Transmission measurements of E/O devices are corrected for source match errors, and transmission measurements of O/E devices are corrected for load match errors, in addition to frequency response and cross-talk error correction. Response and match error correction provides for improved measurements of test devices with an electrical port having an impedance different from that of the measurement system impedance.

Abstract: A lightwave component measurement system provides modulation measurements and the use of digital signal processing for the resolution of single or multiple optical reflections in optical fiber cable or in open beam at discontinuities attributable to changes in the effective index of refraction in an optical transmission medium. The lightwave component measurement system preferably incorporates a transform capability that converts data measured in the modulation frequency domain to the time or distance domain. The time-domain data are both stable and accurate, since they are calculated from highly-stable, highly-precise frequency-domain information. The time-domain transform capability in the lightwave component measurement system allows a reflection to be located to millimeters, and resolution of multiple discontinuities just centimeters apart.

Abstract: A method and apparatus for calibrating absolute and relative measurements of modulation and/or demodulation transfer characteristics of electro-optical and opto-electrical devices during setup of a lightwave component measurement system for characterizing performance of fiber optic systems and associated components. The lightwave component measurement system calibrated in accordance with the method of the invention provides the capability to measure the optical, electrical, and, especially, the electro-optical (E/O) and opto-electrical (O/E) components with specified measurement performance. In accordance with the calibration method of the invention, when the lightwave component measurement system is used to characterize an E/O or O/E device, an initial calibration reference is established based on the known characteristics of a lightwave source and lightwave receiver included in the lightwave component measurement system.

Abstract: A signal measurement system with softkey menus for guiding a user in selecting a desired test setup, including selection and connection of the device to be tested, as well as selecting calibration measurement and test measurement for the device. In response to a given softkey selection, the signal measurement system prompts the user with a set of displayed textual instructions and pictorial diagrams via a user interface to step the user through setup, calibration, and measurement processes. Preferably, a signal processing unit (or analyzer) included in the signal measurement system incorporates the user interface in firmware to guide and aid the user in connecting the device to be tested to the signal measurement system for the desired test, and leading the user through calibration and measurement processes. The analyzer preferably displays the softkey menus, instructional text displays, and pictorial block diagram displays on a cathode ray tube included in the analyzer to guide the user.

Abstract: A simplified building element which may be remotely prefabricated for use in on-site building construction includes a rafter beam and a support post which are slidably interconnected by a link element and which are capable of being stored and transported to a building site in a collapsed juxtaposition in a generally parallel orientation with one end of the support post being slidable along the length of the rafter beam during on-site construction of a building to raise the rafter beam above the support post while the support post is placed in a vertical orientation.