Abstract: A method of altering corneal tissue includes creating an electrochemical reaction in the tissue, wherein the electrochemical reaction occurs in the presence of an electrolytic solution in or on the tissue.

Abstract: A method of altering adipose tissue includes creating an electrochemical reaction in the tissue, wherein the electrochemical reaction occurs in the presence of an electrolytic solution in the tissue.

Abstract: A method of modifying a tissue includes providing an electrochemical reaction in the tissue by the use of an anodic electrode and a cathodic electrode wherein at least one of the anodic and cathodic electrodes is in contact with the tissue; and setting a concentration of electrochemically generated chemical agents that affect the tissue.

Abstract: A method, system and computer program product are disclosed for providing content to a communications device. In an embodiment of the invention, a communications network receives a first content portion from a content provider and sends the first content portion to the communications device. The communications network also sends a second content portion to the communications device, and this second content portion is customized for the user of the communications device based on selected information about the user that the communications network has. In one embodiment, the communications network uses the selected information about the user to customize the second content portion for the user, and sends the customized second content portion to the communications device. In an embodiment, the communications network sends the selected information to the content provider, and the content provider uses the selected information to customize the second content portion.

Abstract: A two-electrode detection system having target substrates including nucleic acids, proteins, and/or small molecules on specifically defined regions of a single surface. The spatial distribution of the target substrate on the surface allows for more accurate substrate interactions and analysis. Additionally, the detection system of the present invention allows for patterning of different target substrates, thereby affording more accurate analysis of multiple substrate targets.

Abstract: A method of altering adipose tissue includes creating an electrochemical reaction in the tissue, wherein the electrochemical reaction occurs in the presence of an electrolytic solution in the tissue.

Abstract: A method of modifying a tissue includes providing an electrochemical reaction in the tissue by the use of an anodic electrode and a cathodic electrode wherein at least one of the anodic and cathodic electrodes is in contact with the tissue; and setting a concentration of electrochemically generated chemical agents that affect the tissue.

Abstract: The present invention relates to the use of electrochemistry to control and generate specific user defined chemical reactions in regions that may be defined by electrode placement and geometry. In one embodiment, the present invention provides a method of shape changing cartilage in a subject through potential-driven electrochemical modification of tissue (PDEMT) or use of a potential-driven electromechanical (EMR) device.

Abstract: A method, system and computer program product are disclosed for providing content to a communications device. In an embodiment of the invention, a communications network receives a first content portion from a content provider and sends the first content portion to the communications device. The communications network also sends a second content portion to the communications device, and this second content portion is customized for the user of the communications device based on selected information about the user that the communications network has. In one embodiment, the communications network uses the selected information about the user to customize the second content portion for the user, and sends the customized second content portion to the communications device. In an embodiment, the communications network sends the selected information to the content provider, and the content provider uses the selected information to customize the second content portion.

Abstract: A method, system and computer program product are disclosed for providing content to a communications device. In an embodiment of the invention, a communications network receives a first content portion from a content provider and sends the first content portion to the communications device. The communications network also sends a second content portion to the communications device, and this second content portion is customized for the user of the communications device based on selected information about the user that the communications network has. In one embodiment, the communications network uses the selected information about the user to customize the second content portion for the user, and sends the customized second content portion to the communications device. In an embodiment, the communications network sends the selected information to the content provider, and the content provider uses the selected information to customize the second content portion.

Abstract: The present invention relates to the use of electrochemistry to control and generate specific user defined chemical reactions in regions that may be defined by electrode placement and geometry. In one embodiment, the present invention provides a method of shape changing cartilage in a subject through potential-driven electrochemical modification of tissue (PDEMT) or use of a potential-driven electromechanical (EMR) device.

Abstract: A two-electrode detection system having target substrates including nucleic acids, proteins, and/or small molecules on specifically defined regions of a single surface. The spatial distribution of the target substrate on the surface allows for more accurate substrate interactions and analysis. Additionally, the detection system of the present invention allows for patterning of different target substrates, thereby affording more accurate analysis of multiple substrate targets.

Abstract: A method, system and computer program product are disclosed for providing content to a communications device. In an embodiment of the invention, a communications network receives a first content portion from a content provider and sends the first content portion to the communications device. The communications network also sends a second content portion to the communications device, and this second content portion is customized for the user of the communications device based on selected information about the user that the communications network has. In one embodiment, the communications network uses the selected information about the user to customize the second content portion for the user, and sends the customized second content portion to the communications device. In an embodiment, the communications network sends the selected information to the content provider, and the content provider uses the selected information to customize the second content portion.

Abstract: A method, system and computer program product are disclosed for providing content to a communications device. In an embodiment of the invention, a communications network receives a first content portion from a content provider and sends the first content portion to the communications device. The communications network also sends a second content portion to the communications device, and this second content portion is customized for the user of the communications device based on selected information about the user that the communications network has. In one embodiment, the communications network uses the selected information about the user to customize the second content portion for the user, and sends the customized second content portion to the communications device. In an embodiment, the communications network sends the selected information to the content provider, and the content provider uses the selected information to customize the second content portion.

Abstract: A method, system and computer program product are disclosed for providing content to a communications device. In an embodiment of the invention, a communications network receives a first content portion from a content provider and sends the first content portion to the communications device. The communications network also sends a second content portion to the communications device, and this second content portion is customized for the user of the communications device based on selected information about the user that the communications network has. In one embodiment, the communications network uses the selected information about the user to customize the second content portion for the user, and sends the customized second content portion to the communications device. In an embodiment, the communications network sends the selected information to the content provider, and the content provider uses the selected information to customize the second content portion.

Abstract: Compositions and methods for electrochemical detection and localization of genetic point mutations, common DNA lesions and other base-stacking perturbations within oligonucleotide duplexes adsorbed onto electrodes and their use in biosensing technologies are described. An intercalative, redox-active moiety (such as an intercalator or nucleic acid-binding protein) is adhered and/or crosslinked to immobilized DNA duplexes at different separations from an electrode and probed electrochemically in the presence or absence of a non-intercalative, redox-active moiety. Interruptions in DNA-mediated electron-transfer caused by base-stacking perturbations, such as mutations or binding of a protein to its recognition site are reflected in a difference in electrical current, charge and/or potential.

Abstract: Compositions and methods for electrochemical detection and localization of genetic point mutations, common DNA lesions and other base-stacking perturbations within oligonucleotide duplexes adsorbed onto electrodes and their use in biosensing technologies are described. An intercalative, redox-active moiety (such as an intercalator or nucleic acid-binding protein) is adhered and/or crosslinked to immobilized DNA duplexes at different separations from an electrode and probed electrochemically in the presence or absence of a non-intercalative, redox-active moiety. Interruptions in DNA-mediated electron-transfer caused by base-stacking perturbations, such as mutations or binding of a protein to its recognition site are reflected in a difference in electrical current, charge and/or potential.

Abstract: Compositions and methods for electrochemical detection and localization of genetic point mutations, common DNA lesions and other base-stacking perturbations within oligonucleotide duplexes adsorbed onto electrodes and their use in biosensing technologies are described. An intercalative, redox-active moiety (such as an intercalator or nucleic acid-binding protein) is adhered and/or crosslinked to immobilized DNA duplexes at different separations from an electrode and probed electrochemically in the presence or absence of a non-intercalative, redox-active moiety. Interruptions in DNA-mediated electron-transfer caused by base-stacking perturbations, such as mutations or binding of a protein to its recognition site are reflected in a difference in electrical current, charge and/or potential.

Abstract: Compositions and methods for electrochemical detection and localization of genetic point mutations, common DNA lesions and other base-stacking perturbations within oligonucleotide duplexes adsorbed onto electrodes and their use in biosensing technologies are described. An intercalative, redox-active moiety (such as an intercalator or nucleic acid-binding protein) is adhered and/or crosslinked to immobilized DNA duplexes at different separations from an electrode and probed electrochemically in the presence or absence of a non-intercalative, redox-active moiety. Interruptions in DNA-mediated electron-transfer caused by base-stacking perturbations, such as mutations or binding of a protein to its recognition site are reflected in a difference in electrical current, charge and/or potential.

Abstract: Compositions and methods for electrochemical detection and localization of genetic point mutations and other base-stacking perturbations within oligonucleotide duplexes adsorbed onto electrodes and their use in biosensing technologies are described. An intercalative, redox-active moiety (such as an intercalator or nucleic acid-binding protein) is adhered and/or crosslinked to immobilized DNA duplexes at different separations from an electrode and probed electrochemically in the presence or absence of a non-intercalative, redox-active moiety. Interruptions in DNA-mediated electron-transfer caused by base-stacking perturbations, such as mutations or binding of a protein to its recognition site are reflected in a difference in electrical current, charge and/or potential.