Patents by Inventor Michael G. Ikonomou

Michael G. Ikonomou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electrospray interface for mass spectrometer and method of supplying analyte to a mass spectrometer
    Patent number: 5349186
    Abstract: A novel electrospray interface provides high sensitivity and signal stability for mass spectrometric detection of analytes in solvents with high water content including 100% water. The electrospray capillary tip section is heated close to the boiling point of the solvent. An approximately 20.degree. C. hotter airstream is also used. Its flow is coaxial and codirectional to the electrospray. With this arrangement, the analyte signal sensitivity and stability obtained with neat water is equal to that with neat methanol. The charged state (degree of protonation) of protonated peptides sprayed from neat water and the heated spray is essentially identical to that observed with unheated spray where the solvent was 80% methanol-20% water.
    Type: Grant
    Filed: June 25, 1993
    Date of Patent: September 20, 1994
    Assignee: The Governors of the University of Alberta
    Inventors: Michael G. Ikonomou, Paul Kebarle