Patents by Inventor Michael G. Johnson
Michael G. Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8940724Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjogren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110? activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute LymphobType: GrantFiled: June 25, 2010Date of Patent: January 27, 2015Assignee: Amgen Inc.Inventors: Timothy D. Cushing, Paul John Dransfield, Felix Gonzalez Lopez de Turiso, Michael G. Johnson, Todd Kohn, Vatee Pattaropong, Jillian L. Simard
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Patent number: 8938402Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: GrantFiled: June 15, 2012Date of Patent: January 20, 2015Assignee: Lead Core Fund, L.L.C.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Patent number: 8924310Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: GrantFiled: June 15, 2012Date of Patent: December 30, 2014Assignee: Lead Core Fund, L.L.C.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Publication number: 20140315895Abstract: The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.Type: ApplicationFiled: June 26, 2014Publication date: October 23, 2014Inventors: Michael D. Bartberger, Ana Gonzalez Buenrostro, Hilary Plake Beck, Xiaoqi Chen, Richard Victor Connors, Jeffrey Deignan, Jason A. Duquette, John Eksterowicz, Benjamin Fisher, Brian M. Fox, Jiasheng Fu, Zice Fu, Felix Gonzalez Lopez de Turiso, Michael W. Gribble, Darin J. Gustin, Julie A. Heath, Xin Huang, XianYun Jiao, Michael G. Johnson, Frank Kayser, David John Kopecky, SuJen Lai, Yihong Li, Zhihong Li, Jiwen Liu, Jonathan D. Low, Brian S. Lucas, Zhihua MA, Lawrence R. McGee, Joel Mcintosh, Dustin L. McMinn, Julio C. Medina, Jeffrey Thomas Mihalic, Steven H. Olson, Yosup Rew, Philip M. Roveto, Daqing Sun, Xiaodong Wang, Yingcai Wang, Xuelei Yan, Ming Yu, Jiang Zhu
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Publication number: 20140235629Abstract: The present invention provides MDM2 inhibitor compounds of Formula I or II, or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.Type: ApplicationFiled: September 26, 2012Publication date: August 21, 2014Inventors: Michael D. Bartberger, Hilary Plake Beck, Xiaoqi Chen, Richard Victor Connors, Jeffrey Deignan, Jason A. Duquette, John Eksterowicz, Brian M. Fox, Jiasheng Fu, Ana Gonzalez Buenrostro, Felix Gonzalez Lopez De Turiso, Darin J. Gustin, Julie A. Heath, Michael G. Johnson, Frank Kayser, David John Kopecky, Yihong Li, Zhihong Li, Zhihua Ma, Joel Micintosh, Julio C. Medina, Jeffrey Thomas Mihalic, Steven H. Olson, Yosup Rew, Philip M. Roveto, Michael J. Schmitt, Daqing Sun, Xiaodong Wang, Malgorzata Wanska, Christine Weathers, Xuelei Yan
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Patent number: 8404722Abstract: The present invention relates generally to compounds represented in Formula (I), pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.Type: GrantFiled: March 13, 2009Date of Patent: March 26, 2013Assignee: Amgen Inc.Inventors: Matthew Brown, Michael G. Johnson
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Publication number: 20120271771Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: ApplicationFiled: June 15, 2012Publication date: October 25, 2012Applicant: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Publication number: 20120265690Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: ApplicationFiled: June 15, 2012Publication date: October 18, 2012Applicant: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Publication number: 20120259734Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: ApplicationFiled: June 15, 2012Publication date: October 11, 2012Applicant: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Publication number: 20120253978Abstract: A system and method for conducting electronic commerce are disclosed, In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: ApplicationFiled: June 15, 2012Publication date: October 4, 2012Applicant: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Publication number: 20120240227Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: ApplicationFiled: June 4, 2012Publication date: September 20, 2012Applicant: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Publication number: 20120185021Abstract: A heat transfer pad includes a pad inlet port for feeding a heat transfer fluid to the pad, a pad outlet port for discharging the heat transfer fluid from the pad and a bladder having an internal flowpath for the heat transfer fluid which extends from the pad inlet port to the pad outlet port. The internal flowpath is divided into a first flow channel and a second flow channel through which first and second flow streams of the heat transfer fluid, respectively, flow between the pad inlet and outlet ports. A first flow restrictor is positioned downstream in the first flow channel and a second flow restrictor is correspondingly positioned downstream in the second flow channel and the flow restrictors are configured to create substantial back pressures in the first and second flow channels, respectively.Type: ApplicationFiled: January 14, 2011Publication date: July 19, 2012Applicant: BREG, INC.Inventors: Michael G. Johnson, Stefanie L. Mah, James M. Fout, Christian L. Hansen
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Patent number: 8214299Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: GrantFiled: August 18, 2010Date of Patent: July 3, 2012Assignee: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Publication number: 20110319378Abstract: The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.Type: ApplicationFiled: June 3, 2011Publication date: December 29, 2011Applicant: AMGEN INC.Inventors: Michael David BARTBERGER, Ana GONZALEZ BUENROSTRO, Hilary Plake BECK, Xiaoqi CHEN, Richard Victor CONNORS, Jeffrey DEIGNAN, Jason DUQUETTE, John EKSTEROWICZ, Benjamin FISHER, Brian Matthew FOX, Jiasheng FU, Zice FU, Felix GONZALEZ LOPEZ DE TURISO, Michael GRIBBLE, JR., Darin James GUSTIN, Julie Anne HEATH, Xin HUANG, Xianyun JIAO, Michael G. JOHNSON, Frank KAYSER, David John KOPECKY, Sujen LAI, Yihong LI, Zhihong LI, Jiwen LIU, Jonathan Dante LOW, Brian Stuart LUCAS, Zhihua MA, Lawrence McGEE, Joel McINTOSH, Dustin McMINN, Julio Cesar MEDINA, Jeffrey Thomas MIHALIC, Steven Howard Olson, Yosup REW, Philip Marley ROVETO, Daqing SUN, Xiaodong WANG, Yingcai WANG, Xuelei YAN, Ming YU, Jiang ZHU
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Patent number: 7960567Abstract: Compounds, compositions and methods that are useful in the treatment of inflammatory and immune-related diseases and conditions are provided herein. In particular, the invention provides compounds which modulate the function and/or expression of proteins involved in atopic diseases, inflammatory conditions and cancer. The subject compounds are carboxylic acid derivatives.Type: GrantFiled: April 30, 2008Date of Patent: June 14, 2011Assignee: Amgen Inc.Inventors: Matthew Brown, Michael G. Johnson, An-Rong Li, Jiwen Liu, Sarah E. Lively, Julio C. Medina, Wang Shen, Xuemei Wang, Yingcai Wang
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Patent number: 7939538Abstract: Compounds are provided having the formula: wherein variables Ra, R1, R2, R3, R4, A1, A4, L, Q, X and subscript n as described herein. The subject compounds are useful for treatment of inflammatory and immune conditions and diseases. Compositions and methods of treatment using the subject compounds are also provided. For example, the subject methods are useful for treatment of inflammatory and immune disorders and disease such as multiple sclerosis, rheumatoid arthritis, psoriasis, and inflammatory bowel disease.Type: GrantFiled: June 27, 2005Date of Patent: May 10, 2011Assignee: Amgen Inc.Inventors: Zice Fu, Michael G. Johnson, An-Rong Li, Andrew P. Marcus, Julio C. Medina, Philippe Bergeron, Xiaoqi Chen, Xiaohui Du, Jeffrey Deignan, Jason A. Duquette, Darin Gustin, Jeffrey T. Mihalic, Jiwen Liu
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Publication number: 20100331306Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity.Type: ApplicationFiled: June 25, 2010Publication date: December 30, 2010Applicant: AMGEN INC.Inventors: Minna Bui, Yi Chen, Timothy D. Cushing, Jason A. Duquette, BenjamÃn Fisher, Felix Gonzalez Lopez De Turiso, Xiaolin Hao, Xiao He, Michael G. Johnson, Brian Lucas
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Publication number: 20100331293Abstract: Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjogren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110? activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute LymphobType: ApplicationFiled: June 25, 2010Publication date: December 30, 2010Applicant: AMGEN INC.Inventors: Timothy D. Cushing, Paul John Dransfield, Felix Gonzalez Lopez De Turiso, Michael G. Johnson, Todd Kohn, Vatee Pattaropong, Jillian L. Simard
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Publication number: 20100312667Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: ApplicationFiled: August 18, 2010Publication date: December 9, 2010Applicant: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliott Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E. Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B. White, Russell Bennett
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Patent number: 7801827Abstract: A system and method for conducting electronic commerce are disclosed. In various embodiments, the electronic transaction is a purchase transaction. A user is provided with an intelligent token, such as a smartcard containing a digital certificate. The intelligent token suitably authenticates with a server on a network that conducts all or portions of the transaction on behalf of the user. In various embodiments a wallet server interacts with a security server to provide enhanced reliability and confidence in the transaction. In various embodiments, the wallet server includes a toolbar. In various embodiments, the digital wallet pre-fills forms. Forms may be pre-filled using an auto-remember component.Type: GrantFiled: April 9, 2004Date of Patent: September 21, 2010Assignee: American Express Travel Related Services Company, Inc.Inventors: Fred Alan Bishop, Elliot Harold Glazer, Zygmunt Steven Gorgol, William G. Hohle, Michael G. Johnson, David E Johnstone, Walter Donald Lake, Coby Royer, Marvin Simkin, Nick Swift, Dirk B White, Russell Bennett