Patents by Inventor Michael G. Smith

Michael G. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190142973
    Abstract: The present invention encompasses engineered nucleases which recognize and cleave a recognition sequence within the int22h-1 sequence of a Factor VIII gene. The present invention also encompasses methods of using such engineered nucleases to make genetically-modified cells, and the use of such cells in a pharmaceutical composition and in methods for treating hemophilia A. Further, the invention encompasses pharmaceutical compositions comprising engineered nuclease proteins, nucleic acids encoding engineered nucleases, or genetically-modified cells of the invention, and the use of such compositions for treating of hemophilia A.
    Type: Application
    Filed: May 3, 2017
    Publication date: May 16, 2019
    Applicant: Precision BioSciences, Inc.
    Inventors: Derek Jantz, James Jefferson Smith, Victor Bartsevich, Clayton Beard, Michael G. Nicholson
  • Publication number: 20190005642
    Abstract: An apparatus that senses temperature from a digital infrared sensor is described. A digital signal representing a temperature without conversion from analog is transmitted from the digital infrared sensor received by a microprocessor and converted to body core temperature by the microprocessor.
    Type: Application
    Filed: September 10, 2018
    Publication date: January 3, 2019
    Applicant: ARC Devices, LTD
    Inventors: Martin Crawley, Michael G. Smith, Irwin Gross, Mark Khachaturian, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull
  • Publication number: 20180214198
    Abstract: An electrosurgical device is provided. The device includes a cooled probe, an introducer, and a side port for the introduction of liquid into a lumen defined by an outer diameter of the probe and an inner diameter of the introducer when the probe is positioned inside the introducer such that a distal end of the probe can contact a target site (e.g., the site near/adjacent the tissue to be treated). The side port can be connected to a syringe/other liquid introduction apparatus via tubing so that a liquid (e.g., a therapeutic agent, saline, etc.) can be injected into the lumen and can exit the distal region of the introducer so that it is delivered to the target site. Additionally, the syringe can be removed so that the tubing can serve as a vent during treatment with the electrosurgical device.
    Type: Application
    Filed: August 28, 2015
    Publication date: August 2, 2018
    Inventors: Joseph DiPietro, Michael G. Smith
  • Patent number: 9974438
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: May 22, 2018
    Assignee: Arc Devices, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9931035
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: April 3, 2018
    Assignee: Arc Devices, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9895062
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: February 20, 2018
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9895061
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 28, 2014
    Date of Patent: February 20, 2018
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9888849
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: February 13, 2018
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9888852
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: February 13, 2018
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9888850
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: February 13, 2018
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9888851
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: February 13, 2018
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9881369
    Abstract: A smartphone that includes a microprocessor, a battery operably coupled to the microprocessor, a single button operably coupled to the microprocessor, a communication subsystem that receives messages from and sends messages to wireless networks in accordance with Code Division Multiple Access (CDMA), a digital infrared sensor operably coupled to the microprocessor, the digital infrared sensor having ports that provide a digital signal representing a temperature, and a display device operably coupled to the microprocessor, wherein the microprocessor receives from the ports the digital signal that is representative of the temperature and the microprocessor generates a body core temperature from the digital signal that is representative of the temperature and the microprocessor also operably coupled to the display device displays the body core temperature.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: January 30, 2018
    Assignee: ARC Devices Ltd.
    Inventors: Martin Crawley, Michael G. Smith, Irwin Gross, Mark Khachaturian, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull
  • Patent number: 9872620
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: January 23, 2018
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9801543
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: October 31, 2017
    Assignee: Arc Devices, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9795297
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: October 24, 2017
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9788723
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: October 17, 2017
    Assignee: Arc Devices, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9782074
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: October 10, 2017
    Assignee: Arc Devices, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9782073
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: October 10, 2017
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9775518
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: October 3, 2017
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick
  • Patent number: 9775517
    Abstract: In one implementation, an apparatus estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point is described, estimates temperature from a digital infrared sensor and determines vital signs from a solid-state image transducer, or determines vital signs from a solid-state image transducer and estimates body core temperature from an infrared measurement of an external source point using a cubic relationship between the body core temperature and the measurement of an external source point; after which the estimated and/or determined information is transmitted to an external database.
    Type: Grant
    Filed: December 29, 2014
    Date of Patent: October 3, 2017
    Assignee: ARC DEVICES, LTD
    Inventors: Irwin Gross, Michael G. Smith, Mark Khachaturian, Martin Crawley, Steven Gerst, John Barrett, Michael Cronin, Derek Turnbull, Jason Bodnick