Patents by Inventor Michael G Wyllie

Michael G Wyllie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topical Composition Method for Treating Urinary Stress Incontinence
    Publication number: 20100239670
    Abstract: There is provided a method and composition for treating urinary stress incontinence based upon the topical administration of an alpha-adrenoceptor agonist, such as phenylephrine. A daily dosage of 20 mg to 2000 mg is suitable, and the composition may conveniently be applied as a cream or gel to the vaginal or peri-urethral area.
    Type: Application
    Filed: March 25, 2010
    Publication date: September 23, 2010
    Applicant: Plethora Solutions Ltd.
    Inventors: Michael G Wyllie, Brian Leaker
  • Pharmaceutical combinations
    Patent number: 7138405
    Abstract: Pharmaceutical combinations suitable for treating the lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in men are described herein. The combinations contain an alpha-adrenoceptor antagonist and a muscarinic antagonist that may be administered simultaneously, separately or sequentially. The methods of treatment using the combinations are particularly suitable for treating moderate or severe LUTS.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: November 21, 2006
    Assignee: Novartis International Pharmaceutical Ltd
    Inventor: Michael G Wyllie
  • Topical composition and method for treating urinary stress incontinence
    Publication number: 20040044082
    Abstract: There is provided a method and composition for treating urinary stress incontinence based upon the topical administration of an alpha-adrenoceptor agonist, such as phenylephrine. A daily dosage of 20 mg to 2000 mg is suitable, and the composition may conveniently be applied as a cream or gel to the vaginal or peri-urethral area.
    Type: Application
    Filed: September 29, 2003
    Publication date: March 4, 2004
    Inventor: Michael G. Wyllie
  • Use of alpha1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
    Publication number: 20030125335
    Abstract: A method for treating or preventing a BPH in a mammal which comprises administering to said mammal an amount of a drug, comprising an &agr;1-adrenoreceptor antagonist or pharmaceutically acceptable acid addition salt thereof, effective for treating or preventing the BPH.
    Type: Application
    Filed: February 18, 2003
    Publication date: July 3, 2003
    Applicant: Pfizer Inc.
    Inventors: Timothy C. Thompson, Guang Yang, Michael G. Wyllie
  • Combination effective for the treatment of impotence
    Publication number: 20030040514
    Abstract: This invention relates to the treatment of erectile dysfunction with a combination of (1) a compound selected from &agr;-adrenergic receptor antagonists, and (2) a compound selected from agents which elevate cGMP levels. Sildenafil or a pharmaceutically acceptable salt thereof is preferred as the cGMP PDE elevator. Also included are compositions and kits comprising such impotence treating compounds.
    Type: Application
    Filed: September 25, 2002
    Publication date: February 27, 2003
    Inventor: Michael G. Wyllie
  • Pharmaceutical combinations
    Publication number: 20010044438
    Abstract: Pharmaceutical combinations suitable for treating the lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in men are described herein. The combinations contain an alpha-adrenoceptor antagonist and a muscarinic antagonist that may be administered simultaneously, separately or sequentially. The methods of treatment using the combinations are particularly suitable for treating moderate or severe LUTS.
    Type: Application
    Filed: February 7, 2001
    Publication date: November 22, 2001
    Inventor: Michael G. Wyllie
  • Use of &agr;1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
    Patent number: 6177430
    Abstract: A method for reducing the extent of or preventing further hyperplasia in BPH in a mammal which comprises administering to said mammal an effective amount of a drug comprising an &agr;1-adrenoreceptor antagonist or pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: January 23, 2001
    Assignee: Pfizer Inc
    Inventors: Timothy C Thompson, Guang Yang, Michael G Wyllie
  • Use of .alpha..sub.1 -adrenoreceptor antagonists in the prevention and treatment of cancer
    Patent number: 5935962
    Abstract: A method for treating or preventing a cancer in a mammal which comprises administering to said mammal an amount of a drug, comprising an .alpha..sub.1 -adrenoreceptor antagonist or pharmaceutically acceptable acid addition salt thereof, effective for treating or preventing the cancer.
    Type: Grant
    Filed: March 27, 1997
    Date of Patent: August 10, 1999
    Assignee: Baylor College of Medicine and Pfizer, Inc.
    Inventors: Timothy C. Thompson, Guang Yang, Michael G. Wyllie
  • Method of treating impotence
    Patent number: 5270323
    Abstract: A method of relieving erectile impotence in a human male. The method comprises administering to the male an erectile impotence relieving amount of a compound selected from the group consisting of U.K. 52,046, Amlodipine, Doxazosin and the pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: March 11, 1993
    Date of Patent: December 14, 1993
    Assignee: Pfizer Inc.
    Inventors: George M. Milne, Jr., Michael G. Wyllie
  • Method for prevention of hypertension
    Patent number: 4701462
    Abstract: This invention provides a method for preventing the development of hypertension in a non-hypertension animal, including a human, having an elevated natriuretic hormone level, which comprises administering to said animal an amount of indoramin or a pharmaceutically acceptable salt thereof effective to lower the natriuretic hormone level.
    Type: Grant
    Filed: March 31, 1986
    Date of Patent: October 20, 1987
    Assignee: John Wyeth and Brother Limited
    Inventor: Michael G. Wyllie
  • Anti-obesity agents
    Patent number: 4451465
    Abstract: 2,3,4,10-Tetrahydro-3,3-dimethyl-10-phenylpyrimido[1,2-a]indol-10-ol and the pharmaceutically acceptable acid addition salts thereof are useful in treatment or preventing obesity in mammals. The compounds may be administered in pharmaceutical compositions, optionally with one or more vitamins.
    Type: Grant
    Filed: June 22, 1982
    Date of Patent: May 29, 1984
    Assignee: John Wyeth & Brother Ltd.
    Inventors: Alan C. White, Michael G. Wyllie
  • Method for treatment of cerebrovascular disorders
    Patent number: 4428954
    Abstract: Treating cerebrovascular disorders characterized by poor oxygenation with 3-[2-C benzamide-1-piperidyl) ethyl] indole.
    Type: Grant
    Filed: May 10, 1982
    Date of Patent: January 31, 1984
    Assignee: John Wyeth and Brother Limited
    Inventors: John F. Cavalla, Michael G. Wyllie
  • Xanthine derivatives useful as antidepressives
    Patent number: 4406903
    Abstract: Xanthine derivatives are provided which exhibit psychotropic activity in that they inhibit 5-hydroxytryptamine reuptake in vitro and are indicated for antidepressive use.
    Type: Grant
    Filed: January 12, 1982
    Date of Patent: September 27, 1983
    Assignee: John Wyeth and Brother Limited
    Inventors: Terence J. Ward, Martyn D. Wood, Michael G. Wyllie