Abstract: The invention discloses a method for testing of transport and/or efficacy of chemicals and drugs by assessment of plurality of time-invariant parameters in a relevant environment, leading to higher confidence, predictive capacity and better risks assessment. The method makes use of pre-selected models obsolete as the combination of invariants is sufficient to understand the pharmacokinetics in many cases to predict the drug behavior. With this, the amount of in vivo or clinical tests required could be reduced with substantial savings of time and efforts. It is of a particular importance for the cases where such clinical tests are impossible or unethical to be performed, like on pregnant women due to risks to maternal and fetal health. Also, optimization of drugs design and their distribution satisfying biomedical requirements will be achieved with less time and costs, without explicit knowledge of its pharmacokinetics, mode or mechanism of action.

Abstract: The invention discloses a method for testing of injectable biomaterials and their performance in the treated materials, to obtain functional properties of the biomaterials and of the specimen injected with that biomaterial. The purpose of the method is to measure these properties during injection of a biomaterial into a target object, then measure the properties of a target object specimen after the injection, and then combine these results using material model-free data processing with possible prediction.

Abstract: The invention discloses a method for in vitro testing of specimens, such as biomaterials, to obtain history-dependent, time-invariant functional materials properties using time-convolution and idempotent analysis. The purpose of the method is to measure these properties using a data processing without limitations of materials models, the properties linearity or material homogeneity.

Abstract: Self-aligned fibrous scaffolds are disclosed. The scaffolds are capable of automechanoinduction of cell cultures and methods to induce authomechanoinduction in cancer cells and stem cells are disclosed as well.

Abstract: The invention discloses a method for testing of injectable biomaterials and their performance in the treated materials, to obtain functional properties of the biomaterials and of the specimen injected with that biomaterial. The purpose of the method is to measure these properties during injection of a biomaterial into a target object, then measure the properties of a target object specimen after the injection, and then combine these results using material model-free data processing with possible prediction.

Abstract: The invention discloses a method for in vitro testing of specimens, such as biomaterials, to obtain history-dependent, time-invariant functional materials properties using time-convolution and idempotent analysis. The purpose of the method is to measure these properties using a data processing without limitations of materials models, the properties linearity or material homogeneity.

Abstract: Self-aligned fibrous scaffolds are disclosed. The scaffolds are capable of automechanoinduction of cell cultures and methods to induce authomechanoinduction in cancer cells and stem cells are disclosed as well.

Abstract: The invention relates to a method for in vitro testing of specimens, such as biomaterials or implants, wherein the method comprises at least immersing at least a part of the test specimen into a liquid media, controlling the liquid media, controlling surrounding environment, providing a predetermined non-destructive force to the specimen, and measuring reactions of the specimen or constituents of the liquid media. Further it relates to an apparatus for in vitro testing.

Abstract: The invention relates to a method for in vitro testing of specimens, such as biomaterials or implants, wherein the method comprises at least immersing at least a part of the test specimen into a liquid media, controlling the liquid media, controlling surrounding environment, providing a predetermined non-destructive force to the specimen, and measuring reactions of the specimen or constituents of the liquid media. Further it relates to an apparatus for in vitro testing.

Abstract: A phase change material (PCM) heat exchanger device comprising heat exchanger cells (1a, 1b) operating on the regenerative countercurrent principle, one or more phase change material (PCM) accumulators (2, 3) provided in the heat exchanger cells and one or more vortex tubes (6, 7, 8). When the directions of the air, gas and liquid flows are cyclically reversed in the apparatus, energy is recovered into the heat exchanger cell and the PCM accumulator, and during the subsequent cycle, the energy is released from the heat exchanger cell and PCM accumulator. While one heat exchanger cell and PCM accumulator is being charged, the other heat exchanger cell and PCM accumulator is simultaneously discharged. Warm air exits a first outlet port while cold air exits a second outlet port of the one or more vortex tubes. The fluid flows heat or cool the heat exchanger cells and associated PCM accumulators.

Abstract: A method for concentrating dilute sulfuric acid involves feeding dilute sulfuric acid through at least two electrolytic cells depolarized by sulfur dioxide, and through a cation conductive membrane separating the cathode and anode sides in the electrolytic cell. Also provided is an apparatus for concentrating sulfuric acid, wherein at least a first electrolytic cell is in fluid communication with a second electrolytic cell, and wherein a cation conductive membrane separates the cathode and anode sides in the electrolytic cells.

Abstract: The invention relates to a method for producing gaseous hydrogen and strong sulphuric acid (97-100 wt-%) simultaneously from sulphur dioxide gas and water. Sulphur dioxide gas stream is divided into two separate sub-streams, the first sub-stream is routed for water decomposition in a partial thermochemical cycle of the hydrogen and sulphuric acid production and the second sub-stream is fed to the oxidation of the sulphur dioxide to sulphur trioxide.

Abstract: The invention relates to a method for producing gaseous hydrogen and strong sulphuric acid (97-100 wt-%) simultaneously from sulphur dioxide gas and water. Sulphur dioxide gas stream is divided into two separate sub-streams, the first sub-stream is routed for water decomposition in a partial thermochemical cycle of the hydrogen and sulphuric acid production and the second sub-stream is fed to the oxidation of the sulphur dioxide to sulphur trioxide.

Abstract: The invention relates to a phase change material (PCM) heat exchanger device comprising heat exchanger cells (1a, 1b) operating on the regenerative countercurrent principle, phase change material (PCM) accumulators (2, 3) provided in the heat exchanger cells and a vortex tube (6, 7, 8). When the directions of the air, gas and liquid flows are cyclically reversed in the apparatus, energy is recovered into the heat exchanger cell and the PCM accumulator, and during the subsequent cycle, the energy is released from the heat exchanger cell and PCM accumulator. While one heat exchanger cell and PCM accumulator is being charged, the other heat exchanger cell and PCM accumulator are simultaneously discharged. The cool/hot flow from the vortex tube is used to enhance/create needed temperature differences.