Abstract: A variable resistance device is adapted to be incorporated in an exercise machine to provide variable resistance. The device has a primary fluid chamber. A rotating mechanism rotates within the primary chamber. The rotation mechanism upon rotation encounters a degree of resistance dependent on the amount of fluid in the primary chamber. A secondary chamber is positioned within or proximate the primary chamber. The secondary chamber achieves and maintains an appropriate amount of the fluid in the primary chamber to provide a selected degree of resistance for the exercise machine. Fluid flows through the primary chamber into the secondary chamber and then back into the primary chamber. Variable control of the flow of fluid serves to establish and maintain the appropriate amount of fluid in the primary chamber required for a certain degree of resistance; and can provide differing degrees of resistance for the exercise machine.

Abstract: An exercise apparatus (1) for selectively exercising an upper or lower body portion. The apparatus includes a crank assembly (3) operatively connected to a resistance device (5) via a transmission means (7). The crank assembly is rotatable about a first axis and the resistance device provides a resistance force opposing the rotational movement of the crank assembly. The crank assembly includes actuating means for enabling the user to impart the rotational movement against the resistance force. The position of the first axis is moveable between at least a first position which facilitates actuation of the actuating means by the user's feet in order to provide lower body exercise and a second position which facilitates actuation of the actuating means by the user's hands in order to provide upper body exercise.

Abstract: The invention concerns novel pharmaceutical compositions capable of comprising micelles containing at least a very lipophilic principle enabling to enhance bioavailability of active principles insoluble in aqueous solvents called MIDDS® (Micellar Improved Drug Delivery Solutions).