Patents by Inventor Michael Gerisch

Michael Gerisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES
    Publication number: 20220324865
    Abstract: The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.
    Type: Application
    Filed: May 10, 2019
    Publication date: October 13, 2022
    Inventors: Steffen MUELLER, Rudolf SCHOHE-LOOP, Nuria ORTEGA HERNANDEZ, Frank SUESSMEIER, Eloisa JIMENEZ NUNEZ, Thomas BRUMBY, Niels LINDNER, Christoph GERDES, Elisabeth POOK, Anja BUCHMUELLER, Fabienne Zdenka GAUGAZ, Dieter LANG, Stefanie ZIMMERMANN, Alexander Helmut Michael EHRMANN, Michael GERISCH, Lutz LEHMANN, Andreas TIMMERMANN, Martina SCHAEFER, Georg SCHMIDT, Karl-Heinz SCHLEMMER, Markus FOLLMANN, Elisabeth KERSTEN, Vivian WANG, Xiang GAO, Yafeng WANG
  • 2-amino-N-[7-methoxy-2, 3-dihydroimidazo-[1,2-c] quinazolin-5-yl] pyrimidine-5-carboxamides
    Patent number: 10844066
    Abstract: This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: November 24, 2020
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Thomas Schwarz, Ningshu Liu, Oliver Politz, Michael Gerisch, Dieter Lang
  • 2-AMINO-N- [7-METHOXY-2, 3-DIHYDROIMIDAZO-[1, 2-C] QUINAZOLIN-5-YL] PYRIMIDINE-5-CARBOXAMIDES
    Publication number: 20190092775
    Abstract: This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: March 1, 2017
    Publication date: March 28, 2019
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Thomas SCHWARZ, Ningshu LIU, Oliver POLITZ, Michael GERISCH, Dieter LANG
  • HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF
    Publication number: 20170313665
    Abstract: The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
    Type: Application
    Filed: October 30, 2015
    Publication date: November 2, 2017
    Inventors: Carsten SCHMECK, Michael GERISCH, Nils GRIEBENOW, Peter KOLKHOF, Florian KÖLLING, Anna ENGELEN, Axel KRETSCHMER, Dieter LANG, Klemens LUSTIG, Thomas MONDRITZKI, Elisabeth POOK, Hartmut BECK, Frank SÜßMEIER, Sonja VOLLMER, Pierre WASNAIRE
  • Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof
    Patent number: 9771352
    Abstract: The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: September 26, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Carsten Schmeck, Michael Gerisch, Nils Griebenow, Peter Kolkhof, Florian Kölling, Anna Engelen, Axel Kretschmer, Dieter Lang, Klemens Lustig, Thomas Mondritzki, Elisabeth Pook, Hartmut Beck, Frank Süβmeier, Sonja Vollmer, Pierre Wasnaire
  • HETEROBICYCLICALLY SUBSTITUTED 4-OXOBUTANE ACID DERIVATIVES AND USE THEREOF
    Publication number: 20170121315
    Abstract: The present application relates to novel heterobicyclically substituted 4-oxobutanoic acid derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of respiratory, pulmonary and cardiovascular disorders.
    Type: Application
    Filed: June 8, 2015
    Publication date: May 4, 2017
    Inventors: Hartmut BECK, Volkhart Min-Jian LI, Yolanda CANCHO GRANDE, Andreas TIMMERMAN, Dirk BROHM, Hannah JÖRIßEN, Pamela BOGNER, Michael GERISCH, Dieter LANG
  • CHIRAL 2,5-DISUBSTITUTED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND USE THEREOF
    Publication number: 20170119776
    Abstract: The present application relates to novel, chiral 2,5-disubstituted cyclopentanecarboxylic acid derivatives, to a method for their preparation, to their use on their own or in combinations for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diseases of the respiratory tracts, the lung and the cardiovascular system.
    Type: Application
    Filed: March 31, 2015
    Publication date: May 4, 2017
    Inventors: Hartmut BECK, Volkhart Min-Jian LI, Andreas TIMMERMANN, Pamela BOGNER, Yolanda CANCHO GRANDE, Dirk BROHM, Michael GERISCH, Hannah JÖRISSEN, Dieter LANG
  • 2,5-DISUBSTITUTED CYCLOPENTANE CARBOXYLIC ACIDS FOR THE TREATMENT OF RESPIRATORY TRACT DISEASES
    Publication number: 20170114049
    Abstract: The present application relates to novel 2,5-disubstituted cyclopentanecarboxylic acid derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory, pulmonary and cardiovascular disorders.
    Type: Application
    Filed: March 31, 2015
    Publication date: April 27, 2017
    Inventors: Hartmut BECK, Volkhart Min-Jian LI, Yolanda CANCHO GRANDE, Andreas TIMMERMANN, Dirk BROHM, Hannah JÖRISSEN, Pamela BOGNER, Michael GERISCH, Dieter LANG
  • 2,5-DISUBSTITUTED CYCLOPENTANECARBOXYLIC ACIDS AND THEIR USE
    Publication number: 20170022171
    Abstract: The present application relates to novel 2,5-disubstituted cyclopentanecarboxylic acid derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of respiratory, pulmonary and cardiovascular disorders.
    Type: Application
    Filed: March 31, 2015
    Publication date: January 26, 2017
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Hartmut BECK, Volkhart Min-Jian LI, Yolanda CANCHO GRANDE, Andreas TIMMERMANN, Dirk BROHM, Hannah JÖRISSEN, Pamela BOGNER, Michael GERISCH, Dieter LANG
  • Substituted benzoxazoles
    Patent number: 9493472
    Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: November 15, 2016
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Swen Allerheiligen, Anja Buchmüller, Karen Engel, Christoph Gerdes, Kersten Matthias Gericke, Michael Gerisch, Stefan Heitmeier, Alexander Hillisch, Tom Kinzel, Philip Lienau, Bernd Riedl, Susanne Röhrig, Martina Victoria Schmidt, Julia Strassburger, Adrian Tersteegen
  • Imidazo-, pyrazolopyrazines and imidazotriazines and their use
    Patent number: 9434731
    Abstract: The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: September 6, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Siegel, Andreas Wilmen, Susanne Röhrig, Niels Svenstrup, Mark Jean Gnoth, Stefan Heitmeier, Ulrich Rester, Adrian Tersteegen, Michael Gerisch
  • SUBSTITUTED BENZOXAZOLES
    Publication number: 20160137647
    Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Application
    Filed: May 30, 2014
    Publication date: May 19, 2016
    Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
  • Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof
    Publication number: 20160122325
    Abstract: The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
    Type: Application
    Filed: November 2, 2015
    Publication date: May 5, 2016
    Inventors: Carsten SCHMECK, Michael GERISCH, Nils GRIEBENOW, Peter KOLKHOF, Florian KOLLING, Anna ENGELEN, Axel KRETSCHMER, Dieter LANG, Klemens LUSTIG, Thomas MONDRITZKI, Elisabeth POOK, Hartmut BECK, Frank SÜßMEIER, Sonja VOLLMER, Pierre WASNAIRE
  • SUBSTITUTED BENZOXAZOLES
    Publication number: 20160108027
    Abstract: The invention relates to substituted benzoxazoles and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Application
    Filed: May 30, 2014
    Publication date: April 21, 2016
    Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
  • TRIAZOLOPYRIDINES AS THROMBIN INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES
    Publication number: 20160108039
    Abstract: The invention relates to substituted triazolopyridines and to processes for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders, preferably of thrombotic or thromboembolic disorders.
    Type: Application
    Filed: June 2, 2014
    Publication date: April 21, 2016
    Inventors: Swen ALLERHEILlGEN, Anja BUCHMÜLLER, Karen ENGEL, Christoph GERDES, Kersten Matthias GERICKE, Michael GERISCH, Stefan HEITMEIER, Alexander HILLlSCH, Tom KINZEL, Philip LIENAU, Bernd RIEDL, Susanne RÖHRIG, Martina Victoria SCHMIDT, Julia STRASSBURGER, Adrian TERSTEEGEN
  • Substituted piperidines
    Publication number: 20150183773
    Abstract: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumour disorders.
    Type: Application
    Filed: March 10, 2015
    Publication date: July 2, 2015
    Inventors: Mario JESKE, Dirk HEIMBACH, Susanne RÖHRIG, Yolanda CANCHO GRANDE, Dirk SCHNEIDER, Ulrich RESTER, Eckhard BENDER, Mark MEININGHAUS, Katja ZIMMERMANN, Dmitry ZUBOV, Anja BUCHMÜLLER, Georges VON DEGENFELD, Christoph GERDES, Michael GERISCH, Mark Jean GNOTH, Kersten Matthias GERICKE
  • Substituted piperidines as Par-1 antagonists
    Patent number: 8987248
    Abstract: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumor disorders.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: March 24, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Mario Jeske, Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Kersten Matthias Gericke
  • IMIDAZO-, PYRAZOLOPYRAZINES AND IMIDAZOTRIAZINES AND THEIR USE
    Publication number: 20130261115
    Abstract: The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
    Type: Application
    Filed: May 30, 2013
    Publication date: October 3, 2013
    Inventors: Stephan SIEGEL, Andreas WILMEN, Susanne RÖHRIG, Niels SVENSTRUP, Mark Jean GNOTH, Stefan HEITMEIER, Ulrich RESTER, Adrian TERSTEEGEN, Michael GERISCH
  • Imidazo-, pyrazolopyrazines and imidazotriazines and their use
    Patent number: 8476267
    Abstract: The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
    Type: Grant
    Filed: June 28, 2008
    Date of Patent: July 2, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Siegel, Andreas Wilmen, Susanne Röhrig, Niels Svenstrup, Mark Jean Gnoth, Stefan Heitmeier, Ulrich Rester, Adrian Tersteegen, Michael Gerisch
  • HETEROARYL-SUBSTITUTED PIPERIDINES
    Publication number: 20120214788
    Abstract: The invention relates to novel heteroaryl-substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular diseases and tumour diseases.
    Type: Application
    Filed: February 20, 2012
    Publication date: August 23, 2012
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Dirk Heimbach, Susanne Röhrig, Dirk Schneider, Ulrich Rester, Eckhard Bender, Mark Meininghaus, Katja Zimmermann, Dmitry Zubov, Anja Buchmüller, Georges Von Degenfeld, Christoph Gerdes, Michael Gerisch, Mark Jean Gnoth, Yolanda Cancho Grande, Mario Jeske, Kersten Matthias Gericke