Abstract: Methods and apparatus for optimizing wireless network performance by incorporating platform configuration and use case information. In one exemplary scheme, a client device provides the wireless network with an indications of impacted operations based on the client device's platform configuration. The wireless network can adjust the radio link to the client device so as to best accommodate the impacted operation. In one embodiment, a client device that includes a 3×3 Wireless Local Area Network (WLAN) (or 4×4, 2×2, etc.) and Bluetooth (BT) module identifies a subset of modulation and coding schemes (MCS) that are preferred for operation. The client device provides the identified subset to the WLAN access point (AP). Responsively, the WLAN AP selects a MCS, such that the client device's overall performance remains at an acceptable level. In another embodiment, the server/client can adjust MCS and/or active antenna chains based on the noise floor (NF) level.

Abstract: A mobile marine service module and method allows for in-water service of marine vessels. The service module permits servicing and repair of a marine vessel without removal from the water. The service module can attach to a marine vessel, against the hull, below the water line. Once in place and sealed against the vessel's hull, water from inside the module can be removed to provide a platform to work on the vessel, such as to provide service to the vessel's outdrive, for example. With the mobile marine service module, the vessel remains afloat during service, with little or no stress on the hull.

Abstract: A video commerce application having a graphical user interface (“GUI”) is described. The GUI includes: a single frame video display area for presenting video content; a floating menu box located within the single frame video display area for providing a consumer with multiple interactive control elements comprising: at least one media navigation tool; a product catalogue tool; an account access tool; and a shopping cart for storing product items selected for purchase by the consumer, wherein selection of a shopping cart tool associated with the shopping cart provides the consumer with a second pop out display within the single frame video display area for completing a transaction to purchase items present in the shopping cart, wherein the transaction does not require the consumer to register for an account with a commerce platform.

Abstract: Methods and apparatus for optimizing wireless network performance by incorporating platform configuration and use case information. In one exemplary scheme, a client device provides the wireless network with an indications of impacted operations based on the client device's platform configuration. The wireless network can adjust the radio link to the client device so as to best accommodate the impacted operation. In one embodiment, a client device that includes a 3×3 Wireless Local Area Network (WLAN) (or 4×4, 2×2, etc.) and Bluetooth (BT) module identifies a subset of modulation and coding schemes (MCS) that are preferred for operation. The client device provides the identified subset to the WLAN access point (AP). Responsively, the WLAN AP selects a MCS, such that the client device's overall performance remains at an acceptable level. In another embodiment, the server/client can adjust MCS and/or active antenna chains based on the noise floor (NF) level.

Abstract: The present invention relates to a method for sensitizing a disease cell expressing the epidermal growth factor receptor (EGFR) to a tyrosine kinase inhibitor selective or specific for EGFR and/or its signalling pathway, the method comprising contacting the cell with a miR-7 miRNA, a precursor or variant thereof, or a miRNA comprising a seed region comprising the sequence GGAAGA.

Abstract: The present invention relates to a method for modulating the expression and/or activity of an epidermal growth factor receptor (EGFR) ligand in a cell or tissue, the method comprising contacting the cell or tissue with a miR-7 miRNA, a pre-cursor or variant thereof, a miRNA comprising a seed region comprising the sequence GGAAGA, or an antagonist of any such miRNA.

Abstract: A mobile marine service module and method allows for in-water service of marine vessels. The service module permits servicing and repair of a marine vessel without removal from the water. The service module can attach to a marine vessel, against the hull, below the water line. Once in place and sealed against the vessel's hull, water from inside the module can be removed to provide a platform to work on the vessel, such as to provide service to the vessel's outdrive, for example. With the mobile marine service module, the vessel remains afloat during service, with little or no stress on the hull.

Abstract: A pillow according has an ornamental display on a top side, a main cushioning portion, and speakers. The ornamental display has speaker holding protrusions that protrude from the pillow and hold the speakers.

Abstract: The invention concerns pyrimidine derivatives of Formula (I) wherein each of p, R1, R2, q, R3, r, R4, X1 and Q1 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the production of an anti-proliferative effect in a warm-blooded animal such as man.

Abstract: A spreadsheet environment is utilized to interact with a multidimensional data store associated with the enterprise planning session. In general, a conventional spreadsheet application is extended to provide additional functionality for interacting with the multidimensional data store maintained by the enterprise planning system. Instances of the extended spreadsheet application execute on a client computing device, and present a user with a two-dimensional representation of a portion of the multidimensional data store. For example, the extended spreadsheet application may present user with a workbook that includes one or more worksheets within which the user may view and update his planning data. In this manner, the extended spreadsheet application functions as an interface between two-dimensional worksheets maintained by the computing devices and the multidimensional data store maintained by the enterprise planning system.

Abstract: Compounds of formula (I) in which: R1 represents a hydrogen atom or an O-protecting group; R2 represents a hydroxyl, lower alkoxy, carboxaldehyde, lower alk-1-enyl or hydroxy- or lower alkoxy-substituted lower alkyl group; R3 represents a methyl group having ?- or ?-configuration; X represents a C1-3 alkylene group or a valence bond; Y represents a carboxaldehyde group or a group of formula —C(R4)(R5)OR1 where R1 is as defined above and R4 and R5, which may be the same or different, are each selected from hydrogen atoms, alkyl, alkenyl and alkynyl groups such that the total carbon content of R4 and R5 does not exceed three atoms, with the proviso that X is a valence bond when both R4 and R5 are other than hydrogen; and the dotted line signifies that a double bond may optionally be present at the 16(17)-position exhibit potent cell modulating activity, including antiproliferative and antiangiogenic effects.

Abstract: Apparatus for retaining a mail piece includes first and second elements, said elements having an open state in which the first element is spaced from said second element for insertion of a mail item therebetween into a required position and a closed state in which at least one of the first and second elements is displaced toward the other of the first and second elements to clamp the mail piece and further including mail piece retention means mounted on the first element and effective during displacement of the element to retain the mail piece in the required position to which it has been inserted.

Abstract: An enterprise business planning system includes a server to an application server to execute an enterprise planning activity in accordance with a model that defines a set of enterprise users. The system further includes an extension manager to selectively deploy software extensions to the enterprise users in accordance with the model. The model may, for example, define roles for the enterprise users, and the extension manager selectively deploys the software extensions to the enterprise users based on the roles assigned to the enterprise users. As another example, enterprise model may comprises a multi-level hierarchy of related nodes, and associates the enterprise users with the nodes. The extension manager may selectively deploy the software extensions to the enterprise users based on the levels of respective nodes associated with the enterprise users.

Abstract: Compounds of formula (I) in which: R1 represents a hydrogen atom or an O-protecting group; R2 represents a hydroxyl, lower alkoxy, carboxaldehyde, lower alk-1-enyl or hydroxy- or lower alkoxy-substituted lower alkyl group; R3 represents a methyl group having &agr;- or &bgr;-configuration; X represents a C1-3 alkylene group or a valence bond; Y represents a carboxaldehyde group or a group of formula —C(R4)(R5)OR1 where R1 is as defined above and R4 and R5, which may be the same or different, are each selected from hydrogen atoms, alkyl, alkenyl and alkynyl groups such that the total carbon content of R4 and R5 does not exceed three atoms, with the proviso that X is a valence bond when both R4 and R5 are other than hydrogen; and the dotted line signifies that a double bond may optionally be present at the 16(17)-position exhibit potent cell modulating activity, including antiproliferative and antiangiogenic effects.

Abstract: A print head transport mechanism of a postage meter for printing postal indicia which are of greater height than a printing height of a print head comprises a carriage to traverse the print head over a band of a print receiving area. The print head is mounted in a sub-carriage mounted on the carriage and the sub-carriage is displaceable in the direction of printing height of the print head. A cam connected between the sub-carriage and the carriage is operable to displace the sub-carriage. The cam is provided with friction surfaces that engage with friction pads during traverse of the carriage to operate the cam and thereby displace the sub-carriage so that printing is effected in a first band during traverse of the print head in one direction and printing is effected in an adjacent band during traverse of the print head in a second direction opposite to said first direction.

Abstract: An ink jet print head includes an ink jet print module contained in a cartridge housing. The ink jet print module includes a surface containing a plurality of ink jet nozzles and this surface extends in a aperture of the cartridge housing. An element extends from the housing and supports a set of electrical terminals and electrical connection means provide electrical interconnections between electrical contacts of the set of electrical contacts of the ink jet print module and electrical terminals of the set of electrical terminals supported in the element.

Abstract: Apparatus for retaining a mail piece includes first and second elements, said elements having an open state in which the first element is spaced from said second element for insertion of a mail item therebetween into a required position and a closed state in which at least one of the first and second elements is displaced toward the other of the first and second elements to clamp the mail piece and further including mail piece retention means mounted on the first element and effective during displacement of the element to retain the mail piece in the required position to which it has been inserted.