Abstract: The present application relates to particular anti-PAD4 (peptidyl arginine deiminase 4) antibodies, nucleic acids encoding the antibodies, vectors and host cells comprising the nucleic acids, and methods of making and using the antibodies.

Abstract: The present application relates to particular anti-PAD4 (peptidyl arginine deiminase 4) antibodies, nucleic acids encoding the antibodies, vectors and host cells comprising the nucleic acids, and methods of making and using the antibodies.

Abstract: A mixed beverage product includes a container defining an interior chamber, an agitator mechanism coupled to the container, and a beverage contained in the inner chamber in the container. The beverage may be a coffee beverage, or the beverage may be carbonated water and a base beverage, such as fruit juice, veggie juice, or coffee. The agitator is configured to aerate the coffee beverage to form a foam layer on the coffee beverage, or to mix the carbonated water with the base beverage to form a foam layer on the beverage.

Abstract: A mixed beverage product includes a container defining an interior chamber, an agitator mechanism coupled to the container, and a beverage contained in the inner chamber in the container. The beverage may be a coffee beverage, or the beverage may be carbonated water and a base beverage, such as fruit juice, veggie juice, or coffee. The agitator is configured to aerate the coffee beverage to form a foam layer on the coffee beverage, or to mix the carbonated water with the base beverage to form a foam layer on the beverage.

Abstract: A mixed beverage product includes a container defining an interior chamber, an agitator mechanism coupled to the container, and a beverage contained in the inner chamber in the container. The beverage may be a coffee beverage, or the beverage may be carbonated water and a base beverage, such as fruit juice, veggie juice, or coffee. The agitator is configured to aerate the coffee beverage to form a foam layer on the coffee beverage, or to mix the carbonated water with the base beverage to form a foam layer on the beverage.

Abstract: This invention concerns new configurations for biological switches and provides new methods and materials useful for regulating biological events in animal cells. The invention involves recombinant DNA constructs comprising DNA sequences derived from sequences encoding the proteins FRAP, Tor1, Tor2 and other proteins capable of binding to FKBP:rapamycin, other recombinant DNA constructs comprising DNA sequences encoding part or all of an FKBP protein, the proteins encoded by those constructs, cells (especially animal cells) transformed with one or more of the constructs, small molecules (multivalent multimerizing agents) which bind to and are capable of inducing multimerization of the chimeric proteins, and methods for preparing and using the foregoing, including methods involving the intramuscular delivery of such recombinant DNA constructs in AAV virus particles.

Abstract: This invention concerns new configurations for biological switches and provides new methods and materials useful for regulating biological events in animal cells. The invention involves recombinant DNA constructs comprising DNA sequences derived from sequences encoding the proteins FRAP, Tor1, Tor2 and other proteins capable of binding to FKBP:rapamycin, other recombinant DNA constructs comprising DNA sequences encoding part or all of an FKBP protein, the proteins encoded by those constructs, cells (especially animal cells) transformed with one or more of the constructs, small molecules (multivalent multimerizing agents) which bind to and are capable of inducing multimerization of the chimeric proteins, and methods for preparing and using the foregoing, including methods involving the intramuscular delivery of such recombinant DNA constructs in AAV virus particles.

Abstract: Cup handles made from clay have their seams removed by the handle being pushed along a passage of appropriate cross-section in a sponge. The sponge is washed after use by the introduction of water into the passage and by squeezing the sponge. The invention provides for the outer surface of the sponge to be treated all over to render it at least substantially impermeable to water. In use, when the sponge is squeezed, water is expelled only from the passage, and thus the uncontrolled flow of water encountered with sponges having permeable outer surfaces is avoided. Rigid plates may cover those parallel faces of the sponge into which the ends of the passage open, the plates having slots aligned with the ends of the passage. The sponges may be incorporated in a handle de-seaming machine operating cyclically.