Abstract: A special effect system may include a steam generator, a reheater, and a steam separator configured to generate dry steam. The steam generator is coupled to a show element comprising a one or more compartments. Steam from the steam generator passes through the reheater and the steam separator before entering the one or more compartments such that condensate is removed and cooling of the steam within the system between the steam generator and the show element is remedied.

Abstract: One aspect of the present disclosure discloses a probe, including a probe body having a center axis defining a proximal end and a distal end and including an aperture in the distal end; a window affixed in the aperture, wherein the window is substantially optically transparent; and a flange adjoining the proximal end of the probe body, the flange including a sealing surface and a sealing edge, wherein the flange separates an in-process portion of the probe from an ex-process portion of the probe, the in-process portion including at least the probe body, the sealing surface and the sealing edge, where at least the in-process portion of the probe consists essentially of an austenitic stainless steel material. Further aspects include a computer product configured to execute a method employing the probe.

Abstract: Techniques for serving a manifest file of an adaptive streaming video include receiving a request for the manifest file from a user device. The video is encoded at different reference bitrates and each encoded reference bitrate is divided into segments to generate video segment files. The manifest file includes an ordered list of universal resource locators (URLs) that reference a set of video segment files encoded at a particular reference bitrate. A source manifest file that indicates the set of video segment files is identified based on the request. An issued manifest file that includes a first URL and a second URL is generated based on the source manifest file. The first URL references a first domain and the second URL references a second domain that is different from the first domain. The issued manifest file is transmitted to the user device as a response to the request.

Abstract: Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.

Abstract: A kickstand assembly comprises a backplate including a backplate deploy magnet having a first magnetic pole orientation. An upper kickstand plate is slidably connected to the backplate, and a lower kickstand plate is rotatably coupled to the upper kickstand plate. The lower kickstand plate includes a closing magnet having a second magnetic pole orientation that attracts the backplate deploy magnet, and an opening magnet laterally spaced from the closing magnet and having the first magnetic pole orientation that repels the backplate deploy magnet to cause the lower kickstand plate to rotate about the upper kickstand plate when the upper kickstand plate is laterally translated relative to the backplate.

Abstract: Examples of kickstand assemblies for foldable computing devices are provided. In one example, in a foldable computing device comprising a first frame rotatably coupled to a second frame, a method of using a kickstand assembly to release the first frame and the second frame from a closed orientation comprises sliding an upper kickstand plate of the kickstand assembly in a lateral direction relative to the first frame. The method includes, at least on condition of sliding the upper kickstand plate in the lateral direction, biasing the first frame and the second frame to rotate open from the closed orientation.

Abstract: Techniques for serving a manifest file of an adaptive streaming video include receiving a request for the manifest file from a user device. The video is encoded at different reference bitrates and each encoded reference bitrate is divided into segments to generate video segment files. The manifest file includes an ordered list of universal resource locators (URLs) that reference a set of video segment files encoded at a particular reference bitrate. A source manifest file that indicates the set of video segment files is identified based on the request. An issued manifest file that includes a first URL and a second URL is generated based on the source manifest file. The first URL references a first domain and the second URL references a second domain that is different from the first domain. The issued manifest file is transmitted to the user device as a response to the request.

Abstract: Antibodies and compositions of matter useful for the detection, diagnosis and treatment of Epstein Barr Virus (EBV) infection in mammals, and methods of using those compositions of matter for the detection, diagnosis and treatment of EBV infection are described. Also described are proteins, referred to as anti-gp350 antibody probes, and anti-gp350 B-cell probes, that maintain the epitope structure of the CR2-binding region of gp350, but do not bind CR2.

Abstract: Disclosed are methods and devices related to a radial mounting interface holding a compact monolithic telescope, or generally an optical component, with robust optical alignment. An example optical mounting apparatus includes a mounting structure including a plurality of segments that are configured to surround a circumferential area of a monolithic optical device and to hold the monolithic optical device in place, wherein each of the plurality of segments includes a ridged or a grooved interface surface to couple the mounting structure to corresponding grooves or ridges in a surface of the monolithic optical device. The apparatus further includes an elastomeric material confined between the ridged or grooved interface surface of the mounting structure and the one or more corresponding grooves or ridges in the surface of the monolithic optical device. Also disclosed are thermal management features that passively enable diffraction-limited performance of large aperture monolithic optics.

Abstract: Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.

Abstract: Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease.

Abstract: Coronavirus S ectodomain trimers stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the coronavirus S ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to coronavirus in a subject. In additional embodiments, the therapeutically effective amount of the coronavirus S ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing coronavirus infection.

Abstract: One aspect of the present disclosure discloses a probe, including a probe body having a center axis defining a proximal end and a distal end and including an aperture in the distal end; a window affixed in the aperture, wherein the window is substantially optically transparent; and a flange adjoining the proximal end of the probe body, the flange including a sealing surface and a sealing edge, wherein the flange separates an in-process portion of the probe from an ex-process portion of the probe, the in-process portion including at least the probe body, the sealing surface and the sealing edge, where at least the in-process portion of the probe consists essentially of an austenitic stainless steel material. Further aspects include a computer product configured to execute a method employing the probe.

Abstract: Disclosed are recombinant insect ferritin nanoparticles that can be used to display two different trimeric antigens at an equal ratio. Also disclosed are nucleic acids encoding the recombinant insect ferritin nanoparticles and methods of producing the recombinant insect ferritin nanoparticles. Methods for eliciting an immune response in a subject are also provided.

Abstract: The description relates to hinged devices, such as hinged computing devices. One example can include first and second portions that rotate around a hinge shaft that is fixedly secured to the first portion and rotationally secured to the second portion. The second portion defining a first contact surface spaced apart from a second contact surface. Multiple friction clips friction fit around the hinge shaft and rotating with the hinge shaft between the first contact surface and the second contact surface.

Abstract: Techniques for serving a manifest file of an adaptive streaming video include receiving a request for the manifest file from a user device. The video is encoded at different reference bitrates and each encoded reference bitrate is divided into segments to generate video segment files. The manifest file includes an ordered list of universal resource locators (URLs) that reference a set of video segment files encoded at a particular reference bitrate. A source manifest file that indicates the set of video segment files is identified based on the request. An issued manifest file that includes a first URL and a second URL is generated based on the source manifest file. The first URL references a first domain and the second URL references a second domain that is different from the first domain. The issued manifest file is transmitted to the user device as a response to the request.

Abstract: Antibodies and compositions of matter useful for the detection, diagnosis and treatment of Epstein Barr Virus (EBV) infection in mammals, and methods of using those compositions of matter for the detection, diagnosis and treatment of EBV infection are described. Also described are proteins, referred to as anti-gp350 antibody probes, and anti-gp350 B-cell probes, that maintain the epitope structure of the CR2-binding region of gp350, but do not bind CR2.

Abstract: Examples are disclosed relating to friction hinges. In one example, a friction hinge comprises a first stub and adjacent second stub extending from a stub substrate. A first finger extends from a finger substrate between the first stub and the second stub and comprises a distal contacting face that is biased into contact with a first biasing face of the first stub. A second finger adjacent to the first finger extends from the finger substrate between the first stub and the second stub and comprises a distal contacting face that is biased into contact with a second biasing face of the second stub. A pin extends through apertures in the first stub, first finger, second finger, and second stub.

Abstract: Disclosed is a device for determining a concentration of cells of a given size in a sample of fluid, the sample comprising a plurality of cells, comprising: a light source arranged to emit light along a central axis to illuminate the plurality of cells in the fluid sample; a detector arranged to receive light at a plurality of displacements from the central axis, the light having passed through the plurality of cells in the fluid sample, and to produce a plurality of signals, each associated with, and indicative of an intensity of the received light at, a respective one of the plurality of displacements; and a processor arranged to determine a concentration of cells of a given size, based on the plurality of signals from the detector, wherein the processor is arranged to compare the plurality of signals from the detector with one or more pre-stored thresholds or profiles, indicative of a particular concentration.

Abstract: A monitoring system can implement a method including receiving data characterizing first measurements recorded by a sensor in a heating area, second measurements recorded by the sensor in an ambient area, and third measurements recorded by the sensor in a central area, located between the heating area and the ambient area. The method further includes determining a first average temperature, a second average temperature, and a third average temperature. The method further includes computing a first temperature difference between the first average temperature in the heating area and the third average temperature in the central area, and a second temperature difference between second average temperature in the ambient area and the third average temperature of the central area. The method further includes providing the first temperature difference and the second temperature difference.