Abstract: An integrated apparatus includes a toothbrush having a first end and a second end. Between the first and the second end of the toothbrush includes a head, a middle body and a lower body; the head being towards the first end, the lower body towards the second end. The middle body placed between the head and the lower body providing grip area for the apparatus. A plurality of bristles placed above the head of the toothbrush towards the first end. The lower body further includes a contour section, and a floss receptacle section. A floss assembly includes of a floss body and a floss, the floss assembly configured to attach to the floss receptacle section of the toothbrush. The contour section has an upper edge and a lower edge.

Abstract: The present invention is directed to quinoline derivatives, pharmaceutical compositions containing said derivatives and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. For example, the compounds of the present invention are useful in the treatment of metabolic disorders.

Abstract: The present invention is directed to tricyclic indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by endothelial lipase, for example, cardiovascular disorders.

Abstract: The present invention is directed to quinoline derivatives, pharmaceutical compositions containing said derivatives and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. For example, the compounds of the present invention are useful in the treatment of metabolic disorders.

Abstract: The present invention is directed to quinoline derivatives, pharmaceutical compositions containing said derivatives and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. For example, the compounds of the present invention are useful in the treatment of metabolic disorders.

Abstract: The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.

Abstract: A location-controlled communication system for individualized communication between each of a plurality of customer PDA associated with a specific location at an event venue and selected Internet websites. Each physical location in the venue includes at least one location-identifier device. The customer PDA receives location information from the location-identifier device. Information on the PDA including its location is communicated to an EIS server. The EIS server can send particularized data to the PDA that may be based on the location, event, venue or other data and may send other data from the Internet.

Abstract: An ergonomic chin support is designed for use in combination with medical headgear. The headgear has flexible straps adapted for locating a ventilation interface on a patient. The ergonomic chin support comprises a generally arcuate and substantially rigid chin cradle. First and second substantially rigid extensions are formed at opposite ends of the chin cradle, and are adapted for being pulled by respective straps of the headgear to urge the chin cradle against the mandible of the patient. Retaining posts are provided for retaining the ergonomic chin support at a fixed location along respective lengths of the straps.

Abstract: The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.

Abstract: A cap clip for fastening caps together is realized employing pressure type pincer snaps, allowing complex geometrical shapes to be formed while reducing the use of fasteners. In one embodiment, the cap clip includes a generally triangular base and three pincer snaps formed integrally with the base along the outer perimeter. Preferably, each pincer snap is comprised of a pair of convex walls and a shared clasping section lying along a radius of curvature path that are co-centric.

Abstract: The present invention is directed to a compound of Formula (I): or an enantiomer, diastereomer, polymorph or pharmaceutically acceptable salt thereof and methods for preparing said compounds and compositions, intermediates and derivatives thereof, and methods for treating inflammatory or serine protease mediated disorders.

Abstract: A cap clip for fastening caps together is realized employing pressure type pincer snaps, allowing complex geometrical shapes to be formed while reducing the use of fasteners. In one embodiment, the cap clip includes a generally triangular base and three pincer snaps formed integrally with the base along the outer perimeter. Preferably, each pincer snap is comprised of a pair of convex walls and a shared clasping section lying along a radius of curvature path that are co-centric. In another embodiment, each pincer snap includes a single convex plate and concave walls of a twin clasping section consisting of two triangular sections with a spacing centrally disposed therebetween. Each triangular section has two outer concave walls extending vertically upward away from the base, and joined laterally to each other along a corresponding rounded edge.

Abstract: A cap clip for fastening caps together is realized employing pressure type pincer snaps, allowing complex geometrical shapes to be formed while reducing the use of fasteners. In one embodiment, the cap clip includes a generally triangular base and three pincer snaps formed integrally with the base along the outer perimeter. Preferably, each pincer snap is comprised of a pair of convex walls and a shared clasping section lying along a radius of curvature path that are co-centric.

Abstract: The present invention is directed to a compound of Formula (I): or an enantiomer, diastereomer, polymorph or pharmaceutically acceptable salt thereof and methods for preparing said compounds and compositions, intermediates and derivatives thereof, and methods for treating inflammatory or serine protease mediated disorders.

Abstract: The present invention is directed to a compound of formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof, and methods for treating inflammatory and serine protease mediated disorders.

Abstract: The use of a large ambulatory manual breathing unit in combination with a metered dose medication inhaler for delivering medication to a patient, who is either breathing spontaneously or non-spontaneously. The large bag or reservoir of the breathing unit is used to insure minimization of size and homogeneous disbursement of the particles of medication. For non-spontaneous patient breathing, the reservoir's contents are disbursed into the patient by manually or mechanically squeezing the bag, after which the bag returns to its original shape and volume. At one or the other end of the bag, a typical metered dose inhalator is mounted in a manner to disburse the medication into the bag, and directly in line therewith, through an adaptor. The metered dose inhaler collar, into which the inhaler fits, when the inhaler is not in use, is capped.

Abstract: A partition and paneling system comprises connecting means for joining of abutting wall panels together to form an integral wall. The connecting means includes a head section supporting the ceiling and connected to the conventional overhead steel work or black iron. Downwardly extending top guide channels are mounted to the head section and the upper portion of a fastening member is located within the top guide channels and extends downwardly therefrom. The fastening member comprises an enlarged upper portion, an elongated intermediate portion having tapered wedged-shaped blocks at intermediate portions therealong and a lower enlarged portion having a threaded axial aperture which is engaged by a threaded rod. The rod is locked in the lower enlarged portion at one end and has an outwardly extending block at the lower end thereof and an elongated lock nut mounted thereto.