Abstract: Methods and reference compositions for quantifying protein using tagged standards. In an exemplary method, a reference composition and a protein may be electrophoresed in respective lanes of a gel. The reference composition may include quantitation standards of different size and each including a tag present at a different concentration. The quantitation standards and the protein may be transferred from the gel to a solid support to create a blot. Luminescence may be detected from the blot to obtain respective luminescence values separately representing an abundance of the tag of each quantitation standard and an abundance of the protein. A quantity of the protein may be determined using the respective luminescence values.

Abstract: A bioprocessing system includes a first fluid assembly having a first fluid assembly line connected to a first port of a first bioreactor vessel though a first bioreactor line of a first bioreactor vessel, a second fluid assembly having a second fluid assembly line connected to a second port of the first bioreactor vessel through a second bioreactor line of the first bioreactor vessel, and an interconnect line providing for fluid communication between the first fluid assembly and the second fluid assembly, and for fluid communication between the second bioreactor line of the first bioreactor vessel and the first bioreactor line of the first bioreactor vessel.

Abstract: Pathways between reference locations in a physical system are generated based on a layout table. Nodes and edges of the directed graph are associated with cell locations of the layout table. The cell locations define features of the reference locations. Parameters of the nodes and edges are defined based on descriptors recalled from the cells associated with the nodes and edges. The nodes and edges are configured based on the descriptors. Path data regarding potential pathways is generated based on the defined nodes and edges.

Abstract: A sock for improving comfort for a user is provided. The sock includes a foot area having a closed end, an open end opposite the closed end, and a notch extending from an edge of the open end of the sock toward the closed end. When a part of a user's body is inserted into the sock, the notch is configured to expand from a first state, in which edges of the notch are at a first angle with respect to each other, to a second state, in which the edges of the notch are at a second angle with respect to each other, wherein the second angle is greater than the first angle.

Abstract: Various embodiments of a hearing device and a method of using such device are disclosed. The hearing device includes a housing having an inner surface and an outer surface, electronic components disposed within the housing, and a port disposed in the housing and extending between a first end at the outer surface of the housing and a second end disposed within the housing, where the port is acoustically connected to at least one of a speaker or a microphone of the electronic components. The hearing components also include a controller that is electrically connected to a sensor and that is adapted to detect a change in capacitance of the sensor, where the change in capacitance is associated with debris at least partially occluding the port.

Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K? signaling with the compounds and compositions of the disclosure.

Abstract: In certain embodiments, a method for analyzing a retinal image of an eye for retinal disease includes conforming a contact portion of a patient interface to the surface of the eye. A camera stem is received by a sleeve of the patient interface. Light from the camera stem is directed by the sleeve towards the interior of the eye, and light reflected from the interior of the eye is directed by the sleeve towards the camera. Image data generated by the camera is output to a computer. Options representing actions that facilitate analysis of the retinal image are displayed at the computer. The retinal image is displayed at the computer according to the image data. A selection of an option is received by the computer. The action represented by the option is performed by the computer to facilitate analysis of the retinal image.

Abstract: A birdfeeder apparatus for preventing large birds from accessing birdseed includes a housing which is configured for holding and dispensing birdseed. The housing includes a bird support configured to support desired birds. A plurality of guards is coupled to and extend outwardly away from the housing. A spacing between adjacent pairs of the plurality of guards has a size configured to obstruct undesired birds larger than the desired birds from landing on the bird support.

Abstract: A birdfeeder apparatus for preventing large birds from accessing birdseed includes a housing which is configured for holding and dispensing birdseed. The housing includes a bird support configured to support desired birds. A plurality of guards is coupled to and extend outwardly away from the housing. A spacing between adjacent pairs of the plurality of guards has a size configured to obstruct undesired birds larger than the desired birds from landing on the bird support.

Abstract: A coating analyzer is configured to receive electronic image data of a physical coating and to generate information regarding the pigments of the physical coating. The coating analyzer applies a computer vision model trained on baseline image data to the electronic image data. The coating analyzer assigns color values to the pigments forming the electronic image data and generates pigment groups based on the assigned color values. The pigment groups provide color palette data regarding the pigments forming the coating.

Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.

Abstract: Pathways between reference locations in a physical system are generated based on a layout table. Nodes and edges of the directed graph are associated with cell locations of the layout table. The cell locations define features of the reference locations. Parameters of the nodes and edges are defined based on descriptors recalled from the cells associated with the nodes and edges. The nodes and edges are configured based on the descriptors. Path data regarding potential pathways is generated based on the defined nodes and edges.

Abstract: A coating analyzer is configured to receive electronic image data of a physical coating and to generate information regarding the pigments of the physical coating. The coating analyzer applies a computer vision model trained on baseline image data to the electronic image data. The coating analyzer assigns color values to the pigments forming the electronic image data and generates pigment groups based on the assigned color values. The pigment groups provide color palette data regarding the pigments forming the coating.

Abstract: A product count of a number of physical products within a physical grouping of a plurality of the physical products is determined based on an image of the physical grouping. A cycle counter generates image coordinates for visible product surfaces within the image. The cycle counter generates three-dimensional virtual base coordinates for the expected locations of the plurality of the physical products within the physical grouping. The cycle counter determines the actual locations of the visible product surfaces within three-dimensional space based on a comparison of the image coordinates and the virtual base coordinates. The cycle counter determines the product count of the number of physical products within the physical grouping based on the actual locations.

Abstract: Systems and methods for contact imaging of stands with illumination are disclosed herein. A contact imaging system can include a contact imager. The contact imager can include a housing having a base and a lid. The lid can have a closed position against the base and an open position. The contact imager can include a contact area image sensor. The lid can shield the contact area image sensor from ambient light when the lid is in the closed position. The contact imager can include an illuminator that can illuminate at least a portion of a blot on the contact area image sensor when the lid is in the closed position.

Abstract: Pathways between reference locations in a physical system are generated based on a layout table. Nodes and edges of the directed graph are associated with cell locations of the layout table. The cell locations define features of the reference locations. Parameters of the nodes and edges are defined based on descriptors recalled from the cells associated with the nodes and edges. The nodes and edges are configured based on the descriptors. Path data regarding potential pathways is generated based on the defined nodes and edges.

Abstract: Apparatus and associated methods relate to assessing a confidence level of a verbal communication of a person as determined by a machine learning model operating on a video stream of the person. Video data, audio data, and semantic text data are extracted from a video stream of the person. The video data are analyzed to identify a first feature set. The audio data are analyzed to identify a second feature set. The semantic text data are analyzed to identify a third feature set. Using a computer-implemented machine-learning model, a confidence level of the verbal communication of the person is assessed. The confidence level is then associated with a time of the video stream to which the confidence level pertains. The confidence level and the associated time of the video stream are then reported.

Abstract: Apparatus and associated methods relate to invoking an alert based upon a behavior of a patient as determined by a machine learning model operating on an audio stream of the patient. Audio data, and semantic text data are extracted from an audio stream of the patient. The audio data are analyzed to identify a first feature set. The semantic text data are analyzed to identify a second feature set. Using a computer-implemented machine-learning model, a patient behavior of the patient is determined based on the first and/or second features sets. The patient behavior is compared with a set of alerting behaviors corresponding to a patient classification of the patient. The alert is automatically invoked when the patient behavior is determined to be included in the set of alerting behaviors corresponding to the patient classification of the patient.

Abstract: Apparatus and associated methods relate to invoking an alert based upon a behavior of a patient as determined by a machine-learning model operating on a video stream of the patient. Video data, audio data, and semantic text data are extracted from a video stream of the patient. The video data are analyzed to identify first, second, and third features sets of video, audio, and semantic text features, respectively, which have been identified by a computer-implemented machine-learning engine as being indicative of at least one of a set of alerting behaviors corresponding to a patient classification of the patient. Using a computer-implemented machine-learning model, a patient behavior of the patient is determined based on the first, second, and/or third features sets. The patient's behavior is compared with the set of alerting behaviors, and, when the patient's behavior is determined to be included therein, the alert is automatically invoked.

Abstract: A new and distinct cultivar of Loropetalum chinense var. rubrum plant named ‘LRD-51-22’, characterized by its compact, low-growing habit; lustrous dark black-purple foliage color that persists through summer and winter; dark pink flowers in spring; and improved cold hardiness compared to other compact purple-leaf cultivars. The new variety is a Loropetalum, typically for ornamental garden use.