Patents by Inventor Michael Groaning

Michael Groaning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for preparing tubulysins
    Patent number: 9499849
    Abstract: Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: November 22, 2016
    Assignee: Endocyte, Inc.
    Inventors: Iontcho Radoslavov Vlahov, Michael Groaning, Paul Joseph Kleindl, Hari Krishna R. Santhapuram, Fei You, Kevin Yu Wang, Le-Cun Xu, Katheryn Marie Stanford, Allen Ritter, Christopher Paul Leamon
  • PROCESSES FOR PREPARING TUBULYSINS
    Publication number: 20160177363
    Abstract: Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
    Type: Application
    Filed: February 26, 2016
    Publication date: June 23, 2016
    Inventors: Iontcho Radoslavov VLAHOV, Michael GROANING, Paul Joseph KLEINDL, Hari Krishna R. SANTHAPURAM, Fei YOU, Kevin Yu WANG, Le-Cun XU, Katheryn Marie STANFORD, Allen RITTER, Christopher Paul LEAMON
  • Processes for preparing tubulysins
    Patent number: 9273091
    Abstract: Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: March 1, 2016
    Assignee: Endocyte, Inc.
    Inventors: Iontcho Radoslavov Vlahov, Michael Groaning, Paul Joseph Kleindl, Hari Krishna R. Santhapuram, Fei You, Kevin Yu Wang, Le-Cun Xu, Katheryn Marie Stanford, Allen Ritter, Christopher Paul Leamon
  • PROCESSES FOR PREPARING TUBULYSINS
    Publication number: 20150225447
    Abstract: Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
    Type: Application
    Filed: October 20, 2014
    Publication date: August 13, 2015
    Applicant: ENDOCYTE, INC.
    Inventors: Iontcho Radoslavov VLAHOV, Michael GROANING, Paul Joseph KLEINDL, Hari Krishna R. SANTHAPURAM, Fei YOU, Kevin Yu WANG, Le-Cun XU, Katheryn Marie STANFORD, Allen RITTER, Christopher Paul LEAMON
  • Processes for preparing tubulysins
    Patent number: 8889880
    Abstract: Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: November 18, 2014
    Assignee: Endocyte, Inc.
    Inventors: Iontcho Radoslavov Vlahov, Michael Groaning, Paul Joseph Kleindl, Hari Krishna R. Santhapuram, Fei You, Kevin Yu Wang, Le-Cun Xu, Katheryn Marie Stanford, Allen Ritter, Christopher Paul Leamon
  • PROCESSES FOR PREPARING TUBULYSINS
    Publication number: 20130137139
    Abstract: Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
    Type: Application
    Filed: August 5, 2011
    Publication date: May 30, 2013
    Applicant: ENDOCYTE, INC.
    Inventors: Iontcho Radoslavov Vlahov, Michael Groaning, Paul Joseph Kleindl, Hari Krishna R. Santhapuram, Fei You, Kevin Yu Wang, Le-Cun Xu, Katheryn Marie Stanford, Allen Ritter, Paul Christopher Leamon
  • Derivatives of unsaturated, cyclic organic acids
    Publication number: 20070197807
    Abstract: The present invention relates to technology for preparing derivatives of unsaturated, cyclic, organic acids and salts, thereof. Shikimic acid is an example of such an acid. More particularly, the present invention relates to preparing derivatives of these acids or salts thereof that are esterified, ketalized, functionalized with a leaving group, and/or provided with epoxide functionality. Preferred aspects may be used in the synthesis of Oseltamivir Phosphate starting from shikimic acid.
    Type: Application
    Filed: December 22, 2006
    Publication date: August 23, 2007
    Inventors: Richard Gabel, Michael Groaning, David Johnston