Patents by Inventor Michael Grote

Michael Grote has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Covalently linked antigen-antibody conjugates
    Patent number: 12023378
    Abstract: Herein is reported a conjugate comprising an antigen and an antibody that specifically binds to the antigen wherein a covalent bond is formed between the antigen and an amino acid residue in the CDR2 of the antibody, an antibody comprising a cysteine residue at amino acid position 53 (according to Kabat) in the heavy chain CDR2 and uses thereof.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: July 2, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joerg Benz, Ulrich Brinkmann, Stefan Dengl, Sebastian Dziadek, Guy Georges, Michael Grote, Alexander Haas, Eike Hoffmann
  • Method for implementing at least one power supply procedure from at least one power supply unit to at least one transportation vehicle to be supplied with power
    Patent number: 10710459
    Abstract: A method for supplying power from at least one power supply unit to transportation vehicles requiring a power supply, in which a position of a transportation vehicle-side power supply interface of a transportation vehicle requiring power is determined for each transportation vehicle and the transportation vehicle-side power supply interface is automatically coupled to a power supply interface of the power supply unit by the power supply interface of the power supply unit being moved by a robot to the transportation vehicle-side power supply interface and coupled thereto. A robot is responsible for coupling transportation vehicles to a suitable power supply interface of the power supply unit.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: July 14, 2020
    Assignees: VOLKSWAGEN AG, KUKA DEUTSCHLAND
    Inventors: Daniel Schütz, Michael Grote, Jürgen Stieg, Lutz Junge, Sven Horstmann, Thorsten Bagdonat, Sebastian Grysczyk, Andreas Weiser, Norbert Settele
  • COVALENTLY LINKED ANTIGEN-ANTIBODY CONJUGATES
    Publication number: 20200164064
    Abstract: Herein is reported a conjugate comprising an antigen and an antibody that specifically binds to the antigen wherein a covalent bond is formed between the antigen and an amino acid residue in the CDR2 of the antibody, an antibody comprising a cysteine residue at amino acid position 53 (according to Kabat) in the heavy chain CDR2 and uses thereof.
    Type: Application
    Filed: October 29, 2019
    Publication date: May 28, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Joerg BENZ, Ulrich BRINKMANN, Stefan DENGL, Sebastian DZIADEK, Guy GEORGES, Michael GROTE, Alexander HAAS, Eike HOFFMANN
  • Covalently linked antigen-antibody conjugates
    Patent number: 10517945
    Abstract: Herein is reported a conjugate comprising an antigen and an antibody that specifically binds to the antigen wherein a covalent bond is formed between the antigen and an amino acid residue in the CDR2 of the antibody, an antibody comprising a cysteine residue at amino acid position 53 (according to Kabat) in the heavy chain CDR2 and uses thereof.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: December 31, 2019
    Assignee: HOFFMAN-LA ROCHE INC.
    Inventors: Joerg Benz, Ulrich Brinkmann, Stefan Dengl, Sebastian Dziadek, Guy Georges, Michael Grote, Alexander Haas, Eike Hoffmann
  • METHOD FOR IMPLEMENTING AT LEAST ONE POWER SUPPLY PROCEDURE FROM AT LEAST ONE POWER SUPPLY UNIT TO AT LEAST ONE TRANSPORTATION VEHICLE TO BE SUPPLIED WITH POWER
    Publication number: 20190001832
    Abstract: A method for supplying power from at least one power supply unit to transportation vehicles requiring a power supply, in which a position of a transportation vehicle-side power supply interface of a transportation vehicle requiring power is determined for each transportation vehicle and the transportation vehicle-side power supply interface is automatically coupled to a power supply interface of the power supply unit by the power supply interface of the power supply unit being moved by a robot to the transportation vehicle-side power supply interface and coupled thereto. A robot is responsible for coupling transportation vehicles to a suitable power supply interface of the power supply unit.
    Type: Application
    Filed: December 19, 2016
    Publication date: January 3, 2019
    Inventors: Daniel SCHÜTZ, Michael GROTE, Jürgen STIEG, Lutz JUNGE, Sven HORSTMANN, Thorsten BAGDONAT, Sebastian GRYSCZYK, Andreas WEISER, Norbert SETTELE
  • METHOD FOR IMPLEMENTING POWER SUPPLY PROCEDURES FROM AT LEAST ONE POWER SUPPLY UNIT TO A PLURALITY OF TRANSPORTATION VEHICLES TO BE SUPPLIED WITH POWER
    Publication number: 20190001831
    Abstract: A method for supplying power from at least one power supply unit to transportation vehicles requiring a power supply, in which a position of a transportation vehicle-side power supply interface of a transportation vehicle requiring power is determined for each vehicle and the transportation vehicle-side power supply interface is automatically coupled to a power supply interface of the power supply unit by the power supply interface of the power supply unit being moved by a robot to the transportation vehicle-side power supply interface and coupled thereto. A robot is responsible for coupling transportation vehicles to a suitable power supply interface of the power supply unit.
    Type: Application
    Filed: December 19, 2016
    Publication date: January 3, 2019
    Inventors: Daniel SCHÜTZ, Michael GROTE, Jürgen STIEG, Lutz JUNGE, Sven HORSTMANN, Thorsten BAGDONAT, Sebastian GRYSCZYK, Andreas WEISER, Norbert SETTELE
  • Anti-biotin antibodies and methods of use
    Patent number: 9765153
    Abstract: The invention provides anti-biotin antibodies and methods of using the same.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: September 19, 2017
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Ulrich Brinkmann, Guy Georges, Michael Grote, Eike Hoffmann
  • COVALENTLY LINKED ANTIGEN-ANTIBODY CONJUGATES
    Publication number: 20150258209
    Abstract: Herein is reported a conjugate comprising an antigen and an antibody that specifically binds to the antigen wherein a covalent bond is formed between the antigen and an amino acid residue in the CDR2 of the antibody, an antibody comprising a cysteine residue at amino acid position 53 (according to Kabat) in the heavy chain CDR2 and uses thereof.
    Type: Application
    Filed: December 19, 2014
    Publication date: September 17, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: JOERG BENZ, ULRICH BRINKMANN, STEFAN DENGL, SEBASTIAN DZIADEK, GUY GEORGES, MICHAEL GROTE, ALEXANDER HAAS, EIKE HOFFMANN
  • ANTI-BIOTIN ANTIBODIES AND METHODS OF USE
    Publication number: 20150232577
    Abstract: The invention provides anti-biotin antibodies and methods of using the same.
    Type: Application
    Filed: December 19, 2014
    Publication date: August 20, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: ULRICH BRINKMANN, GUY GEORGES, MICHAEL GROTE, EIKE HOFFMANN
  • Bi-specific digoxigenin binding antibodies
    Patent number: 9050375
    Abstract: This invention relates to bispecific antibodies and antibody fragments against a target protein and a hapten, wherein the hapten is PEG or biotin, most preferably digoxigenin, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: June 9, 2015
    Assignee: Hoffmann-La Roche, Inc.
    Inventors: Birgit Bramlage, Ulrich Brinkmann, Rebecca Croasdale, Simone Dill, Wilma Dormeyer, Guy Georges, Michael Grote, Alexander Haas, Eike Hoffmann, Ludger Markus Ickenstein, Kerstin Jahn-Hofmann, Matthias John, Silke Metz, Olaf Mundigl, Werner Scheuer, Jan Olaf Stracke
  • BI-SPECIFIC DIGOXIGENIN BINDING ANTIBODIES
    Publication number: 20120282280
    Abstract: This invention relates to bispecific antibodies and antibody fragments against a target protein and a hapten, wherein the hapten is PEG or biotin, most preferably digoxigenin, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical 5 compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: June 30, 2010
    Publication date: November 8, 2012
    Inventors: Birgit Bramlage, Ulrich Brinkmann, Rebecca Croasdale, Simone Dill, Wilma Dormeyer, Guy Georges, Michael Grote, Alexander Haas, Eike Hoffman, Ludger Markus Ickenstein, Kerstin Jahn-Hofman, Matthias John, Silke Metz, Olaf Mundigl, Werner Scheuer, Jan Olaf Stracke