Abstract: A process and an apparatus for preparing and carrying out NMR measurements on substrate samples (3.1), individual solutions of the substrate samples (3.1) being prepared by means of a pipetting system (1) and being fed to a flow cell (16) for preparation and carrying out of NMR measurements, it being possible to flush the feed apparatus (7) and the pipetting system (1) with at least one solvent (8, 9) are described. A workstation (54) recording the NMR spectrum of the sample and a computer (53) controlling the pipetting system (1) access a common directory tree (32) which contains directories (33.1 to 33.9) with files which define the samples and are called up in such a way as to ensure that the directories (33.1 to 33.9) are worked through in a time-interleaved manner.