Patents by Inventor Michael Höpfner

Michael Höpfner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4,5-diarylimidazole derivatives as HDAC inhibitors
    Patent number: 9868750
    Abstract: The present invention relates to a 4,5-diarylimidazole derivative of formulae (I), (II) or (III): or a pharmaceutically acceptable salt thereof, wherein the 4,5-diarylimidazole derivative has a hydroxamic acid residue at a first aryl ring and a residue R1 at a second aryl ring; and wherein R1 is hydrogen, a halogen atom or an unsubstituted or substituted alkoxy group; R2 is independently selected from an unsubstituted or substituted alkyl, alkoxy or alkene group; M is a metal atom; L is a halogen atom, an unsubstituted or substituted phosphane, sulfane, arene or alkene group or a 4,5-diarylimidazole-derivative of formula (I); and n is an integer of from 1 to 5.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: January 16, 2018
    Assignees: CHARITÉ—UNIVERSITÄTSMEDIZIN BERLIN, UNIVERSITÄT BAYREUTH
    Inventors: Michael Höpfner, Bernhard Biersack, Rainer Schobert, Katharina Mahal
  • 4,5-DIARYLIMIDAZOLE DERIVATIVES AS HDAC INHIBITORS
    Publication number: 20170197992
    Abstract: The present invention relates to a 4,5-diarylimidazole derivative of formulae (I), (II) or (III): or a pharmaceutically acceptable salt thereof, wherein the 4,5-diarylimidazole derivative has a hydroxamic acid residue at a first aryl ring and a residue R1 at a second aryl ring; and wherein R1 is hydrogen, a halogen atom or an unsubstituted or substituted alkoxy group; R2 is independently selected from an unsubstituted or substituted alkyl, alkoxy or alkene group; M is a metal atom; L is a halogen atom, an unsubstituted or substituted phosphane, sulfane, arene or alkene group or a 4,5-diarylimidazole-derivative of formula (I); and n is an integer of from 1 to 5.
    Type: Application
    Filed: July 13, 2015
    Publication date: July 13, 2017
    Inventors: Michael Höpfner, Bernhard Biersack, Rainer Schobert, Katharina Mahal