Patents by Inventor Michael H. Roehrl

Michael H. Roehrl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of zwitterionic polysaccharides for the specific modulation of immune processes
    Patent number: 8008276
    Abstract: The invention relates to three-dimensional molecular structure determination of polymers, three-dimensional computer molecular modeling, rational drug design, and immunomodulatory polymers. In particular the invention is directed to immunomodulatory polymers, as well as to methods for designing, selecting, and screening therapeutic agents having immunomodulatory activity.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: August 30, 2011
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Julia Ying Wang, Michael H. Roehrl, Dennis L. Kasper
  • USE OF ZWITTERIONIC POLYSACCHARIDES FOR THE SPECIFIC MODULATION OF IMMUNE PROCESSES
    Publication number: 20090317410
    Abstract: The invention relates to three-dimensional molecular structure determination of polymers, three-dimensional computer molecular modeling, rational drug design, and immunomodulatory polymers. In particular the invention is directed to immunomodulatory polymers, as well as to methods for designing, selecting, and screening therapeutic agents having immunomodulatory activity.
    Type: Application
    Filed: May 22, 2009
    Publication date: December 24, 2009
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Julia Ying Wang, Michael H. Roehrl, Dennis L. Kasper
  • Use of zwitterionic polysaccharides for the specific modulation of immune processes
    Patent number: 7629330
    Abstract: The invention relates to three-dimensional molecular structure determination of polymers, three-dimensional computer molecular modeling, rational drug design, and immunomodulatory polymers. In particular the invention is directed to immunomodulatory polymers, as well as to methods for designing, selecting, and screening therapeutic agents having immunomodulatory activity.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: December 8, 2009
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Ying Wang, Michael H. Roehrl, Dennis L. Kasper
  • Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases
    Publication number: 20040002117
    Abstract: Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein-protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.
    Type: Application
    Filed: February 4, 2003
    Publication date: January 1, 2004
    Inventors: Patrick G. Hogan, Anjana Rao, Jose Aramburu, Michael H. A. Roehrl, Gerhard Wagner, Sunghyun Kang