Patents by Inventor Michael H. Rosenthal
Michael H. Rosenthal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8548571Abstract: The present invention relates to methods and devices for predicting restenosis, and for treating atherosclerosis to prevent or reduce the incidence of restenosis. Methods of predicting restenosis in a stenosed peripheral artery may include quantitative histology of the vessel. For example, a method of treating a stenosed artery (and particularly a peripheral artery) may include the steps of determining a level of hypercellularity and one or more of the lipid-richness and extent of inflammatory cell inclusion in the tissue. An index of restenosis based on the hypercellularity and lipid richness and/or extent of inflammatory cell inclusion in the tissue may be determined. Systems for treating or preventing restenosis may include one or more imaging modalities for imaging tissue regions and determining the level of hypercellularity and one or more of the degree of lipid-richness and the extent of inflammatory cell inclusion in the tissue region.Type: GrantFiled: December 8, 2010Date of Patent: October 1, 2013Assignee: Avinger, Inc.Inventors: Xuanmin He, John B. Simpson, Michael H. Rosenthal, John F. Black
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Publication number: 20130116782Abstract: Apparatus and methods for nipple and breast formation are described where devices precondition or expand a target nipple tissue to reduce the pressure exerted by the skin on an eventual implant. Generally, the apparatus comprises a mold having a contact surface which is curved in conformance with a breast upon which the mold is positionable, the contact surface having an adhesive for securement upon the breast, and the mold defining a cavity along the contact surface which conforms to a size of a nipple to be formed upon the breast and where the cavity further comprises the adhesive for securement to the nipple. A breast enlargement device comprises a cup larger than the target breast and further defines an inner surface which adheres to the breast when contacted.Type: ApplicationFiled: September 7, 2012Publication date: May 9, 2013Applicant: Tau Tona Group Research and Development Company, L.L.C.Inventors: Kenneth N. HORNE, Sergio SALINAS, Geoffrey C. GURTNER, Michael H. ROSENTHAL, Christopher S. JONES, Joseph RIMSA
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Publication number: 20120330336Abstract: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.Type: ApplicationFiled: June 28, 2012Publication date: December 27, 2012Applicant: TYCO HEALTHCARE GROUP LPInventors: John B. Simpson, Himanshu Patel, Greg Stine, Brett Follmer, Michael H. Rosenthal, Mehrdad Farhangnia
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Publication number: 20120226214Abstract: The methods, procedures, kits, and devices described herein assist with the healing process of tissue that was previously or simultaneously treated for a therapeutic or cosmetic effect. The methods, procedures, kits, and devices described herein can also provide temporary simulated results of a cosmetic procedure to allow for visual assessment to select the type of procedure or for treatment planning in advance of the surgical procedure.Type: ApplicationFiled: March 2, 2012Publication date: September 6, 2012Applicant: Neodyne Biosciences, Inc.Inventors: Geoffrey C. Gurtner, Michael T. Longaker, Reinhold H. Dauskardt, Paul Yock, John A. Zepeda, Kenneth N. Horne, Bankim H. Mehta, Michael H. Rosenthal, Joseph Rimsa, Sergio Salinas, Melanie Harris, Greg Spooner, Kin Chan
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Publication number: 20120209248Abstract: Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented.Type: ApplicationFiled: February 10, 2012Publication date: August 16, 2012Applicant: Tau Tona Group Research and Development Company, L.L.C.Inventors: Geoffrey C. GURTNER, Michael H. ROSENTHAL, Brian J. DOMECUS, Darin GITTINGS, Kinman HONG
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Patent number: 8226674Abstract: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.Type: GrantFiled: April 9, 2010Date of Patent: July 24, 2012Assignee: Tyco Healthcare Group LPInventors: John B. Simpson, Himanshu Patel, Greg Stine, Brett Follmer, Michael H. Rosenthal, Mehrdad Farhangnia
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Publication number: 20120101575Abstract: Apparatus and methods for nipple and breast formation are described where devices precondition or expand a target nipple tissue to reduce the pressure exerted by the skin on an eventual implant. Generally, the apparatus comprises a mold having a contact surface which is curved in conformance with a breast upon which the mold is positionable, the contact surface having an adhesive for securement upon the breast, and the mold defining a cavity along the contact surface which conforms to a size of a nipple to be formed upon the breast and where the cavity further comprises the adhesive for securement to the nipple. A breast enlargement device comprises a cup larger than the target breast and further defines an inner surface which adheres to the breast when contacted.Type: ApplicationFiled: October 20, 2011Publication date: April 26, 2012Applicant: TauTona Group Research and Development Company, L.L.C.Inventors: Kenneth N. HORNE, Michael H. ROSENTHAL, Geoffrey C. GURTNER, Christopher S. Jones, Sergio Salinas, Joseph Rimsa
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Publication number: 20110263936Abstract: The present invention relates to methods and devices for predicting restenosis, and for treating atherosclerosis to prevent or reduce the incidence of restenosis. Methods of predicting restenosis in a stenosed peripheral artery may include quantitative histology of the vessel. For example, a method of treating a stenosed artery (and particularly a peripheral artery) may include the steps of determining a level of hypercellularity and one or more of the lipid-richness and extent of inflammatory cell inclusion in the tissue. An index of restenosis based on the hypercellularity and lipid richness and/or extent of inflammatory cell inclusion in the tissue may be determined. Systems for treating or preventing restenosis may include one or more imaging modalities for imaging tissue regions and determining the level of hypercellularity and one or more of the degree of lipid-richness and the extent of inflammatory cell inclusion in the tissue region.Type: ApplicationFiled: December 8, 2010Publication date: October 27, 2011Inventors: Xuanmin He, John B. Simpson, Michael H. Rosenthal, John F. Black
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Patent number: 8012121Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: GrantFiled: June 26, 2007Date of Patent: September 6, 2011Assignee: AngioDynamics, Inc.Inventors: Harry B. Goodson, IV, Jeffrey M. Elkins, Samir R. Patel, Aurelio Valencia, Ricardo Aboytes, Craig A. Ball, Randy J. Kesten, Andrew K. Kramer, Sam G. Payne, Sophia Pesotchinsky, Michael H. Rosenthal
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Patent number: 7914503Abstract: Two renal delivery members have two distal ports that are adapted to be positioned within two renal arteries via their corresponding renal ostia at unique locations along an abdominal aortic wall. A proximal coupler assembly is outside the body and is coupled to deliver material to the two distal ports for bi-lateral renal therapy. One or both of the delivery members may be self-cannulating into the corresponding renal ostium, or may be controllably steered into the respective ostium. Non-occlusive anchors may be coupled with one or both of the delivery members at anchoring positions in the renal artery or abdominal aorta to secure the renal delivery member within the renal artery. Renal-active fluid agents are coupled to the bi-lateral delivery system. Another renal therapy system cannulates a renal vein from the vena cava and controls a retrograde delivery of agents to the respective kidney.Type: GrantFiled: March 16, 2005Date of Patent: March 29, 2011Assignee: Angio DynamicsInventors: Harry B. Goodson, IV, Jeffrey M. Elkins, Samir R. Patel, Aurelio Valencia, Ricardo Aboytes, Craig A. Ball, Randy J. Kesten, Andrew W. Kramer, Sam G. Payne, Sophia Pesotchinsky, Michael H. Rosenthal
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Publication number: 20110021926Abstract: Catheter-based Optical Coherence Tomography (OCT) systems utilizing an optical fiber that is positioned off-axis of the central longitudinal axis of the catheter have many advantage over catheter-based OCT systems, particularly those having centrally-positioned optical fibers or fibers that rotate independently of the elongate body of the catheter. An OCT system having an off-axis optical fiber for visualizing the inside of a body lumen may be rotated with the body of the elongate catheter, relative to a handle portion. The handle may include a fiber management pathway for the optical fiber that permits the off-axis optical fiber to rotate with the catheter body relative to the handle. The system may also include optical processing elements adapted to prepare and process the OCT image collected by the off-axis catheter systems described herein.Type: ApplicationFiled: July 1, 2010Publication date: January 27, 2011Inventors: Maegan K. SPENCER, Christopher B. White, Charles W. McNall, Dennis W. Jackson, Michael Zung, Nicholas J. Spinelli, Benjamin Ngo, Evangeline Lumabas, Kin F. Chan, John F. Black, Michael H. Rosenthal, John B. Simpson
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Publication number: 20110004107Abstract: Described herein are atherectomy catheters, systems and methods that include a distal tip region that may be moved laterally so that its long axis is parallel with the long axis of the main catheter body axis. Displacing the distal tip region laterally out of the main catheter body axis exposes an annular blade and opens a passageway for cut tissue to enter a storage region within the catheter. The annular blade may be internally coupled to a drive shaft that rotates the blade, and thus the exposed blade edge may have the same crossing profile (OD) as the rest of the distal end region of the catheter. Also described herein are gear-driven atherectomy devices that may use a cable drive shaft to actuate the annular blade. Both push-to-cut and pull-to-cut variations are described, as are methods for cutting tissue and systems including these atherectomy catheters.Type: ApplicationFiled: July 1, 2010Publication date: January 6, 2011Inventors: Michael H. Rosenthal, Michael Zung, Nicholas J. Spinelli, Charles W. McNall, John B. Simpson, John F. Black
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Publication number: 20100305452Abstract: Described herein are catheters for use with Optical Coherence Tomography (OCT) that include an optical fiber core having a first refractive index and an interface medium having a second refractive index, where the first and second refractive indexes are mismatched such that receiving electronics configured to receive optical radiation reflected from the reference interface and the target operate in a total noise range that is within 5 dB of the shot noise limit. These OCT catheters may include a silicon die mirror having a reflective coating that is embedded in the interface medium. The optical fiber can be fixed at just the distal end of the catheter, and may be managed within a handle that is attached to the proximal end of the catheter body, and is configured to allow rotation of the both catheter body and the optical fiber relative to the handle.Type: ApplicationFiled: May 28, 2010Publication date: December 2, 2010Inventors: John F. Black, Maegan K. Spencer, Michael Zung, Charles W. McNall, Evangeline Lumabas, Michael H. Rosenthal, John B. Simpson
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Publication number: 20100256483Abstract: A device for use in a process that involves accessing an epidural space includes an elongated member having a distal end and a proximal end, a sensor located at the distal end of the elongated member, a handle coupled to the proximal end of the elongated member, and an indicator coupled to the sensor, wherein the indicator is configured to provide a sensory indication for assisting a user to identify a desired entry path to access an epidural space, wherein the indicator is configured to provide the sensory indication based at least in part on a signal received from the sensor.Type: ApplicationFiled: April 2, 2010Publication date: October 7, 2010Applicant: InSite Medical Technologies, Inc.Inventors: James Wall, Kenneth Wu, Eric Willis, Zachary J. Malchano, Wenkang Qi, Wilfred Samson, Michael H. Rosenthal
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Patent number: 7780628Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: GrantFiled: May 1, 2000Date of Patent: August 24, 2010Assignee: AngioDynamics, Inc.Inventors: Gad Keren, Ascher Shmulewitz, Benjamin Spenser, Michael Arad, Randy J. Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Publication number: 20100198240Abstract: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.Type: ApplicationFiled: April 9, 2010Publication date: August 5, 2010Applicant: FOX HOLLOW TECHNOLOGIES, INC.Inventors: John B. Simpson, Himanshu Patel, Greg Stine, Brett Follmer, Michael H. Rosenthal, Mehrdad Farhangnia
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Patent number: 7766892Abstract: Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a “once-through” fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.Type: GrantFiled: May 21, 2002Date of Patent: August 3, 2010Inventors: Gad Keren, Ascher Shmulewitz, Benjamin Spenser, Michael Arad, Randy J. Kesten, Sophia Pesotchinsky, Michael H. Rosenthal, Andrew W. Kramer, Sam G. Payne
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Patent number: 7713279Abstract: A method of removing material from a blood flow lumen generally includes providing a device having a cutting element and an opening, advancing the device through the blood flow lumen to a site where material is to be removed, forcing the opening toward a wall of the site where material is to be removed, and moving the cutting element and the opening so that material in the blood flow lumen is cut by the cutting element and directed into the opening for removal as the cutting element and opening are moved through the blood flow lumen. In some embodiments, the device may be deflected or bent to force the opening toward a wall to remove material. The cutting element may be rotatable and may have an axis that is movable, that is not parallel to the longitudinal axis of the device, or both. In some embodiments, the cutting element is movable between retracted and deployed positions for advancing the device to a site for treatment and for removing material, respectively.Type: GrantFiled: April 22, 2003Date of Patent: May 11, 2010Assignee: Fox Hollow Technologies, Inc.Inventors: John B. Simpson, Michael H. Rosenthal, Himanshu Patel, Gautama B. Venegas
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Patent number: 7708749Abstract: A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.Type: GrantFiled: December 14, 2004Date of Patent: May 4, 2010Assignee: Fox Hollow Technologies, Inc.Inventors: John B. Simpson, Himanshu Patel, Greg Stine, Brett Follmer, Michael H. Rosenthal, Mehrdad Farhangnia
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Publication number: 20090299394Abstract: A method of removing material from a blood flow lumen generally includes providing a device having a cutting element and an opening, advancing the device through the blood flow lumen to a site where material is to be removed, forcing the opening toward a wall of the site where material is to be removed, and moving the cutting element and the opening so that material in the blood flow lumen is cut by the cutting element and directed into the opening for removal as the cutting element and opening are moved through the blood flow lumen. In some embodiments, the device may be deflected or bent to force the opening toward a wall to remove material. The cutting element may be rotatable and may have an axis that is movable, that is not parallel to the longitudinal axis of the device, or both.Type: ApplicationFiled: April 28, 2009Publication date: December 3, 2009Applicant: FOX HOLLOW TECHNOLOGIES, INC.Inventors: John B. Simpson, Michael H. Rosenthal, Himanshu Patel, Gautama B. Venegas