Abstract: A composition includes a crosslinked polysiloxane elastomer with 2 or more carbon-oxygen-silicon linkages between a polysaccharide component and polysiloxane component, where the polysaccharide component is other than a cellulose or starch component.

Abstract: In a patient simulator in particular premature infant, newborn or infant simulator, comprising a thorax replication, which comprises a chest replication with at least one liftable and lowerable chest element for simulating a lifting and lowering of the thorax, abdominal wall mechanics, which comprise an abdominal wall replication with at least one liftable and lowerable abdominal wall element for simulating a lifting and lowering of the abdominal wall, a lung simulator, an anatomical trachea replication opening out into a cavity, an anatomical oesophagus replication opening out into a cavity and a control unit, the patient simulator includes at least one sensor whose sensor data is transmitted to the control unit to determine whether the ventilation gas supplied to the patient simulator is conducted into the trachea replication or into the oesophagus replication.

Abstract: In a patient simulator, in particular a premature baby, newborn or child simulator, including a simulated thorax, a pneumatic lung simulator and a simulated trachea leading to the lung simulator, wherein the simulated thorax includes a simulated chest including at least one liftable and lowerable chest element to simulate lifting and lowering of the chest, the at least one liftable and lowerable chest element cooperates with a lifting and lowering mechanism actuatable independently of the lung simulator.

Abstract: The present disclosure relates to a method of synthesizing imidazopyrrolidinone derivative, such as compound of formula (I), or a solvate including hydrate thereof, or a co-crystal thereof, and/or intermediates thereof, their use as pharmaceuticals and the use of intermediates.

Abstract: In a patient simulator in particular premature infant, newborn or infant simulator, comprising a thorax replication, which comprises a chest replication with at least one liftable and lowerable chest element for simulating a lifting and lowering of the thorax, abdominal wall mechanics, which comprise an abdominal wall replication with at least one liftable and lowerable abdominal wall element for simulating a lifting and lowering of the abdominal wall, a lung simulator, an anatomical trachea replication opening out into a cavity, an anatomical oesophagus replication opening out into a cavity and a control unit, the patient simulator includes at least one sensor whose sensor data is transmitted to the control unit to determine whether the ventilation gas supplied to the patient simulator is conducted into the trachea replication or into the oesophagus replication.

Abstract: The present disclosure relates to a method of synthesizing imidazopyrrolidi-none derivative, such as compound of formula (I), or a solvate including hydrate thereof, or a co-crystal thereof, and/or intermediates thereof, their use as pharmaceuticals and the use of intermediates.

Abstract: In a patient simulator, in particular a premature baby, newborn or child simulator, including a simulated thorax, a pneumatic lung simulator and a simulated trachea leading to the lung simulator, wherein the simulated thorax includes a simulated chest including at least one liftable and lowerable chest element to simulate lifting and lowering of the chest, the at least one liftable and lowerable chest element cooperates with a lifting and lowering mechanism actuatable independently of the lung simulator.

Abstract: A collaboration system provides enhanced user interface to enable users to interact with electronic devices. In one embodiment, users can add content to a digital system by using a pen that streams coordinates so that input to the digital system may be based on conventional pen and paper handwriting. In another embodiment, a pie-based menu system is used for input to large display area digital devices in which an occluded portion of the pie-based menu system is not used for direct input by the user. The selection of which areas of the pie-based menu system should be omitted from use is adaptive and responsive to whether the user is left-handed or right-handed, and the wrist angle defined by the user's posture. In still another embodiment, an ergonomic open-shaped pie menu system is provided to facilitate selection of options on a digital surface.

Abstract: A collaboration system provides enhanced user interface to enable users to interact with electronic devices. In one embodiment, users can add content to a digital system by using a pen that streams coordinates so that input to the digital system may be based on conventional pen and paper handwriting. In another embodiment, a pie-based menu system is used for input to large display area digital devices in which an occluded portion of the pie-based menu system is not used for direct input by the user. The selection of which areas of the pie-based menu system should be omitted from use is adaptive and responsive to whether the user is left-handed or right-handed, and the wrist angle defined by the user's posture. In still another embodiment, an ergonomic open-shaped pie menu system is provided to facilitate selection of options on a digital surface.

Abstract: There is provided an sensing device, comprising: a substrate; a sensor ink printed onto the substrate; a conductive polymer ink printed onto the sensor ink; a conductive carbon paste formed on the polymer ink; and a conductive silver ink printed on the conductive carbon paste. There is also provided a sensing device for processing a signal generated by the input device, the sensing device comprising: an operational amplifier to amplify the signal; a filter to filter signal noise from the signal; an adder to apply an offset and attenuation to the signal; a microcontroller comprising an analog to digital converter to convert the signal into a digital output signal.

Abstract: The present invention relates to Factor IX polypeptides conjugated to heparosan (HEP) polymers, methods for the manufacture thereof and uses of such conjugates. The resultant conjugates may be used—for example—in the treatment or prevention of bleeding disorders such as haemophilia B.

Abstract: An apparatus and method for supplying virgin sealer and reclaim sealer to a sealer applicator. A closed loop path including a first fluid flow path is coupled between a source of virgin sealer and the applicator and includes a recirculation path from the applicator back to the source of virgin material. A reclaim sealer supply is coupled to the first fluid flow path. Valves open and close the virgin sealer supply and the reclaim sealer supply to alternately supply virgin sealer or reclaim sealer to the applicator. Whenever the first fluid flow path contains reclaim sealer, a valve blocks flow to the recirculation path to prevent reclaim sealer from being recirculated into the source of virgin sealer.

Abstract: The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.

Abstract: A collaboration system provides enhanced user interface to enable users to interact with electronic devices. In one embodiment, users can add content to a digital system by using a pen that streams coordinates so that input to the digital system may be based on conventional pen and paper handwriting. In another embodiment, a pie-based menu system is used for input to large display area digital devices in which an occluded portion of the pie-based menu system is not used for direct input by the user. The selection of which areas of the pie-based menu system should be omitted from use is adaptive and responsive to whether the user is left-handed or right-handed, and the wrist angle defined by the user's posture. In still another embodiment, an ergonomic open-shaped pie menu system is provided to facilitate selection of options on a digital surface.

Abstract: The present invention relates to FVIII conjugated to heparosan (HEP) polymers, methods for the manufacture thereof and uses of such conjugates. The resultant conjugates may be used in the treatment or prevention of bleeding disorders such as haemophilia.

Abstract: The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.

Abstract: The present invention relates to a multi-touch display system that supports both multi-touch human input as well as input from a digital pen. The display system has a display panel that is configured to allow human touches along a front surface to be detected and tracked. The display panel also includes a location pattern that preferably covers the viewable areas of the display panel. The location pattern is configured to allow any location within the location pattern to be detected by analyzing a portion of the display pattern that is associated with the particular location. The digital pen is used to “write” on the display panel, wherein such a writing function involves detecting the location where writing occurs and controlling display content that is displayed on the display panel to reflect what is being written.

Abstract: A collaboration system provides enhanced user interface to enable users to interact with electronic devices. In one embodiment, users can add content to a digital system by using a pen that streams coordinates so that input to the digital system may be based on conventional pen and paper handwriting. In another embodiment, a pie-based menu system is used for input to large display area digital devices in which an occluded portion of the pie-based menu system is not used for direct input by the user. The selection of which areas of the pie-based menu system should be omitted from use is adaptive and responsive to whether the user is left-handed or right-handed, and the wrist angle defined by the user's posture. In still another embodiment, an ergonomic open-shaped pie menu system is provided to facilitate selection of options on a digital surface.

Abstract: There is provided an sensing device, comprising: a substrate; a sensor ink printed onto the substrate; a conductive polymer ink printed onto the sensor ink; a conductive carbon paste formed on the polymer ink; and a conductive silver ink printed on the conductive carbon paste. There is also provided a sensing device for processing a signal generated by the input device, the sensing device comprising: an operational amplifier to amplify the signal; a filter to filter signal noise from the signal; an adder to apply an offset and attenuation to the signal; a microcontroller comprising an analogue to digital converter to convert the signal into a digital output signal.

Abstract: The present invention relates to Factor IX polypeptides conjugated to heparosan (HEP) polymers, methods for the manufacture thereof and uses of such conjugates. The resultant conjugates may be used—for example—in the treatment or prevention of bleeding disorders such as haemophilia B.