Abstract: A supporting wing structure for an aircraft, in particular for a load-carrying and/or passenger-carrying aircraft, preferably an aircraft in the form of a vertical take-off and landing multicopter having a plurality of electrically driven rotors which are disposed in a distributed manner. The supporting wing structure has a plurality of struts. A first number of the struts are at least largely disposed in a first direction, while a second number of the struts are at least largely disposed in a second direction, the second direction being oriented orthogonal to the first direction. At least the struts of the second number have an aerodynamic profile in cross section, and/or in the struts are connected to one another at least in pairs between neighboring struts by a connecting structure, preferably from individual connecting segments, and the connecting structure or the connecting segments have an aerodynamic profiling. Furthermore an aircraft is provided equipped with such a supporting wing structure.

Abstract: An aircraft with folding mechanism, the aircraft including a fuselage, optionally a payload and/or landing gear attached to the fuselage, at least two longitudinal beams attached to the fuselage that preferably extend parallel to each other and parallel to a first aircraft axis, with lifting units attached to each of the longitudinal beams. At least one crossbeam is attached to the fuselage, and preferably extending parallel to a second aircraft axis and at right angles with respect to the longitudinal beams, with lifting units attached to the crossbeam. The longitudinal beams are rotatably attached to the fuselage by at least one respective first pivot joint configured for pivoting the longitudinal beams around a respective first pivot axis to a pivoted position. The crossbeam is rotatably attached to the fuselage, preferably by at least one second pivot joint, for pivoting the crossbeam around a second pivot axis to a pivoted position.

Abstract: A composite material contains a nonwoven layer (i) which contains fibers formed from a first thermoplastic elastomer having meshes with a mesh size in the range from 10 to 100 ?m, and a membrane layer (ii) which contains a second thermoplastic elastomer and having a layer thickness of less than 30 ?m. The membrane is either pore-free (ii.1) or is porous and has pores with an average pore diameter of less than 2000 nm (ii.2). The membrane (ii) is at least partially in direct contact with the fibers of the nonwoven layer (i) and covers the mesh openings in the nonwoven layer (i) at least partially. The fibers of the first nonwoven layer (i) and the membrane (ii) in the contact area are at least partly joined to one another in an interlocking manner.

Abstract: The present invention relates to a solid pharmaceutical preparation of 3-Fluoro-4-[7-methoxy-3-methyl-8-(1-methyl-1H-pyrazol-4-yl)-2-oxo-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl]-benzonitrile, a method of making same, and medical uses thereof.

Abstract: The present disclosure relates to an injection device. The injection device comprises a body for holding a syringe having a needle extending from one end thereof and a cap that is removably attached to the body. The cap has a needle shield to cover said needle. The injection device further comprises a biasing member and a lock. The biasing member is configured to urge at least a part of the cap away from the body. The lock is moveable between a locked state, wherein the lock holds the cap and body together, and an unlocked state, wherein the cap and body are able to move apart.

Abstract: An injection device comprising: a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end, wherein the distal end is intended to be applied against an injection site; a driving mechanism arranged between the piston and the proximal end of the housing; and a locking mechanism comprising a plate member arranged between the driving mechanism and the piston to retain the driving mechanism to retain the driving mechanism in an initial inactive state in which the driving mechanism cannot be actuated; wherein when the locking mechanism is released, the driving mechanism can be actuated to push the piston towards the distal end of the housing to displace the medicament.

Abstract: The present disclosure relates to a drug delivery device that has a housing and a cap. The drug delivery device also has a lock that prevents the cap being fully replaced on the housing after the cap has been removed.

Abstract: A method for changing the shape of a sheet-like workpiece, which has a mould recess formed by reducing the thickness of the material, includes arranging the workpiece on at least two spaced-apart supporting elements of a machine bed, and forming the workpiece into a final shape by step-by-step free bending. The steps of bending a part of the workpiece by lowering an upper die between the supporting elements from a waiting position into a forming position, raising the upper die into the waiting position and moving the position of the workpiece relative to the machine bed in at least one infeed direction are performed repetitively. Before the workpiece is formed into the final shape, a filling element, which is adapted to the mould recess and designed to make up the material thickness, is produced and is arranged in the region of the mould recess. An arrangement is also provided.

Abstract: The present disclosure relates to an injection device. The injection device comprises a body for holding a syringe that has a needle at one end and a cap that is removably attached to the body. The cap has a needle shield to cover said needle. The injection device further comprises a gear assembly comprising a first rotary gear and a first linear gear to engage with the first rotary gear. The gear assembly is configured such that rotation of the first rotary gear drives the first linear gear to urge the needle shield away from the body. An actuator is provided that is configured to rotate the first rotary gear.

Abstract: The present disclosure relates to a drug delivery device that has a housing and a cap. The drug delivery device also has a lock that prevents the cap being fully replaced on the housing after the cap has been removed.

Abstract: A computer-implemented method for performing data integration, the method comprising establishing a connection between a first application and a first remote database, wherein the connection is established using a connection file containing metadata required to establish the connection, requesting, by the first application, data from the first remote database that stores the data in a first format, wherein the metadata is used to determine whether the first application is authorized to access the data in the first remote database, importing the data in the first format from the first remote database, converting, by the first application, the data in the first format to data in a native format that is specific to the first application, and providing the data in the native format to a user of the first application.

Abstract: A method for producing bead foams from foam beads based on thermoplastic elastomers, especially thermoplastic polyurethane, comprises foam beads being wetted with a polar liquid and joined together thermally in a mold via high-frequency electromagnetic radiation, especially microwave radiation, and also the bead foams obtainable therefrom.

Abstract: A storage device for storing a plurality of auto-injectors, the device configured to activate an auto-injector upon removal of the auto-injector from the device.

Abstract: The present disclosure relates to a cap for an injection device. The injection device comprises a body for holding a syringe having a needle extending from an end thereof. The cap is removably attachable to the body. The cap comprises an actuator and a needle shield to cover said needle. The cap further comprises a coupling between the actuator and the needle shield. The coupling is configured such that when the cap is attached to the body of an injection device axial movement of the actuator away from the body causes rotation of the needle shield relative to the body.

Abstract: An auto-injector device comprises a cap removal mechanism which comprises a retractable component which is slidably mounted within a housing of the device, and a cap-removal actuator to push the retractable component out of the housing to remove a cap from the device; a dispense mechanism which comprises a driving element to expel a medicament from the device; and a dispense button which activates the cap removal mechanism when pressed a first time, engages with the dispense mechanism when released, and activates the dispense mechanism when pressed a second time. The dispense mechanism comprises an engaging element configured to engage with the dispense button when the dispense button has been pressed for a first time and released.

Abstract: A battery holding device for an electrically driven aircraft, including a battery holder for accommodating at least one battery, a connection for establishing electrical contact between the at least one battery and an electrical drive of the aircraft, and a primary securing device for locking the at least one battery in the battery holder. The important factor is that the battery holding device includes at least one secondary securing device for locking the at least one battery in the battery holder, wherein the secondary securing device can be closed and released independently of the primary securing device. The invention also relates to a battery system, to an aircraft and to a corresponding method.

Abstract: An auto-injector for delivering a liquid medicament comprising: a housing arranged to contain a syringe and a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end intended to be applied against an injection site, wherein the syringe comprises: a plurality of plunger elements arranged along a length of the syringe between the proximal end of the housing and the piston, each of the plurality of plunger elements having a longitudinal axis; and a cord arranged to connect the plurality of plunger elements, wherein the plunger elements are configured to become aligned along their axes to push the piston towards the distal end to displace the medicament when the cord is acted on by a driving force.

Abstract: A drive unit for a medical device includes a drive unit housing, a drive member retained in the drive unit housing and movable relative to the drive unit housing to drive an operation of the medical device, the drive member includes a coupler output portion configured to be operatively connected to a liquid handling unit, a drive mechanism retained in the drive unit housing, wherein the drive mechanism is coupleable or coupled to the drive member via a mechanism interface and is configured to transfer a driving force or torque to the drive member, and a sealing member provided to establish a sealed interface with the drive member, wherein the sealed interface defines a sealed section of the interior of the drive unit housing, wherein the mechanism interface is arranged within the sealed section and the coupler output portion is arranged outside of the sealed section.

Abstract: An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element.