Patents by Inventor Michael Harter

Michael Harter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200069962
    Abstract: A system for irradiation of a vascular space and its contents is presented. An adapter device having a vascular access end and an optical interface end can include a waveguide affixed within a waveguide lumen and extending outwardly through the vascular access end. The optical interface end includes a tapered terminus configured to engage with a cavity of an optical connector adapter, creating an optical interface between the waveguide of the adapter device and a waveguide of a light or radiation source. The adapter device enables the simultaneous administration of radiation and exogenous fluids to a patient while maintaining the optical interface isolated from any fluids.
    Type: Application
    Filed: November 7, 2019
    Publication date: March 5, 2020
    Inventors: Scot Johnson, Michael Harter, Josef Victor Scheeren
  • Publication number: 20200018914
    Abstract: An optical device for illuminating the vasculature of a mammal using ultraviolet, visible, and/or infrared light is described. The optical device includes an optical fiber encased in a biocompatible sheath, and is dimensioned to lie within an intravascular catheter. When placed within a vascular space and coupled with a suitable light source the optical device illuminates the vascular space and its contents. The faces of the optical fiber are configured to optimize the capture of ultraviolet, visible, and/or infrared light from a light source without the use of active optics.
    Type: Application
    Filed: April 1, 2019
    Publication date: January 16, 2020
    Inventors: Scot Johnson, Michael Harter
  • Patent number: 10512788
    Abstract: A system for irradiation of a vascular space and its contents is presented. An adapter device having a vascular access end and an optical interface end can include a waveguide affixed within a waveguide lumen and extending outwardly through the vascular access end. The optical interface end includes a tapered terminus configured to engage with a cavity of an optical connector adapter, creating an optical interface between the waveguide of the adapter device and a waveguide of a light or radiation source. The adapter device enables the simultaneous administration of radiation and exogenous fluids to a patient while maintaining the optical interface isolated from any fluids.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: December 24, 2019
    Assignee: UVLrx Therapeutics, Inc.
    Inventors: Scot Johnson, Michael Harter, Victor Josef Scheeren
  • Patent number: 10428083
    Abstract: The present application relates to novel thieno[2,3-d]pyrimidine-2,4-dione (“thienouracil”) derivatives bearing a particular type of (azaheterocyclyl)methyl substituent, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of pulmonary and cardiovascular disorders and of cancer.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: October 1, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Michael Härter, Dirk Kosemund, Martina Delbeck, Bernd Kalthof, Pierre Wasnaire, Frank Süβmeier, Klemens Lustig
  • Patent number: 10260468
    Abstract: The present invention provides for a fuel piping arrangement in common rail type fuel supply systems, the supply system comprising at least one common rail and at least one respective injector, wherein the common rail is connected with the at least one injector directly, by means of only one joint.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: April 16, 2019
    Assignee: FPT MOTORENFORSCHUNG AG
    Inventor: Michael Harter
  • Patent number: 10261277
    Abstract: An optical device for illuminating the vasculature of a mammal using ultraviolet, visible, and/or infrared light is described. The optical device includes an optical fiber encased in a biocompatible sheath, and is dimensioned to lie within an intravascular catheter. When placed within a vascular space and coupled with a suitable light source the optical device illuminates the vascular space and its contents. The faces of the optical fiber are configured to optimize the capture of ultraviolet, visible, and/or infrared light from a light source without the use of active optics.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: April 16, 2019
    Assignee: UVLrx Therapeutics, Inc.
    Inventors: Scot Johnson, Michael Harter
  • Publication number: 20180078781
    Abstract: A system for irradiation of a vascular space and its contents is presented. An adapter device having a vascular access end and an optical interface end can include a waveguide affixed within a waveguide lumen and extending outwardly through the vascular access end. The optical interface end includes a tapered terminus configured to engage with a cavity of an optical connector adapter, creating an optical interface between the waveguide of the adapter device and a waveguide of a light or radiation source. The adapter device enables the simultaneous administration of radiation and exogenous fluids to a patient while maintaining the optical interface isolated from any fluids.
    Type: Application
    Filed: November 16, 2017
    Publication date: March 22, 2018
    Inventors: Scot Johnson, Michael Harter, Victor Josef Scheeren
  • Publication number: 20180065981
    Abstract: The present application relates to novel thieno[2,3-d]pyrimidine-2,4-dione (“thienouracil”) derivatives bearing a particular type of (azaheterocyclyl)methyl substituent, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of pulmonary and cardiovascular disorders and of cancer.
    Type: Application
    Filed: March 21, 2016
    Publication date: March 8, 2018
    Inventors: Michael HÄRTER, Dirk KOSEMUND, Martina DELBECK, Bernd KALTHOF, Pierre WASNAIRE, Frank SÜßMEIER, Klemens LUSTIG
  • Patent number: 9827438
    Abstract: A system for irradiation of a vascular space and its contents is presented. An adapter device having a vascular access end and an optical interface end can include a waveguide affixed within a waveguide lumen and extending outwardly through the vascular access end. The optical interface end includes a tapered terminus configured to engage with a cavity of an optical connector adapter, creating an optical interface between the waveguide of the adapter device and a waveguide of a light or radiation source. The adapter device enables the simultaneous administration of radiation and exogenous fluids to a patient while maintaining the optical interface isolated from any fluids.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: November 28, 2017
    Assignee: UVLRX THERAPEUTICS, INC.
    Inventors: Scot Johnson, Michael Harter, Victor Josef Scheeren
  • Patent number: 9814899
    Abstract: Systems and methods for illumination of a vascular space and its contents using an electromagnetic energy source that supplies a plurality of wavelengths ranging from ultraviolet to infrared are shown. Illumination can be performed using multiple wavelengths, simultaneously or sequentially, and can be performed in accordance with a protocol where an initial illumination produces an effect that is at least partially reversed by a subsequent illumination. Illumination protocols can be stored on a database and accessed via a user interface displayed on the electromagnetic energy source. The database can be used to store data related to performance of system components, and such data can be used to override or modify an illumination protocol.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: November 14, 2017
    Assignee: UVLrx Therapeutics, Inc.
    Inventors: Scot Johnson, Michael Harter
  • Publication number: 20170145029
    Abstract: The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.
    Type: Application
    Filed: February 2, 2017
    Publication date: May 25, 2017
    Inventors: Michael HÄRTER, Martina DELBECK, Bernd KALTHOF, Klemens LUSTIG, Niels LINDNER, Raimund KAST, Pierre WASNAIRE, Frank SÜßMEIER
  • Patent number: 9604996
    Abstract: The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: March 28, 2017
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Michael Härter, Martina Delbeck, Bernd Kalthof, Klemens Lustig, Niels Lindner, Raimund Kast, Pierre Wasnaire, Frank Süβmeier
  • Patent number: 9435386
    Abstract: A fluid friction clutch includes a drivable housing having a working chamber and a reservoir, at least one opening between the reservoir and the working chamber configured to provide fluid communication between the reservoir and the working chamber, a driven disk supported for rotation in the working chamber, and a rotor mounted in the reservoir and rotatably coupled to the driven disk for rotation about an axis of rotation, the rotor having a plurality of arms, separated by a plurality of gaps, projecting away from its axis of rotation.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: September 6, 2016
    Assignee: MAHLE International GmbH
    Inventors: Michael Harter, David McDermott
  • Publication number: 20160244461
    Abstract: The present application relates to novel 2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxamide derivatives (“thienouracil”-carboxamides), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases and to their use for the preparation of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of pulmonary and cardiovascular disorders.
    Type: Application
    Filed: October 2, 2014
    Publication date: August 25, 2016
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Michael HÄRTER, Martina DELBECK, Bernd KALTHOF, Klemens LUSTIG, Niels LINDNER, Raimund KAST, Pierre WASNAIRE, Frank SÜßMEIER
  • Patent number: 9394309
    Abstract: The present application relates to novel 1-phenyl-1H-imidazo[1,2-b]pyrazole derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular angiogenic disorders and hyperproliferative disorders, where neovascularization plays a role, such as, for example, neoplastic disorders and tumor disorders. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: July 19, 2016
    Assignees: Bayer Pharma Aktiengesellschaft, Bayer Intellectual Property GmbH
    Inventors: Frank Süβmeier, Mario Lobell, Sylvia Grünewald, Michael Härter, Bernd Buchmann, Joachim Telser, Hannah Jöriβen, Melanie Heroult, Antje Kahnert, Klemens Lustig, Niels Lindner
  • Publication number: 20160102641
    Abstract: The present invention provides for a fuel piping arrangement in common rail type fuel supply systems, the supply system comprising at least one common rail and at least one respective injector, wherein the common rail is connected with the at least one injector directly, by means of only one joint.
    Type: Application
    Filed: June 12, 2014
    Publication date: April 14, 2016
    Inventor: Michael Harter
  • Publication number: 20150018753
    Abstract: Systems and methods for illumination of a vascular space and its contents using an electromagnetic energy source that supplies a plurality of wavelengths ranging from ultraviolet to infrared are shown. Illumination can be performed using multiple wavelengths, simultaneously or sequentially, and can be performed in accordance with a protocol where an initial illumination produces an effect that is at least partially reversed by a subsequent illumination. Illumination protocols can be stored on a database and accessed via a user interface displayed on the electromagnetic energy source. The database can be used to store data related to performance of system components, and such data can be used to override or modify an illumination protocol.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 15, 2015
    Inventors: Scot Johnson, Michael Harter
  • Publication number: 20150011837
    Abstract: An optical device for illuminating the vasculature of a mammal using ultraviolet, visible, and/or infrared light is described. The optical device includes an optical fiber encased in a biocompatible sheath, and is dimensioned to lie within an intravascular catheter. When placed within a vascular space and coupled with a suitable light source the optical device illuminates the vascular space and its contents. The faces of the optical fiber are configured to optimize the capture of ultraviolet, visible, and/or infrared light from a light source without the use of active optics.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 8, 2015
    Inventors: Scot Johnson, Michael Harter
  • Publication number: 20150012072
    Abstract: A system for irradiation of a vascular space and its contents is presented. An adapter device having a vascular access end and an optical interface end can include a waveguide affixed within a waveguide lumen and extending outwardly through the vascular access end. The optical interface end includes a tapered terminus configured to engage with a cavity of an optical connector adapter, creating an optical interface between the waveguide of the adapter device and a waveguide of a light or radiation source. The adapter device enables the simultaneous administration of radiation and exogenous fluids to a patient while maintaining the optical interface isolated from any fluids.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 8, 2015
    Inventors: Scot Johnson, Michael Harter, Victor Josef Scheeren
  • Patent number: D757955
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: May 31, 2016
    Assignee: UVLrx Therapeutics, Inc.
    Inventors: Scot Johnson, Michael Harter