Patents by Inventor Michael Heberlein

Michael Heberlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID FORMS OF A CDK2 INHIBITOR
    Publication number: 20240076287
    Abstract: The invention relates to solid forms of (1R,3S)-3-[3-({[3-(methoxymethyl)-1-methyl-1H-pyrazol-5-yl]carbonyl}amino)-1H-pyrazol-5-yl]cyclopentyl propan-2-ylcarbamate, to pharmaceutical compositions comprising such solid forms, and to use of such solid forms and pharmaceutical compositions for the treatment of cancer.
    Type: Application
    Filed: December 21, 2021
    Publication date: March 7, 2024
    Applicant: PFIZER INC.
    Inventors: Fengjuan CAO, Kevin Francis DEBOYACE, Michael HEBERLEIN
  • Polymorphs of (1S,2S,3S,5R)-3-((6-(Difluoromethyl)-5-Fluoro-1,2,3,4-Tetrahydroisoquinolin-8-YL)OXY)-5-(4-Methyl-7H-Pyrrolo[2,3-D]Pyrimidin-7-YL)Cyclopentane-1,2-DIOL Mono-Hydrochloride
    Publication number: 20230242539
    Abstract: This invention relates to crystalline mono-HCl salt forms of (1S,2S,3S,5R)-3-((6-(difluoromethyl)-5-fluoro-1,2,3,4-tetrahydroisoquinolin-8-yl)oxy)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol, and to compositions and therapeutic uses thereof.
    Type: Application
    Filed: July 8, 2021
    Publication date: August 3, 2023
    Applicant: Pfizer Inc.
    Inventors: Michael Heberlein, Klimentina Dimitrova Pencheva, Michelle Bich Tran-Dubé