Abstract: A system for performing dynamic DIA directs a mass spectrometer to acquire, based on an acquisition schedule that schedules a plurality of acquisition cycles, MS2 spectra of product ions derived from analytes included in a sample as the analytes elute from a separation system. The acquisition schedule specifies, for each acquisition cycle included in the plurality of acquisition cycles, a dynamic precursor m/z range based on an expected elution time of the analytes. The product ions are produced from precursor ions isolated using an isolation window successively positioned throughout the dynamic precursor m/z range during each acquisition cycle. The system detects an elution time shift in the elution time of the analytes as the analytes elute and adjusts the acquisition schedule based on the detected elution time shift.

Abstract: Methods for the rapid detection of the presence or absence of Malaria parasites (including Plasmodium) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Additionally, the assay can be a multiplex assay, to amplify and detect a plurality of Plasmodium targets simultaneously, which offers advantages over singleplex assays. Furthermore, oligonucleotide primers and oligonucleotide probes targeting Malaria parasites (including Plasmodium) and kits are provided that are designed for the detection of Plasmodium, including, but not limited to, the Plasmodium species of P. falciparum, P. vivax, P. ovale, P. knowlesi, and P. malariae. Also described are kits, reaction mixtures, and oligonucleotides (e.g., primer and probe) for the amplification and detection of Malaria parasites (including Plasmodium).

Abstract: An apparatus for producing packaging, in particular composite packaging for liquid foodstuffs, having a cross-sectional area that decreases in the pour-out direction in the gable region. The packaging is composed of a sleeve having a gable region having a plurality of gable faces and a pouring element. The apparatus has at least one rotatable mandrel wheel having a plurality of mandrels for holding the sleeves. Additionally, a method for producing such packaging and a gable press for use with the aforementioned apparatus. In order to allow easier and more cost-effective production, it is proposed that the apparatus has a gable press, assigned to a single mandrel wheel position, for folding the gable region, for connecting all the gable faces of the gable region of the sleeve to the pouring element and for sealing the protruding ears in the same mandrel wheel position.

Abstract: A heating unit is described and illustrated including at least two heating devices for at least partially heating with hot air end areas of package sleeves to be sealed, wherein the heating unit has an air supply device for supplying air to be heated to the heating devices, wherein the heating devices each have a heating element for producing hot air and a nozzle unit for blowing hot air produced in the heating device against the end area of the package sleeve. In order to be able to increase the leak tightness of the sealed end areas of the package sleeves without having to accept an excessive outlay and effort in terms of the equipment and/or in terms of the method for this, it has been proposed that the heating devices are each separately connected to the air supply device by means of at least one holder and are each separately held on the air supply device by means of the at least one holder.

Abstract: The invention relates to a method for forming package bodies open at one end from package sleeves open at both ends for the manufacture of filled packages. In order to allow packages with a cross section which is neither square nor rectangular to be formed more simply and reliably, the package sleeves are kept ready for further processing in a stack, folded flat along at least two folded edges running in the longitudinal direction of the package sleeve, the flat-folded package sleeves are transferred in succession from the stack to a forming station, the package sleeves are unfolded in a forming station and the unfolded package sleeves are, in the forming station, pushed onto a mandrel in order to close, in particular seal, a longitudinal end of the package sleeve.

Abstract: A device for transporting packagings, in particular packagings for foodstuffs, is disclosed. The device may include a frame, at least two pulleys mounted rotatably on the frame, at least one traction means which runs around the pulleys, and a plurality of mounts for receiving the packagings. The mounts may be connected to the traction means. To also allow the packagings to be precisely positioned in the case of long transportation distances, the traction means may be a belt, in particular a synchronous belt. A method for use of a device of this type for transporting packagings for foodstuffs, in particular composite packagings for foodstuffs, is also disclosed.

Abstract: A mandrel wheel for producing packages is illustrated and described, including: a mandrel wheel shaft having a central axis, a plurality of mandrels attached to the mandrel wheel shaft, an inflow for a coolant and an outflow for the coolant. The mandrels form at least one mandrel group, the mandrels of which are arranged in a plane perpendicular to the central axis of the mandrel wheel shaft. Each mandrel has a hollow space for the coolant, which is connected to an inlet and to an outlet separate from it. At least one distribution element is provided, which connects all inlets of a mandrel group to the inflow and which connects all outlets of the same mandrel group to the outflow, so that the mandrels can be cooled more effectively.

Abstract: A method and apparatus controls and/or regulates the evaporator temperature of an air conditioning system in a motor vehicle in cooling mode. When an outside air temperature exceeds a predetermined limit value, the evaporator temperature is controlled and/or regulated to a predetermined minimum evaporator temperature until a predetermined desired temperature in the interior of the vehicle is reached. After reaching the predetermined desired temperature in the interior of the vehicle, the evaporator temperature is increased until a predetermined interior humidity in the vehicle is reached, or the interior temperature is higher than the predetermined desired temperature for the interior of the vehicle.

Abstract: The invention relates to a method for forming package bodies open at one end from package sleeves open at both ends for the manufacture of filled packages. In order to allow packages with a cross section which is neither square nor rectangular to be formed more simply and reliably, the package sleeves are kept ready for further processing in a stack, folded flat along at least two folded edges running in the longitudinal direction of the package sleeve, the flat-folded package sleeves are transferred in succession from the stack to a forming station, the package sleeves are unfolded in a forming station and the unfolded package sleeves are, in the forming station, pushed onto a mandrel in order to close, in particular seal, a longitudinal end of the package sleeve.

Abstract: An apparatus for the pre-folding of carton sleeves includes at least two folding bars for pre-folding the ridge areas and the triangular areas of the carton sleeves, and at least one folding block that can be introduced into the carton sleeves. The folding bars each have at least one contact area for pre-folding the ridge areas. In addition a method and a system are provided for the pre-folding of carton sleeves. In order to achieve a particularly careful and damage-free pre-folding of the carton sleeves, it is proposed to provide at least one back folder for folding back the triangular areas.

Abstract: A device for transporting packagings, in particular packagings for foodstuffs, is disclosed. The device may include a frame, at least two pulleys mounted rotatably on the frame, at least one traction means which runs around the pulleys, and a plurality of mounts for receiving the packagings. The mounts may be connected to the traction means. To also allow the packagings to be precisely positioned in the case of long transportation distances, the traction means may be a belt, in particular a synchronous belt. A method for use of a device of this type for transporting packagings for foodstuffs, in particular composite packagings for foodstuffs, is also disclosed.

Abstract: A heating unit is described and illustrated including at least two heating devices for at least partially heating with hot air end areas of package sleeves to be sealed, wherein the heating unit has an air supply device for supplying air to be heated to the heating devices, wherein the heating devices each have a heating element for producing hot air and a nozzle unit for blowing hot air produced in the heating device against the end area of the package sleeve. In order to be able to increase the leak tightness of the sealed end areas of the package sleeves without having to accept an excessive outlay and effort in terms of the equipment and/or in terms of the method for this, it has been proposed that the heating devices are each separately connected to the air supply device by means of at least one holder and are each separately held on the air supply device by means of the at least one holder.

Abstract: A mandrel wheel for producing packages is illustrated and described, including: a mandrel wheel shaft having a central axis, a plurality of mandrels attached to the mandrel wheel shaft, an inflow for a coolant and an outflow for the coolant. The mandrels form at least one mandrel group, the mandrels of which are arranged in a plane perpendicular to the central axis of the mandrel wheel shaft. Each mandrel has a hollow space for the coolant, which is connected to an inlet and to an outlet separate from it. At least one distribution element is provided, which connects all inlets of a mandrel group to the inflow and which connects all outlets of the same mandrel group to the outflow, so that the mandrels can be cooled more effectively.

Abstract: An apparatus for producing packaging, in particular composite packaging for liquid foodstuffs, having a cross-sectional area that decreases in the pour-out direction in the gable region. The packaging is composed of a sleeve having a gable region having a plurality of gable faces and a pouring element. The apparatus has at least one rotatable mandrel wheel having a plurality of mandrels for holding the sleeves. Additionally, a method for producing such packaging and a gable press for use with the aforementioned apparatus. In order to allow easier and more cost-effective production, it is proposed that the apparatus has a gable press, assigned to a single mandrel wheel position, for folding the gable region, for connecting all the gable faces of the gable region of the sleeve to the pouring element and for sealing the protruding ears in the same mandrel wheel position.

Abstract: A method for determining the desired ventilation air temperature of an automatic heating and air-conditioning system of a vehicle having an opening top is described. The open or closed state of the top of the vehicle is detected, and the heating and air-conditioning system is controlled and/or regulated in a number of different ways as a function of the state of the top. In the open state of the top, the desired ventilation air temperature is determined as a function of the speed of the vehicle. Also, in the open state of the top the desired ventilation air temperature is determined in such a manner that the top-closed desired ventilation air temperature is increased by a speed-dependent offset value.

Abstract: A method and apparatus controls and/or regulates the evaporator temperature of an air conditioning system in a motor vehicle in cooling mode. When an outside air temperature exceeds a predetermined limit value, the evaporator temperature is controlled and/or regulated to a predetermined minimum evaporator temperature until a predetermined desired temperature in the interior of the vehicle is reached. After reaching the predetermined desired temperature in the interior of the vehicle, the evaporator temperature is increased until a predetermined interior humidity in the vehicle is reached, or the interior temperature is higher than the predetermined desired temperature for the interior of the vehicle.

Abstract: An arrangement for rolling the frontal end of a deformable sleeve-shaped container jacket comprises a supporting surface which radially supports the container jacket in the area of its end. A ring-shaped cavity is arranged radially adjacent thereto, which cavity is closed at the bottom and open at the top. The cavity has an essentially semicircular cross-section. The cavity is provided in circumferential direction with a plurality of pocket-shaped recesses in the transitional area between the supporting surface and the bottom, between which recesses rolling ridges, as part of the original cavity surface, remain. The purpose of this design is to effect a reduction in the deformation forces when the frontal end of the container jacket is being rolled.

Abstract: Shown and described are a device and a method for securing closure films to pouring elements arranged on composite packages with a cyclic or phased conveying device for conveying the closure films, with a feed device, with a welding device, and with a transport device for transporting the composite packages. In order to allow closure films to be secured reliably and rapidly to pouring elements on the composite packages during the manufacturing process, the welding device is arranged above the transport device, the feed device exhibits at least one clamping device for taking up the closure films and is arranged so as to be movable between a take-up position and a welding position, and the take-up position is turned towards the phased conveying device and the welding position is turned towards the transport device.

Abstract: The invention relates to a device and a method for supplying and processing packages arranged on carrier elements, especially drinks packages, using a continuous conveyor belt on which the carrier elements are arranged. The aim of the invention is to be able to further process carrier elements which are continuously supplied by means of a conveyor belt in a processing station in a reliable manner with few technical resources. To this end, two advancing rollers are provided to the right and to the left of the conveyor belt, the rotational axes thereof being perpendicular to the plane of the conveyor belt; two rotating clock belts are provided in the running direction of the conveyor belt, behind the advancing rollers; said clock belts rotate in a plane parallel to the plane of the conveyor belt, and respectively comprise a strand facing the other clock belt; and the strands facing each other run parallel to each other, at a distance corresponding to the width of the carrier elements.

Abstract: The invention is directed to a device for dispensing and observing the luminescence of individual specimens in multi-specimen arrangements, particularly for the examination of biological, chemical or cytobiological assays with high specimen throughput. It is the object of the invention to find a novel possibility for dispensing in multi-specimen arrangements (microplates) and for observing the luminescence of the individual specimens, particularly for examining biological assays with high specimen throughput, which permits an immediate observation of the course of luminescence while dispensing proceeds at the same time without being limited to a determined type of microplate.