Patents by Inventor Michael Hejna

Michael Hejna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue engineered cartilage for drug discovery
    Publication number: 20030138873
    Abstract: A culture system and method for determining the effect of a test agent on the development, homeostasis or degradation of engineered cartilage tissue. The engineered cartilage tissue is obtained by isolating chondrogenic cells and culturing them to obtain chondrocytes in a cell-associated matrix. The chondrocytes and cell associated matrix are then cultured on a semipermeable membrane to provide the engineered cartilage tissue. The engineered tissue, or one of its precursors, can be contacted with the test agent to determine what effect, if any, the test agent has on engineered cartilage.
    Type: Application
    Filed: January 22, 2002
    Publication date: July 24, 2003
    Inventors: Koichi Masuda, Eugene J-M.A. Thonar, Brian Pfister, Michael Hejna
  • Cartilage matrix and in vitro production of transplantable cartilage tissue
    Patent number: 6451060
    Abstract: The present invention is directed to a transplantable cartilage matrix and a method for its in vitro production. In accordance with the method, chondrocytes are cultered for an amount of time effective for allowing formation of a chondrogenic cell-associated matrix. Chondrogenic cells, each with a cell-associated matrix, are recovered and cultured on a semipermeable membrane for a time effective for formation of a cohesive cartilage matrix.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: September 17, 2002
    Assignee: Rush-Presbyterian-St. Luke's Medical Center
    Inventors: Koichi Masuda, Eugene J-M. A. Thomar, Michael Hejna
  • In vitro production of transplantable cartilage tissue
    Publication number: 20010012965
    Abstract: The present invention is directed to a transplantable cartilage matrix and a method for its in vitro production.
    Type: Application
    Filed: March 5, 2001
    Publication date: August 9, 2001
    Applicant: Rush-Presbyterian-St. Luke's Medical Center
    Inventors: Koichi Masuda, Eugene J-M. A. Thomar, Michael Hejna
  • In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage
    Patent number: 6197061
    Abstract: The present invention is directed to a transplantable cartilage matrix and a method for its in vitro production.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: March 6, 2001
    Inventors: Koichi Masuda, Eugene J-M. A. Thonar, Michael Hejna