Abstract: An example system includes one or more non-transitory machine-readable media and one or more processors. The non-transitory machine-readable media is configured to store data and instructions, in which the data includes image data having a plurality of image frames of an electrophoresis process performed on a sample over a time interval. The sample contains at least one analyte. The one or more processors are configured to access the data and execute the instructions, in which the instructions programmed to perform a method. The method can include determining values of pixels within a region of interest (ROI) of respective image frames in the time interval. The method can also include analyzing the determined pixel values for at least some of the respective image frames. The method can also include estimating a quantity of the at least one analyte in the sample based on the analysis of the pixel values.

Abstract: In a disclosed example, a computer-implemented method includes storing image data that includes an input image of a blood sample within a blood monitoring device. The method also includes generating, by a machine learning model, a segmentation mask that assigns pixels in the input image to one of a plurality of classes, which correlate to respective known biophysical properties of blood cells. The method also includes extracting cell images from the input image based on the segmentation mask, in which each extracted cell image includes a respective cluster of the pixels assigned to a respective one of the plurality of classes.

Abstract: An optical coating includes a first resonator with a broadband light absorber. A second resonator includes a narrowband light absorber which is disposed adjacent to and optically coupled to the broadband light absorber. The phase of light reflected from the first resonator slowly varies as a function of wavelength compared to the rapid phase change of the second resonator which exhibits a phase jump within the bandwidth of the broadband light absorber. A thin film optical beam spitter filter coating is also described.

Abstract: Disclosed herein are optical sensor platform(s) employing hyperbolic metamaterial(s) supporting highly confined bulk plasmon guided modes over broad wavelength range(s) from visible to near-infrared. By exciting these modes using—for example—a two-dimensional (2D) grating-coupling technique, sensors according to the present disclosure advantageously exhibit extreme sensitivity modes up to a maximum of 30,000 nm per refractive index unit and a record figure of merit of 590 thereby permitting detection of ultralow-molecular-weight bio-molecules at picomolar concentrations.

Abstract: Disclosed herein are optical sensor platform(s) employing hyperbolic metamaterial(s) supporting highly confined bulk plasmon guided modes over broad wavelength range(s) from visible to near-infrared. By exciting these modes using—for example—a two-dimensional (2D) grating-coupling technique, sensors according to the present disclosure advantageously exhibit extreme sensitivity modes up to a maximum of 30,000 nm per refractive index unit and a record figure of merit of 590 thereby permitting detection of ultralow-molecular-weight bio-molecules at picomolar concentrations.