Patents by Inventor Michael Hockley

Michael Hockley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indeno[1,2-C]pyrazole derivatives for inhibiting tyrosine kinase activity
    Patent number: 6534655
    Abstract: Chemical compounds that are derivatives of indeno[1,2-c]pyrazole are inhibitors of tyrosine kinase activity. Several of the tyrosine kinases, whose activity is inhibited by these chemical compounds, are involved in angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell proliferation is a factor. Compounds of this invention also inhibit the induction of vascular hyperpermeability and the associated formation of edema, ascites, and exudates.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: March 18, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Lee D. Arnold, Yajun Xu, Teresa Barlozzari, Paul Rafferty, Michael Hockley, Allyson Turner
  • Tricyclic pyrazole derivatives
    Patent number: 6462036
    Abstract: This invention relates to certain 3-aryl or 3-heteroaryl pyrazoles with 4,5(3,4)-bicyclic ring fusion which are inhibitors of protein kinase activity, of which some are novel compounds, to pharmaceutical compositions containing these pyrazoles and to processes for preparing these pyrazoles.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: October 8, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Kevin J. Doyle, Paul Rafferty, Robert W. Steele, David J. Wilkins, Lee D. Arnold, Michael Hockley, Anna M. Ericsson, Nobuhiko Iwasaki, Nobuo Ogawa