Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TRENT-1 signaling, wherein the antibodies do not bind to one or more Fc?Rs and do not induce the myeloid cells to produce inflammatory cytokines. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TRENT-1 signaling, wherein the antibodies do not bind to one or more Fc?Rs and do not induce the myeloid cells to produce inflammatory cytokines. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.

Abstract: An electric propulsion module coupled to a spacecraft capable of providing thrust at a level required for multi-burn orbit transfer is disclosed herein. The electric propulsion system includes an electric propulsion thruster, a propellant tank and an energy storage device. In one form the energy storage device is a battery operable to provide sufficient power to maneuver the spacecraft quickly to avoid space debris and/or move to a different orbit through a multi-burn thrust procedure.

Abstract: Wellbore synthesis techniques are disclosed suitable for use in geothermal applications. Embodiments are provided where open hole drilled wellbores are sealed while drilling in sequenced operations with utilization of phase change materials to form an impervious layer at the wellbore/formation interface in high temperature applications. The techniques may be chemical, thermal, mechanical, biological and are fully intended to irreversibly damage the formation in terms of the permeability thereof. With the permeability negated, the wellbore may be used to create a closed loop surface to surface geothermal well operable in the absence of well casing for heat transfer surfaces for maximizing thermal transfer to a circulating working fluid. Formulations for the working and drilling fluids are disclosed.

Abstract: A variator for a mechanical transmission system is disclosed. Transfer means are in rolling contact with input and output members of the variator to transfer rotary motion between them. The input member is coupled to the variator input through a first biasing device arranged to exert a first biasing force on the variator according to a first, input gain which relates input torque acting on the input member and the first biasing force. The output member is coupled to the variator output through a second biasing device arranged to exert a second biasing force on the variator according to a second, output gain which relates output torque acting on the output member and the second biasing force. The first and second biasing forces clamp the variator to provide traction. The first, input gain and second, output gain are different, which, at least in specific variator applications, optimises the traction coefficient.

Abstract: A system for automating design of a support frame for artificial rockwork structures. The system includes a processor and memory storing a three dimensional (3D) mesh for an exterior surface of a rockwork structure. The system includes an offset module that is code/instructions or software executed by the processor to process the 3D mesh and generate an offset mesh defining a 3D topology of the exterior surface at an offset distance from the 3D mesh. The system also includes a chip-defining module including software executed by the processor to divide the offset mesh into a plurality of subsections. The system further includes a rebar line-defining module with software executed by the processor to generate an assembly of rebar pieces for each of the subsections that defines for each of the rebar pieces a length, a location within the subsection, and a set of spaced apart bends.

Abstract: Methods for drilling in higher temperature rock formations such as geothermal formations with phase change material augmented drilling fluid are disclosed. By observing flow rate of the augmented fluid, heat exchange between the annulus returning fluid and tubular fluid can be minimized thereby facilitating a cooler fluid for contact with a rock face being drilled. The cooling assists in pre-fracturing the rock face prior to destruction by the drill bit.

Abstract: An apparatus including a channel having open channel ends, a pair of channel sidewalls extending from a channel web, and a pair of linear ribs inwardly protruding from the pair of channel sidewalls, the pair of ribs configured to slidably engage a pair of grooves disposed in a tool holder.

Abstract: A system for automating design of a support frame for artificial rockwork structures. The system includes a processor and memory storing a three dimensional (3D) mesh for an exterior surface of a rockwork structure. The system includes an offset module that is code/instructions or software executed by the processor to process the 3D mesh and generate an offset mesh defining a 3D topology of the exterior surface at an offset distance from the 3D mesh. The system also includes a chip-defining module including software executed by the processor to divide the offset mesh into a plurality of subsections. The system further includes a rebar line-defining module with software executed by the processor to generate an assembly of rebar pieces for each of the subsections that defines for each of the rebar pieces a length, a location within the subsection, and a set of spaced apart bends.

Abstract: Methods and systems for identifying an object in content and determining information associated with the object are provided. A device can be used to select a region comprising an object of interest in content (e.g., video, streaming content). The object of interest can be an object (e.g., an actor, a landmark, text, etc.) a user observes during consumption of the content. The selected region can be defined by temporal and coordinate information associated with the content. The information associated with the content can be analyzed to identify the content, extract an image from the content, identify the object of interest and provide additional information.

Abstract: A wagering game system and its operations are described herein. In embodiments, the operations can include determining a bank gaming effect for presentation on a bank of content presentation devices. The bank of content presentation devices can be associated with a plurality of wagering game machines. The operations can further include receiving presentation status information for the bank of content presentation devices. The presentation status information can indicate one or more events that affect a state of availability of each of the bank of content presentation devices to present the bank gaming effect. The operations can further include determining, based on the presentation status information, one content presentation device, from the bank of content presentation devices, that is ineligible to present the bank gaming effect. The operations can also include excluding the one content presentation device from participation in the bank gaming effect.

Abstract: A variator for a mechanical transmission system is disclosed. Transfer means are in rolling contact with input and output members of the variator to transfer rotary motion between them. The input member is coupled to the variator input through a first biasing device arranged to exert a first biasing force on the variator according to a first, input gain which relates input torque acting on the input member and the first biasing force. The output member is coupled to the variator output through a second biasing device arranged to exert a second biasing force on the variator according to a second, output gain which relates output torque acting on the output member and the second biasing force. The first and second biasing forces clamp the variator to provide traction. The first, input gain and second, output gain are different, which, at least in specific variator applications, optimises the traction coefficient.

Abstract: A tool for removing snow and ice from horse hooves is provided. The tool includes a handle to fit into the hand of the user and a head secured to the end of the handle. The head is comprised of a spoon like end for primary debris removal and a hoof pick end for additional debris removal. The spoon like end has a machined edge to facilitate cutting into and breaking up the snow and ice buildup. The rounded shape of the spoonlike end prevents injury to the horse's hoof.

Abstract: A wagering game system and its operations which can include analyzing electronic information associated with a first gaming effect and a second gaming effect provided for concurrent presentation via an output device, determining that the first gaming effect has a higher priority than the second gaming effect, and causing the first gaming effect to be presented via the output device before the second gaming effect is presented based on the higher priority. The operations can further include preventing, without user input, presentation of a first portion of the second amine effect via the output device while the first gaming effect is presented. The operations can further include electronically determining that a second portion of the second gaming effect is available for presentation after an ending point for the first gaming effect, and causing the second portion to be presented via the output device after the first gaming effect.

Abstract: A wagering game system and its operations are described herein. In some examples, the operations can include receiving emotive light presentation data from a variety of emotive light control sources and determining presentation priorities for the emotive light presentation data. The operations can further include controlling the emotive light presentation data, from the variety of emotive light control sources, based on prioritization of the presentation priorities. In some embodiments, the operations can include controlling priorities based on locations of emotive lighting devices on a wagering game machine. In other embodiments, the operations can include assigning priorities based on wagering game types and other classifications. In yet other embodiments, the operations can utilize priority values to determine lighting prominence, which in conjunction with transparency values, can generate blended, or composite lighting effects.

Abstract: A wagering game system and its operations are described herein. In some embodiments, the operations can include receiving emotive light presentation data from a variety of emotive light control sources and determining presentation priorities for the emotive light presentation data. The operations can further include controlling the emotive light presentation data, from the variety of emotive light control sources, based on prioritization of the presentation priorities. In some embodiments, the operations can include controlling priorities based on locations of emotive lighting devices on a wagering game machine. In other embodiments, the operations can include assigning priorities based on wagering game types and other classifications. In yet other embodiments, the operations can utilize priority values to determine lighting prominence, which in conjunction with transparency values, can generate blended, or composite lighting effects.

Abstract: A portable ventilator uses a ROOTS-type blower as a compressor to reduce both the size and power consumption of the ventilator. Various functional aspects of the ventilator are delegated to multiple subassemblies having dedicated controllers and software that interact with a ventilator processor to provide user interface functions, exhalation control and flow control servos, and monitoring of patient status. The ventilator overcomes noise problems through the use of noise reducing pressure compensating orifices on the ROOTS-type blower housing and multiple baffling chambers. The ventilator is configured with a highly portable form factor, and may be used as a stand-alone device or as a docked device having a docking cradle with enhanced interface and monitoring capabilities.

Abstract: A method and apparatus for controlling a brushless DC (BLDC) motor over a wide range of angular speeds is presented. Analog magnetic sensors provide continuous signal measurements related to the rotor angular position at a sample rate independent of rotor angular speed. In one embodiment, analog signal measurements are subsequently processed using an arctangent function to obtain the rotor angular position. The arctangent may be computed using arithmetic computation, a small angle approximation, a polynomial evaluation approach, a table lookup approach, or a combination of various methods. In one embodiment, the BLDC rotor is used to drive a Roots blower used as a compressor in a portable mechanical ventilator system.

Abstract: A portable ventilator uses a Roots-type blower as a compressor to reduce both the size and power consumption of the ventilator. Various functional aspects of the ventilator are delegated to multiple subassemblies having dedicated controllers and software that interact with a ventilator processor to provide user interface functions, exhalation control and flow control servos, and monitoring of patient status. The ventilator overcomes noise problems through the use of noise reducing pressure compensating orifices on the Roots blower housing and multiple baffling chambers. The ventilator is configured with a highly portable form factor, and may be used as a stand-alone device or as a docked device having a docking cradle with enhanced interface and monitoring capabilities.

Abstract: A portable ventilator uses a ROOTS-type blower as a compressor to reduce both the size and power consumption of the ventilator. Various functional aspects of the ventilator are delegated to multiple subassemblies having dedicated controllers and software that interact with a ventilator processor to provide user interface functions, exhalation control and flow control servos, and monitoring of patient status. The ventilator overcomes noise problems through the use of noise reducing pressure compensating orifices on the ROOTS-type blower housing and multiple baffling chambers. The ventilator is configured with a highly portable form factor, and may be used as a stand-alone device or as a docked device having a docking cradle with enhanced interface and monitoring capabilities.