Patents by Inventor Michael Holtz

Michael Holtz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230365618
    Abstract: Crystalline forms of thiocholesterol are disclosed herein. Such forms include crystalline Form thiocholesterol, crystalline Form B thiocholesterol, crystalline thiocholesterol Form C. Processes for making crystalline thiocholesterol, pharmaceutical compositions comprising crystalline thiocholesterol, methods of treatment comprising administering crystalline thiocholesterol, including ctystalline thiocholesterol Form A, crystalline thiocholesterol Form B, and/or crystalline thiocholesterol Form C are further provided.
    Type: Application
    Filed: October 11, 2021
    Publication date: November 16, 2023
    Inventors: ANDREW R. MIKSZTAL, WEIQI LIN, MICHAEL HOLTZ-MULHOLLAND, JULIETTE SABBATANI, TRAVIS LEE HOUSTON, STEPHAN D. PARENT
  • Publication number: 20230357308
    Abstract: Crystalline and non-crystalline forms of crystalline sodium cholesteryl sulfonate are disclosed herein. Such forms include crystalline sodium sulfonate Form F and crystalline sodium cholesteryl sulfonate Form J as well as non-crystalline sodium cholesteryl sulfonate Form A. Processes for making such crystalline and non-crystalline forms and methods of treating disease with such forms are further provided.
    Type: Application
    Filed: October 11, 2021
    Publication date: November 9, 2023
    Inventors: WEIQI LIN, MICHAEL HOLTZ-MULHOLLAND, JULIETTE SABBATANI, JING TENG
  • Publication number: 20230056273
    Abstract: Crystalline and liquid crystalline forms of 25HC3S sodium are described herein. The disclosure includes Forms I, II, III, V, IX, XI, and XIII of 25HC3S sodium and combinations thereof. Pharmaceutical formulations of said forms, or combinations thereof, and methods of treating or preventing disease such as hypercholesterolemia, hypertriglyceridemia, and conditions related to fat accumulation and inflammation (e.g., non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), alcoholic hepatitis, acute kidney injury (AKI), psoriasis, and atherosclerosis) are further disclosed herein.
    Type: Application
    Filed: December 23, 2020
    Publication date: February 23, 2023
    Inventors: ANDREW R. MIKSZTAL, SHAWN JOHNSTONE, MICHAEL HOLTZ-MULHOLLAND, FLAVIO LOPEZ, HOWARD SARD, JIE LI, MARIO GONZALEZ, STEPHAN D. PARENT, TRAVIS LEE HOUSTON, ROBERT WENSLOW
  • Publication number: 20220036265
    Abstract: Methods, computer systems, computer-storage media, and graphical user interfaces are provided for enhancing remote work productivity data. In one embodiment, worker data is obtained for a set of target workers and a set of control workers. The target workers are generally identified as working in the office prior to a treatment date and working remote after a treatment date, and the control workers are generally identified as working remote before and after the treatment date. Thereafter, an effect of working remotely is determined using a difference-in-differences model that measures differences in observational changes between the set of target workers and the set of control workers measured before and after the treatment date. The effect of working remotely can be used to generate a generating a productivity score indicating an extent of productivity in relation to the set of target workers.
    Type: Application
    Filed: July 29, 2020
    Publication date: February 3, 2022
    Inventors: Longqi YANG, Sonia Patricia JAFFE, David Michael HOLTZ, Siddharth SURI, Shilpi SINHA, Jeffrey Michael WESTON, Connor Michael JOYCE, Neha Parikh SHAH, Kevin Scott SHERMAN, Chia-Jung LEE, Brent Jaron HECHT, Jaime TEEVAN
  • Patent number: 10664855
    Abstract: This disclosure includes methods for predicting demand based on the price of a time-expiring inventory. An online system provides a connection between a manager of a time-expiring inventory and a plurality of clients. The online system provides a listing for the manager's time-expiring inventory to clients on the online system. The manager specifies the price of the time-expiring inventory in the listing. A demand function predicts the demand for the time-expiring inventory based on features of the listing and the time-expiring inventory. The online system determines a likelihood of receiving a request for the time-expiring inventory from a client on the online system based on the predicted demand. The online system may use the determined likelihoods to provide to the manager information about how changes in the price of the listing are likely to affect the demand for the time-expiring inventory.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: May 26, 2020
    Assignee: Airbnb, Inc.
    Inventors: Bar Ifrach, David Michael Holtz, Yangli Hector Yee, Li Zhang
  • Patent number: 10614385
    Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: April 7, 2020
    Assignee: Airbnb, Inc.
    Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
  • Publication number: 20180357576
    Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.
    Type: Application
    Filed: August 21, 2018
    Publication date: December 13, 2018
    Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
  • Patent number: 10083405
    Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: September 25, 2018
    Assignee: Airbnb, Inc.
    Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
  • Publication number: 20160247093
    Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.
    Type: Application
    Filed: February 20, 2015
    Publication date: August 25, 2016
    Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
  • Publication number: 20160148237
    Abstract: This disclosure includes methods for predicting demand based on the price of a time-expiring inventory. An online system provides a connection between a manager of a time-expiring inventory and a plurality of clients. The online system provides a listing for the manager's time-expiring inventory to clients on the online system. The manager specifies the price of the time-expiring inventory in the listing. A demand function predicts the demand for the time-expiring inventory based on features of the listing and the time-expiring inventory. The online system determines a likelihood of receiving a request for the time-expiring inventory from a client on the online system based on the predicted demand. The online system may use the determined likelihoods to provide to the manager information about how changes in the price of the listing are likely to affect the demand for the time-expiring inventory.
    Type: Application
    Filed: November 25, 2015
    Publication date: May 26, 2016
    Inventors: Bar Ifrach, David Michael Holtz, Yangli Hector Yee, Li Zhang
  • Publication number: 20080064966
    Abstract: Endocardial pressure measurement devices, systems and methods for the effective treatment of congestive heart failure and its underlying causes, in addition to other clinical applications.
    Type: Application
    Filed: March 22, 2007
    Publication date: March 13, 2008
    Applicant: Transoma Medical, Inc.
    Inventors: Brian Brockway, Gregory Doten, Michael Holtz, Michael Kalm, Scott Kuehn, Scott Lambert, Gregg Lichtscheidl, Perry Mills, Oleg Mosesov, Demetre Nicoloff, Karen Odden, Soon Park, Christopher Quinn, Alyse Stofer, Jeff Taylor, Justin Van Hee, Lynn Zwiers, Dan Huetteman, Dave Lodin, Jeremy Riedesel
  • Patent number: 7289928
    Abstract: The present device relates to a method of improving a indirect measurement tire pressure detection system. Such systems include a system that detects pressure loss based on wheel speed data. The present method determines reference values dependent upon driving parameters and produces a two-dimensional or multi-dimensional closed range of driving parameters. The closed range of driving parameters uses reference values that are determined to be currently valid.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: October 30, 2007
    Assignee: Continental Teves A.G. & Co., OHG
    Inventors: Martin Griesser, Andreas Köbe, Frank Edling, Michael Holtz, Karl Perras
  • Patent number: 7263878
    Abstract: The present invention relates to a method of detecting growth of the dynamic tire circumference (circumferential growth or tire growth), wherein at least one reference value Ref is produced on the basis of wheel speed information, said reference value representing in particular a sidewise and/or crosswise relation of the motor vehicle wheels, and wherein the time variation of the reference value(s) is examined and, further, tire growth is detected on the basis of said variation.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: September 4, 2007
    Assignee: Continental Teves AG & Co. oHG
    Inventors: Martin Griesser, Andreas Köbe, Frank Edling, Michael Holtz, Karl Perras
  • Publication number: 20060155505
    Abstract: The present device relates to a method of improving a indirect measurement tire pressure detection system. Such systems include a system that detects pressure loss based on wheel speed data. The present method determines reference values dependent upon driving parameters and produces a two-dimensional or multi-dimensional closed range of driving parameters. The closed range of driving parameters uses reference values that are determined to be currently valid.
    Type: Application
    Filed: December 5, 2003
    Publication date: July 13, 2006
    Inventors: Martin Griesser, Andreas Kobe, Frank Edling, Michael Holtz, Karl Perras
  • Patent number: 7003846
    Abstract: A vacuum and disposal system for the collection and disposal of animal feces. The vacuum and disposal system consists of a vacuum source, a vacuum tube, a flexible hose, and an intake tube. The vacuum is provided by an electric motor powered by a rechargeable battery and is used to create a vacuum or suction through the vacuum tube, the flexible hose, and the intake tube to collect the animal feces. A cartridge having a filter is inserted into the intake tube to receive the animal feces collected. After collection, the vacuum and disposal system is converted to an unload position for the removal of the cartridge from the intake tube and the ultimate disposal of the animal feces. Alternatively, a compact vacuum and disposal system may be used in smaller areas.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: February 28, 2006
    Assignee: Holtz Engineering, Ltd.
    Inventor: Carl Michael Holtz
  • Publication number: 20050126274
    Abstract: The present invention relates to a method of detecting growth of the dynamic tire circumference (circumferential growth or tire growth), wherein at least one reference value Ref is produced on the basis of wheel speed information, said reference value representing in particular a sidewise and/or crosswise relation of the motor vehicle wheels, and wherein the time variation of the reference value(s) is examined and, further, tire growth is detected on the basis of said variation.
    Type: Application
    Filed: April 11, 2003
    Publication date: June 16, 2005
    Inventors: Martin Griesser, Andreas Kobe, Frank Edling, Michael Holtz, Karl Perras
  • Publication number: 20040194248
    Abstract: A vacuum and disposal system for the collection and disposal of animal feces. The vacuum and disposal system consists of a vacuum source, a vacuum tube, a flexible hose, and an intake tube. The vacuum is provided by an electric motor powered by a rechargeable battery and is used to create a vacuum or suction through the vacuum tube, the flexible hose, and the intake tube to collect the animal feces. A cartridge having a filter is inserted into the intake tube to receive the animal feces collected. After collection, the vacuum and disposal system is converted to an unload position for the removal of the cartridge from the intake tube and the ultimate disposal of the animal feces. Alternatively, a compact vacuum and disposal system may be used in smaller areas.
    Type: Application
    Filed: April 1, 2003
    Publication date: October 7, 2004
    Inventor: Carl Michael Holtz
  • Publication number: 20020120200
    Abstract: Endocardial pressure measurement devices, systems and methods for the effective treatment of congestive heart failure and its underlying causes, in addition to other clinical applications.
    Type: Application
    Filed: February 15, 2002
    Publication date: August 29, 2002
    Inventors: Brian Brockway, Gregory Doten, Michael Holtz, Michael L. Kalm, Scott Kuehn, Scott Lambert, Gregg Lichtscheidl, Perry Mills, Oleg Mosesov, Demetre M. Nicoloff, Karen Odden, Soon Park, Christopher Quinn, Alyse Stofer, Jeff Taylor, Justin VanHee, Lynn Zwiers
  • Patent number: 5706319
    Abstract: A reactor vessel seal for temporarily sealing a reactor pressure vessel from a water-filled refueling canal above the reactor pressure vessel. The reactor vessel seal is installed in place of the removable reactor pressure vessel closure head for inspecting/servicing the reactor vessel. The reactor seal comprises a seal cap having a surface connected to a flange which is complementary to the upper flange of the reactor pressure vessel. A seal is located between the seal cap flange and the upper flange of the reactor pressure vessel. A lifting rig is connected to the seal cap for lifting the seal cap and placing it in position, with the seal cap flange in alignment with the reactor vessel upper flange, such that the seal located between the seal cap flange and the reactor pressure vessel upper flange is compressed by hydrostatic pressure from water in the water-filled refueling canal acting on the surface of the seal cap as water in the reactor pressure vessel is evacuated.
    Type: Grant
    Filed: August 12, 1996
    Date of Patent: January 6, 1998
    Assignee: Joseph Oat Corporation
    Inventor: Michael Holtz