Patents by Inventor Michael Holtz
Michael Holtz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230365618Abstract: Crystalline forms of thiocholesterol are disclosed herein. Such forms include crystalline Form thiocholesterol, crystalline Form B thiocholesterol, crystalline thiocholesterol Form C. Processes for making crystalline thiocholesterol, pharmaceutical compositions comprising crystalline thiocholesterol, methods of treatment comprising administering crystalline thiocholesterol, including ctystalline thiocholesterol Form A, crystalline thiocholesterol Form B, and/or crystalline thiocholesterol Form C are further provided.Type: ApplicationFiled: October 11, 2021Publication date: November 16, 2023Inventors: ANDREW R. MIKSZTAL, WEIQI LIN, MICHAEL HOLTZ-MULHOLLAND, JULIETTE SABBATANI, TRAVIS LEE HOUSTON, STEPHAN D. PARENT
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Publication number: 20230357308Abstract: Crystalline and non-crystalline forms of crystalline sodium cholesteryl sulfonate are disclosed herein. Such forms include crystalline sodium sulfonate Form F and crystalline sodium cholesteryl sulfonate Form J as well as non-crystalline sodium cholesteryl sulfonate Form A. Processes for making such crystalline and non-crystalline forms and methods of treating disease with such forms are further provided.Type: ApplicationFiled: October 11, 2021Publication date: November 9, 2023Inventors: WEIQI LIN, MICHAEL HOLTZ-MULHOLLAND, JULIETTE SABBATANI, JING TENG
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Publication number: 20230056273Abstract: Crystalline and liquid crystalline forms of 25HC3S sodium are described herein. The disclosure includes Forms I, II, III, V, IX, XI, and XIII of 25HC3S sodium and combinations thereof. Pharmaceutical formulations of said forms, or combinations thereof, and methods of treating or preventing disease such as hypercholesterolemia, hypertriglyceridemia, and conditions related to fat accumulation and inflammation (e.g., non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), alcoholic hepatitis, acute kidney injury (AKI), psoriasis, and atherosclerosis) are further disclosed herein.Type: ApplicationFiled: December 23, 2020Publication date: February 23, 2023Inventors: ANDREW R. MIKSZTAL, SHAWN JOHNSTONE, MICHAEL HOLTZ-MULHOLLAND, FLAVIO LOPEZ, HOWARD SARD, JIE LI, MARIO GONZALEZ, STEPHAN D. PARENT, TRAVIS LEE HOUSTON, ROBERT WENSLOW
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Publication number: 20220036265Abstract: Methods, computer systems, computer-storage media, and graphical user interfaces are provided for enhancing remote work productivity data. In one embodiment, worker data is obtained for a set of target workers and a set of control workers. The target workers are generally identified as working in the office prior to a treatment date and working remote after a treatment date, and the control workers are generally identified as working remote before and after the treatment date. Thereafter, an effect of working remotely is determined using a difference-in-differences model that measures differences in observational changes between the set of target workers and the set of control workers measured before and after the treatment date. The effect of working remotely can be used to generate a generating a productivity score indicating an extent of productivity in relation to the set of target workers.Type: ApplicationFiled: July 29, 2020Publication date: February 3, 2022Inventors: Longqi YANG, Sonia Patricia JAFFE, David Michael HOLTZ, Siddharth SURI, Shilpi SINHA, Jeffrey Michael WESTON, Connor Michael JOYCE, Neha Parikh SHAH, Kevin Scott SHERMAN, Chia-Jung LEE, Brent Jaron HECHT, Jaime TEEVAN
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Patent number: 10664855Abstract: This disclosure includes methods for predicting demand based on the price of a time-expiring inventory. An online system provides a connection between a manager of a time-expiring inventory and a plurality of clients. The online system provides a listing for the manager's time-expiring inventory to clients on the online system. The manager specifies the price of the time-expiring inventory in the listing. A demand function predicts the demand for the time-expiring inventory based on features of the listing and the time-expiring inventory. The online system determines a likelihood of receiving a request for the time-expiring inventory from a client on the online system based on the predicted demand. The online system may use the determined likelihoods to provide to the manager information about how changes in the price of the listing are likely to affect the demand for the time-expiring inventory.Type: GrantFiled: November 25, 2015Date of Patent: May 26, 2020Assignee: Airbnb, Inc.Inventors: Bar Ifrach, David Michael Holtz, Yangli Hector Yee, Li Zhang
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Patent number: 10614385Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.Type: GrantFiled: August 21, 2018Date of Patent: April 7, 2020Assignee: Airbnb, Inc.Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
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Publication number: 20180357576Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.Type: ApplicationFiled: August 21, 2018Publication date: December 13, 2018Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
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Patent number: 10083405Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.Type: GrantFiled: February 20, 2015Date of Patent: September 25, 2018Assignee: Airbnb, Inc.Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
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Publication number: 20160247093Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.Type: ApplicationFiled: February 20, 2015Publication date: August 25, 2016Inventors: Lenny Rachitsky, Martin Anh Dung Nguyen, Vaughn Quoss, David Michael Holtz, Daniel Nathan Hill, James Allen Ostrowski, II, Nelson Aurel Gauthier
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Publication number: 20160148237Abstract: This disclosure includes methods for predicting demand based on the price of a time-expiring inventory. An online system provides a connection between a manager of a time-expiring inventory and a plurality of clients. The online system provides a listing for the manager's time-expiring inventory to clients on the online system. The manager specifies the price of the time-expiring inventory in the listing. A demand function predicts the demand for the time-expiring inventory based on features of the listing and the time-expiring inventory. The online system determines a likelihood of receiving a request for the time-expiring inventory from a client on the online system based on the predicted demand. The online system may use the determined likelihoods to provide to the manager information about how changes in the price of the listing are likely to affect the demand for the time-expiring inventory.Type: ApplicationFiled: November 25, 2015Publication date: May 26, 2016Inventors: Bar Ifrach, David Michael Holtz, Yangli Hector Yee, Li Zhang
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Publication number: 20080064966Abstract: Endocardial pressure measurement devices, systems and methods for the effective treatment of congestive heart failure and its underlying causes, in addition to other clinical applications.Type: ApplicationFiled: March 22, 2007Publication date: March 13, 2008Applicant: Transoma Medical, Inc.Inventors: Brian Brockway, Gregory Doten, Michael Holtz, Michael Kalm, Scott Kuehn, Scott Lambert, Gregg Lichtscheidl, Perry Mills, Oleg Mosesov, Demetre Nicoloff, Karen Odden, Soon Park, Christopher Quinn, Alyse Stofer, Jeff Taylor, Justin Van Hee, Lynn Zwiers, Dan Huetteman, Dave Lodin, Jeremy Riedesel
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Patent number: 7289928Abstract: The present device relates to a method of improving a indirect measurement tire pressure detection system. Such systems include a system that detects pressure loss based on wheel speed data. The present method determines reference values dependent upon driving parameters and produces a two-dimensional or multi-dimensional closed range of driving parameters. The closed range of driving parameters uses reference values that are determined to be currently valid.Type: GrantFiled: December 5, 2003Date of Patent: October 30, 2007Assignee: Continental Teves A.G. & Co., OHGInventors: Martin Griesser, Andreas Köbe, Frank Edling, Michael Holtz, Karl Perras
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Patent number: 7263878Abstract: The present invention relates to a method of detecting growth of the dynamic tire circumference (circumferential growth or tire growth), wherein at least one reference value Ref is produced on the basis of wheel speed information, said reference value representing in particular a sidewise and/or crosswise relation of the motor vehicle wheels, and wherein the time variation of the reference value(s) is examined and, further, tire growth is detected on the basis of said variation.Type: GrantFiled: April 11, 2003Date of Patent: September 4, 2007Assignee: Continental Teves AG & Co. oHGInventors: Martin Griesser, Andreas Köbe, Frank Edling, Michael Holtz, Karl Perras
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Publication number: 20060155505Abstract: The present device relates to a method of improving a indirect measurement tire pressure detection system. Such systems include a system that detects pressure loss based on wheel speed data. The present method determines reference values dependent upon driving parameters and produces a two-dimensional or multi-dimensional closed range of driving parameters. The closed range of driving parameters uses reference values that are determined to be currently valid.Type: ApplicationFiled: December 5, 2003Publication date: July 13, 2006Inventors: Martin Griesser, Andreas Kobe, Frank Edling, Michael Holtz, Karl Perras
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Patent number: 7003846Abstract: A vacuum and disposal system for the collection and disposal of animal feces. The vacuum and disposal system consists of a vacuum source, a vacuum tube, a flexible hose, and an intake tube. The vacuum is provided by an electric motor powered by a rechargeable battery and is used to create a vacuum or suction through the vacuum tube, the flexible hose, and the intake tube to collect the animal feces. A cartridge having a filter is inserted into the intake tube to receive the animal feces collected. After collection, the vacuum and disposal system is converted to an unload position for the removal of the cartridge from the intake tube and the ultimate disposal of the animal feces. Alternatively, a compact vacuum and disposal system may be used in smaller areas.Type: GrantFiled: April 1, 2003Date of Patent: February 28, 2006Assignee: Holtz Engineering, Ltd.Inventor: Carl Michael Holtz
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Publication number: 20050126274Abstract: The present invention relates to a method of detecting growth of the dynamic tire circumference (circumferential growth or tire growth), wherein at least one reference value Ref is produced on the basis of wheel speed information, said reference value representing in particular a sidewise and/or crosswise relation of the motor vehicle wheels, and wherein the time variation of the reference value(s) is examined and, further, tire growth is detected on the basis of said variation.Type: ApplicationFiled: April 11, 2003Publication date: June 16, 2005Inventors: Martin Griesser, Andreas Kobe, Frank Edling, Michael Holtz, Karl Perras
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Publication number: 20040194248Abstract: A vacuum and disposal system for the collection and disposal of animal feces. The vacuum and disposal system consists of a vacuum source, a vacuum tube, a flexible hose, and an intake tube. The vacuum is provided by an electric motor powered by a rechargeable battery and is used to create a vacuum or suction through the vacuum tube, the flexible hose, and the intake tube to collect the animal feces. A cartridge having a filter is inserted into the intake tube to receive the animal feces collected. After collection, the vacuum and disposal system is converted to an unload position for the removal of the cartridge from the intake tube and the ultimate disposal of the animal feces. Alternatively, a compact vacuum and disposal system may be used in smaller areas.Type: ApplicationFiled: April 1, 2003Publication date: October 7, 2004Inventor: Carl Michael Holtz
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Publication number: 20020120200Abstract: Endocardial pressure measurement devices, systems and methods for the effective treatment of congestive heart failure and its underlying causes, in addition to other clinical applications.Type: ApplicationFiled: February 15, 2002Publication date: August 29, 2002Inventors: Brian Brockway, Gregory Doten, Michael Holtz, Michael L. Kalm, Scott Kuehn, Scott Lambert, Gregg Lichtscheidl, Perry Mills, Oleg Mosesov, Demetre M. Nicoloff, Karen Odden, Soon Park, Christopher Quinn, Alyse Stofer, Jeff Taylor, Justin VanHee, Lynn Zwiers
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Patent number: 5706319Abstract: A reactor vessel seal for temporarily sealing a reactor pressure vessel from a water-filled refueling canal above the reactor pressure vessel. The reactor vessel seal is installed in place of the removable reactor pressure vessel closure head for inspecting/servicing the reactor vessel. The reactor seal comprises a seal cap having a surface connected to a flange which is complementary to the upper flange of the reactor pressure vessel. A seal is located between the seal cap flange and the upper flange of the reactor pressure vessel. A lifting rig is connected to the seal cap for lifting the seal cap and placing it in position, with the seal cap flange in alignment with the reactor vessel upper flange, such that the seal located between the seal cap flange and the reactor pressure vessel upper flange is compressed by hydrostatic pressure from water in the water-filled refueling canal acting on the surface of the seal cap as water in the reactor pressure vessel is evacuated.Type: GrantFiled: August 12, 1996Date of Patent: January 6, 1998Assignee: Joseph Oat CorporationInventor: Michael Holtz