Abstract: Crystalline forms of thiocholesterol are disclosed herein. Such forms include crystalline Form thiocholesterol, crystalline Form B thiocholesterol, crystalline thiocholesterol Form C. Processes for making crystalline thiocholesterol, pharmaceutical compositions comprising crystalline thiocholesterol, methods of treatment comprising administering crystalline thiocholesterol, including ctystalline thiocholesterol Form A, crystalline thiocholesterol Form B, and/or crystalline thiocholesterol Form C are further provided.

Abstract: Crystalline and non-crystalline forms of crystalline sodium cholesteryl sulfonate are disclosed herein. Such forms include crystalline sodium sulfonate Form F and crystalline sodium cholesteryl sulfonate Form J as well as non-crystalline sodium cholesteryl sulfonate Form A. Processes for making such crystalline and non-crystalline forms and methods of treating disease with such forms are further provided.

Abstract: Crystalline and liquid crystalline forms of 25HC3S sodium are described herein. The disclosure includes Forms I, II, III, V, IX, XI, and XIII of 25HC3S sodium and combinations thereof. Pharmaceutical formulations of said forms, or combinations thereof, and methods of treating or preventing disease such as hypercholesterolemia, hypertriglyceridemia, and conditions related to fat accumulation and inflammation (e.g., non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), alcoholic hepatitis, acute kidney injury (AKI), psoriasis, and atherosclerosis) are further disclosed herein.

Abstract: Methods, computer systems, computer-storage media, and graphical user interfaces are provided for enhancing remote work productivity data. In one embodiment, worker data is obtained for a set of target workers and a set of control workers. The target workers are generally identified as working in the office prior to a treatment date and working remote after a treatment date, and the control workers are generally identified as working remote before and after the treatment date. Thereafter, an effect of working remotely is determined using a difference-in-differences model that measures differences in observational changes between the set of target workers and the set of control workers measured before and after the treatment date. The effect of working remotely can be used to generate a generating a productivity score indicating an extent of productivity in relation to the set of target workers.

Abstract: This disclosure includes methods for predicting demand based on the price of a time-expiring inventory. An online system provides a connection between a manager of a time-expiring inventory and a plurality of clients. The online system provides a listing for the manager's time-expiring inventory to clients on the online system. The manager specifies the price of the time-expiring inventory in the listing. A demand function predicts the demand for the time-expiring inventory based on features of the listing and the time-expiring inventory. The online system determines a likelihood of receiving a request for the time-expiring inventory from a client on the online system based on the predicted demand. The online system may use the determined likelihoods to provide to the manager information about how changes in the price of the listing are likely to affect the demand for the time-expiring inventory.

Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.

Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.

Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.

Abstract: Methods and systems for enforcing host standards in a reservation system. In one embodiment, a reservation system provides two methods of communication between a potential guest and a host, hard communications and soft communications. The reservation system associates both types of communication with threads, each thread associated with the host and an associated reservation. The reservation system determines suspension metrics for each host based on the communications of the threads they are associated with. When the suspension metrics associated with a host satisfy one or more suspension criteria, the reservation system issues a suspension to the host.

Abstract: This disclosure includes methods for predicting demand based on the price of a time-expiring inventory. An online system provides a connection between a manager of a time-expiring inventory and a plurality of clients. The online system provides a listing for the manager's time-expiring inventory to clients on the online system. The manager specifies the price of the time-expiring inventory in the listing. A demand function predicts the demand for the time-expiring inventory based on features of the listing and the time-expiring inventory. The online system determines a likelihood of receiving a request for the time-expiring inventory from a client on the online system based on the predicted demand. The online system may use the determined likelihoods to provide to the manager information about how changes in the price of the listing are likely to affect the demand for the time-expiring inventory.

Abstract: Endocardial pressure measurement devices, systems and methods for the effective treatment of congestive heart failure and its underlying causes, in addition to other clinical applications.

Abstract: The present device relates to a method of improving a indirect measurement tire pressure detection system. Such systems include a system that detects pressure loss based on wheel speed data. The present method determines reference values dependent upon driving parameters and produces a two-dimensional or multi-dimensional closed range of driving parameters. The closed range of driving parameters uses reference values that are determined to be currently valid.

Abstract: The present invention relates to a method of detecting growth of the dynamic tire circumference (circumferential growth or tire growth), wherein at least one reference value Ref is produced on the basis of wheel speed information, said reference value representing in particular a sidewise and/or crosswise relation of the motor vehicle wheels, and wherein the time variation of the reference value(s) is examined and, further, tire growth is detected on the basis of said variation.

Abstract: The present device relates to a method of improving a indirect measurement tire pressure detection system. Such systems include a system that detects pressure loss based on wheel speed data. The present method determines reference values dependent upon driving parameters and produces a two-dimensional or multi-dimensional closed range of driving parameters. The closed range of driving parameters uses reference values that are determined to be currently valid.

Abstract: A vacuum and disposal system for the collection and disposal of animal feces. The vacuum and disposal system consists of a vacuum source, a vacuum tube, a flexible hose, and an intake tube. The vacuum is provided by an electric motor powered by a rechargeable battery and is used to create a vacuum or suction through the vacuum tube, the flexible hose, and the intake tube to collect the animal feces. A cartridge having a filter is inserted into the intake tube to receive the animal feces collected. After collection, the vacuum and disposal system is converted to an unload position for the removal of the cartridge from the intake tube and the ultimate disposal of the animal feces. Alternatively, a compact vacuum and disposal system may be used in smaller areas.

Abstract: The present invention relates to a method of detecting growth of the dynamic tire circumference (circumferential growth or tire growth), wherein at least one reference value Ref is produced on the basis of wheel speed information, said reference value representing in particular a sidewise and/or crosswise relation of the motor vehicle wheels, and wherein the time variation of the reference value(s) is examined and, further, tire growth is detected on the basis of said variation.

Abstract: A vacuum and disposal system for the collection and disposal of animal feces. The vacuum and disposal system consists of a vacuum source, a vacuum tube, a flexible hose, and an intake tube. The vacuum is provided by an electric motor powered by a rechargeable battery and is used to create a vacuum or suction through the vacuum tube, the flexible hose, and the intake tube to collect the animal feces. A cartridge having a filter is inserted into the intake tube to receive the animal feces collected. After collection, the vacuum and disposal system is converted to an unload position for the removal of the cartridge from the intake tube and the ultimate disposal of the animal feces. Alternatively, a compact vacuum and disposal system may be used in smaller areas.

Abstract: Endocardial pressure measurement devices, systems and methods for the effective treatment of congestive heart failure and its underlying causes, in addition to other clinical applications.

Abstract: A reactor vessel seal for temporarily sealing a reactor pressure vessel from a water-filled refueling canal above the reactor pressure vessel. The reactor vessel seal is installed in place of the removable reactor pressure vessel closure head for inspecting/servicing the reactor vessel. The reactor seal comprises a seal cap having a surface connected to a flange which is complementary to the upper flange of the reactor pressure vessel. A seal is located between the seal cap flange and the upper flange of the reactor pressure vessel. A lifting rig is connected to the seal cap for lifting the seal cap and placing it in position, with the seal cap flange in alignment with the reactor vessel upper flange, such that the seal located between the seal cap flange and the reactor pressure vessel upper flange is compressed by hydrostatic pressure from water in the water-filled refueling canal acting on the surface of the seal cap as water in the reactor pressure vessel is evacuated.