Abstract: Disclosed are vascular occluder, kit and method of use thereof. The vascular occluder includes an occluder body extending longitudinally between an occluder body distal end and an occluder body proximal end. The occluder body is elastically compressible longitudinally from a preliminary deployed configuration to a compressed deployed configuration. Vascular occluder includes a tension member configured to tether the occluder body proximal end to the occluder body distal end and to tighten therebetween when the occluder body is in the compressed deployed configuration. The occluder body includes a proximal tubular body segment and a distal tubular body segment, and when in the compressed deployed configuration, the proximal tubular body segment is located inside of, and/or provides structural support to, the distal tubular body segment.

Abstract: The present invention relates to methods of diagnosing, monitoring, and assessing treatment effects for neurological and neurodegenerative diseases and disorders, such as Alzheimer's Disease, early in the course of clinical disease or prior to the onset of brain damage and clinical symptoms. Methods of measuring the in vivo metabolism of biomolecules produced in the CNS in a subject are provided.

Abstract: Disclosed are methods of identifying, generating and synthesizing compounds that inhibit MAPK13 activity. In various embodiments, compounds, salts thereof and prodrugs thereof of the present teachings can be useful for the treatment of diseases and disorders that involve excess mucus production.

Abstract: Enhanced configuration of security and access control for data in a storage device is disclosed. A request is received to access an addressable memory location in a storage media within the storage device. A set of addressable memory locations with contiguous addresses identified by an address range is associated with first and second characteristics. The first characteristic is applied if the addressable memory location is within the set of addressable memory locations, and an entity is currently authenticated to and authorized to access the set of addressable memory locations. The second characteristic is applied if the addressable memory location is within the set of addressable memory locations, and no entity is currently authenticated to and authorized to access the set of addressable memory locations. The set of addressable memory locations can also be a logical partition, where the first and second characteristics are stored in a logical partition table.

Abstract: Disclosed are methods of identifying, generating and synthesizing compounds that inhibit MAPK13 activity. In various embodiments, compounds, salts thereof and prodrugs thereof of the present teachings can be useful for the treatment of diseases and disorders that involve excess mucus production.

Abstract: A memory system comprises an encryption engine implemented in the hardware of a controller. In starting up the memory system, a boot strapping mechanism is implemented wherein a first portion of firmware when executed pulls in another portion of firmware to be executed. The hardware of the encryption engine is used to verify the integrity of at least the first portion of the firmware. Therefore, only the firmware that is intended to run the system will be executed.

Abstract: A method for using time from a trusted host device is disclosed. In one embodiment, an application on a memory device receives a request to perform a time-based operation from an entity authenticated by the memory device, wherein the entity is running on a host device. The application selects time from the host device instead of time from a time module on the memory device to perform the time-based operation and uses the time from the host device to perform the time-based operation. Other embodiments are disclosed, and each of the embodiments can be used alone or together in combination.

Abstract: The present invention relates to methods of diagnosing, monitoring, and assessing treatment effects for neurological and neurodegenerative diseases and disorders, such as Alzheimer's Disease, early in the course of clinical disease or prior to the onset of brain damage and clinical symptoms. Methods of measuring the in vivo metabolism of biomolecules produced in the CNS in a subject are provided.

Abstract: A mechanism or structure may be provided to divide a memory into partitions and so that at least some data in the partitions can be encrypted with a key, so that in addition to authentication that is required for accessing some of the partitions, access to one or more keys may be required to decrypt the encrypted data in such partitions. All of the content that the user wishes to access may be associated with a first account, so that all such content can be accessed via different applications (e.g. music player, email, cellular communication etc.) without having to log in multiple times. Then a different set of authentication information may then be used for logging in to access protected content that is in an account different from the first account, even where the different accounts are for the same user or entity.

Abstract: A method for improving accuracy of a time estimate from a memory device is disclosed. In one embodiment, a memory device receives a time stamp and measures active time with respect to the received time stamp. The memory device determines accuracy of previously-measured active time and generates a time estimate using the measured active time, the accuracy of previously-measured active time, and the received time stamp. In another embodiment, measured active time is adjusted, with or without generating a time estimate. Other embodiments are disclosed, and each of the embodiments can be used alone or together in combination.

Abstract: A method for improving accuracy of a time estimate used in digital rights management (DRM) license validation is disclosed. In one embodiment, a memory device receives a request to validate a DRM license stored on the memory device, wherein the DRM license is associated with a time stamp update policy (TUP) that specifies when a new time stamp is needed. Before attempting to validate the DRM license, the memory device determines if a new time stamp is needed based on the TUP associated with the DRM license. If a new time stamp is needed, the memory device receives the new time stamp and then attempts to validate the DRM license using a time estimate based on the new time stamp. Other embodiments are disclosed, and each of the embodiments can be used alone or together in combination.

Abstract: An object known as an identity object comprises a public key and a private key pair and at least one certificate issued by a certificate authority that certifies that the public key of the pair is genuine. In one embodiment, this object may be used as proof of identification by using the private key to sign data provided to it or signals derived from the data. An identity object may be stored in a non-volatile memory as proof of identity, where the memory is controlled by a controller. Preferably, a housing encloses the memory and the controller.

Abstract: A data object storing data in the memory device is associated with at least one software application. Accessing the object will invoke the at least one software application which processes the data in the object. Individual ones of a plurality of first sets of protocols are selectable for enabling data to be provided and stored in a data object. A second set of protocols can be used to retrieve data from the data object, or data derived from such data, irrespective of which of the first set of protocols was used to enable the provision and storing of data in the object.

Abstract: In some applications, it may be more convenient to the user to be able to log in the memory system using one application, and then be able to use different applications to access protected content without having to log in again. In such event, all of the content that the user wishes to access in this manner may be associated with a first account, so that all such content can be accessed via different applications (e.g. music player, email, cellular communication etc.) without having to log in multiple times. Then a different set of authentication information may then be used for logging in to access protected content that is in an account different from the first account, even where the different accounts are for the same user or entity.

Abstract: A method and memory device for implementing long operations and supporting multiple streams are provided. In one embodiment, a memory device receives data and a command from a host to perform an operation on the data, wherein a time required for the memory device to complete the operation exceeds a maximum response time for the memory device to respond to the command. The memory device begins performing the operation on the data and, before exceeding the maximum response time and before completing the operation, sends the context of the operation to the host. At a later time, the memory device receives from the host: (i) a command to resume performing the operation and (ii) the context. The memory device then resumes performing the operation on the data based on the context received from the host.

Abstract: Many storage devices are not aware of file systems while many computer host devices read and write data in the form of files. The host device provides a key reference or ID, while the memory system generates a key value in response which is associated with the key ID, which is used as the handle through which the memory retains complete and exclusive control over the generation and use of the key value for cryptographic processes, while the host retains control of files.

Abstract: A secure flash memory card or flash drive protects user content from unauthorized duplication. However, even the protected user content can be moved from one flash card or drive to another by its rightful owner or licensee. Additionally, secure firmware applications that may be added to the flash card over time in order to add additional functionality to the card may also be moved, although many of them are device specific and also designed to only operate on one particular piece of hardware.

Abstract: The throughput of the memory system is improved where error correction of data in a data stream is cryptographically processed with minimal involvement of any controller. To perform error correction when data from the memory cells are read, the bit errors in the data in the data stream passing between the cells and the cryptographic circuit are corrected prior to any cryptographic process performed by the circuit. Preferably the error correction occurs in one or more buffers employed to buffer the data between the cryptographic circuit and the memory where latency is reduced by using multiple buffers.

Abstract: A method for protection of data includes maintaining a control parameter indicative of a current version of the data. The data is partitioned into multiple segments. Respective signatures of the segments are computed, responsively to the control parameter, the segments and respective signatures forming respective signed input segments, which are stored in a memory. After the signed input segments are stored, a signed output segment is fetched from the memory. The signature of the signed output segment is verified responsively to the control parameter, and the data in the signed output segment is processed responsively to verifying the signature.

Abstract: The present invention relates to methods of diagnosing, monitoring, and assessing treatment effects for neurological and neurodegenerative diseases and disorders, such as Alzheimer's Disease, early in the course of clinical disease or prior to the onset of brain damage and clinical symptoms. Methods of measuring the in vivo metabolism of biomolecules produced in the CNS in a subject are provided.