Patents by Inventor Michael Holzmann

Michael Holzmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11180815
    Abstract: This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: November 23, 2021
    Assignee: PACIFIC EDGE LIMITED
    Inventors: Hjalmar Nekarda, Jan Friederichs, Bernhard Holzmann, Robert Rosenberg, Anthony Edmund Reeve, Michael Alan Black, John Lindsay McCall, Yu-Hsin Lin, Robert Craig Pollock
  • Patent number: 11154896
    Abstract: An aerosol generator for generating an aerosol from a fluid, comprising: a vibratable membrane having a first side for being in contact with the fluid and an opposite second side, the membrane having a plurality of through holes penetrating the membrane in an extension direction from the first side to the second side, whereby the fluid passes the through holes from the first side to the second side when the membrane is vibrated for generating the aerosol at the second side, each through hole having along its extension direction a smallest diameter, a larger diameter that is larger than the smallest diameter and defined by that diameter that is closest to triple, preferably twice said smallest diameter, each through hole having a nozzle portion defined by that continuous portion of the through hole in the extension direction comprising the smallest diameter of the through hole and bordered by the larger diameter of the through hole, wherein the ratio of the total length of each through hole in the extension di
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: October 26, 2021
    Assignee: PARI Pharma GmbH
    Inventors: Harald Schulz, Philipp Holzmann, Dominique Mutschmann, Michael Hahn
  • Patent number: 10962329
    Abstract: The invention relates to a reticle (1) for a telescopic sight (100), having a non-linear size value scale (10) and further special scales and sighting aids (30) which serve in each case for the determination of a distance to a target object or of the size thereof in order that, ultimately, a shot can be fired precisely at the target object. The invention also relates to the method for determining the distance to the target object (ZO) using the non-linear size value scale, and to telescopic sights and firearms having the reticle according to the invention.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: March 30, 2021
    Assignee: Schmidt & Bender GmbH & Co. KG
    Inventors: Jonas Höller, Michael Holzmann, Jörg Hennemann, Thomas Pehlke, Kyle Brown
  • Publication number: 20180202767
    Abstract: The invention relates to a reticle (1) for a telescopic sight (100), having a non-linear size value scale (10) and further special scales and sighting aids (30) which serve in each case for the determination of a distance to a target object or of the size thereof in order that, ultimately, a shot can be fired precisely at the target object. The invention also relates to the method for determining the distance to the target object (ZO) using the non-linear size value scale, and to telescopic sights and firearms having the reticle according to the invention.
    Type: Application
    Filed: January 12, 2018
    Publication date: July 19, 2018
    Inventors: Jonas HÖLLER, Michael HOLZMANN, Jörg HENNEMANN, Thomas PEHLKE, Kyle BROWN
  • Patent number: 5500504
    Abstract: A nozzle for a tool for the working of material and having a nozzle body which is composed of electrically conducting material and carries a nozzle electrode in its tip region with the tip region of the nozzle body and the remaining region of the nozzle body being formed by separate parts which are connected to one another and electrically insulated from one another, the nozzle electrode being in direct electrical contact with the tip region.
    Type: Grant
    Filed: November 7, 1991
    Date of Patent: March 19, 1996
    Assignee: C. A. Weidmuller GmbH & Co.
    Inventors: Manfred Jagiella, Wolf Wiesemann, Peter Schubert, Michael Holzmann, Georg Sporl
  • Patent number: 5366164
    Abstract: A nozzle for a device for machining materials, can be rigidly connected at its end opposite the nozzle tip to a connector head of the device. The connection of the nozzle with the connector head is made by a connecting element (7; 17) made of a brittle material and comprising a break-off region (11; 20). If a collision between the nozzle tip and a workpiece to be machined takes place accidentally, then the connecting element breaks in the break-off region in order to prevent further, even greater damage to the connector head, nozzle or workpiece. The break-off region is crossed by an electrical conductor (14; 27) which breaks in the event of a collision, so that in this way an alarm signal for stopping the device can be generated.
    Type: Grant
    Filed: March 10, 1992
    Date of Patent: November 22, 1994
    Assignee: Precitec GmbH
    Inventors: Manfred Jagiella, Michael Holzmann, Georg Sporl, Ahmet Topkaya
  • Patent number: 5192847
    Abstract: The invention relates to a nozzle for a tool for working material, for example for laser cutting. The nozzle contains an electrically conducting nozzle body (2), at the tip of which is arranged a nozzle electrode (12) electrically insulated from it. A cap element (15) accomodates the nozzle electrode (12) and is in engagement with the nozzle body (2). At the same time, the cap element (15) presses the nozzle electrode (12) against an insulating body (9). The cap element (15) and the nozzle electrode (12) are insulated from one another by means of an electrically non-conducting layer, making possible shielding of the nozzle electrode (12) a long way into the tip region. The cap element (15) furthermore protects the nozzle electrode (12) from lateral forces in order to avoid damage to the insulating body (9) which accommodates the nozzle electrode (12).
    Type: Grant
    Filed: September 6, 1991
    Date of Patent: March 9, 1993
    Assignee: C.A. Weidmuller GmbH & Co.
    Inventors: Manfred Jagiella, Wolf Wiesemann, Michael Holzmann