Patents by Inventor Michael Hottiger

Michael Hottiger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARTC1 LIGANDS FOR CANCER TREATMENT
    Publication number: 20230151118
    Abstract: The present invention relates to a non-agonist ligand of ARTC1, which inhibits the ADP-ribosyltransferase activity of ARTC1, or an inhibitor nucleic acid sequence capable of downregulating or inhibiting expression of a target nucleic acid sequence encoding ARTC1, for use in prevention or treatment of cancer. The invention also relates to a method for diagnosis of cancer.
    Type: Application
    Filed: April 6, 2021
    Publication date: May 18, 2023
    Applicants: UNIVERSITÄT ZÜRICH, UNIVERSITÄTSKLINIKUM HAMBURG-EPPENDORF
    Inventors: Friedrich NOLTE, Stephan MENZEL, Tobias SUTER, Michael HOTTIGER, Denise DORVIGNIT-PEDROSO, Jesus GLAUS-GARZON, Kathrin NOWAK, Fabio AIMI
  • Method and kit for detecting membrane protein-protein interactions
    Patent number: 9435055
    Abstract: The present invention is concerned with a method and a kit for detecting an interaction between a first membrane bound test protein or fragment thereof and a second test protein or fragment thereof which is either membrane bound or soluble with an in vivo genetic system based in yeast, bacterial or mammalian cells. The system makes use of the reconstitution of the split ubiquitin protein.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: September 6, 2016
    Assignee: Hybrigenics Services S.A.S.
    Inventors: Igor Stagljar, Michael Hottiger, Daniel Auerbach
  • Method and kit for detecting membrane protein-protein interactions
    Publication number: 20050106636
    Abstract: The present invention is concerned with a method and a kit for detecting an interaction between a first membrane bound test protein or fragment thereof and a second test protein or fragment thereof which is either membrane bound or soluble with an in vivo genetic system based in yeast, bacterial or mammalian cells. The system makes use of the reconstitution of the split ubiquitin protein.
    Type: Application
    Filed: March 28, 2003
    Publication date: May 19, 2005
    Inventors: Igor Stagljar, Michael Hottiger, Daniel Auerbach