Patents by Inventor Michael Hughes Smith

Michael Hughes Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liposomal Formulations for Allosteric AKT Inhibitors
    Publication number: 20190374468
    Abstract: Disclosed herein is a lipid nanoparticle (LNP) composition comprising (a) an Akt inhibitor; (b) DSPC; (c) cholesterol; and (d) PEG-DMG. Also disclosed herein is a method for preparing the lipid composition using a scalable tangential flow micro-mixing technology.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 12, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michael Hughes Smith, Marian Gindy
  • Liposomal Formulations for Allosteric AKT Inhibitors
    Publication number: 20160317444
    Abstract: Disclosed herein is a lipid nanoparticle (LNP) composition comprising (a) an Akt inhibitor; (b) DSPC; (c) cholesterol; and (d) PEG-DMG. Also disclosed herein is a method for preparing the lipid composition using a scalable tangential flow micro-mixing technology.
    Type: Application
    Filed: December 12, 2014
    Publication date: November 3, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michael Hughes Smith, Marian Gindy