Patents by Inventor Michael Hursthouse

Michael Hursthouse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of preparation of novel rhodium hydrogenation catalysts
    Patent number: 4911865
    Abstract: The present invention refers to complexes prepared by reacting rhodium trinitrate with a suitable hydrazine and a suitable tertiary phosphine, more specifically to the compounds di(.mu.-hydrazine-N.sup.1 :N.sup.2)-bis[bis(triphenylphosphine)rhodium (I)]dinitrate and .mu.-3-carbopentazane-N.sup.1, N.sup.4 :N.sup.2, N.sup.5 -bis[bis(triphenylphosphine)rhodium (I)]dinitrate, which are homogenous hydrogenation catalysts and their application in the hydrogenation of the exocyclic methylene group of acid addition salts of 6-demethyl-6-deoxy-6-methylene-5-hydroxytetracycline (methacycline) to prepare .alpha.-6-deoxy-5-hydroxy-tetracycline (doxycycline).
    Type: Grant
    Filed: March 13, 1989
    Date of Patent: March 27, 1990
    Assignee: Plurichemie Anstalt
    Inventors: William Heggie, Philip R. Page, Ivan Villax, Indira Ghatak, Michael Hursthouse
  • Application of catalysts containing rhodium
    Patent number: 4863639
    Abstract: The present invention refers to the compounds (.mu.-hydrazine-N.sup.1 :N.sup.2)-bis[bis(triphenylphosphine)-chlororhodium (I)] and di(.mu.-hydrazine-N.sup.1 :N.sup.2)-bis[bis(triphenylphosphine)rhodium (I)] dichloride, which are homogenous hydrogenation catalysts and their application in the hydrogenation of the exocyclic methylene group of acid addition salts of 6-demethyl-6-deoxy-6-methylene-5-hydroxytetracycline (methacycline) to prepare .alpha.-6-deoxy-5-hydroxytetracycline (doxycycline).
    Type: Grant
    Filed: May 15, 1987
    Date of Patent: September 5, 1989
    Assignee: Plurichemie Anstalt
    Inventors: William Heggie, Philip R. Page, Ivan Villax, Michael Hursthouse, Richard Somerville
  • Process of preparation of novel rhodium hydrogenation catalysts and their application
    Patent number: 4857235
    Abstract: The present invention refers to complexes prepared by reacting rhodium trinitrate with a suitable hydrazine and a suitable tertiary phosphine, more specifically to the compounds di(.mu.-hydrazine-N.sup.1 :N.sup.2)-bis[bis(triphenylphosphine)rhodium (I)]dinitrate and .mu.-3-carbopentazane-N.sup.1,N.sup.4 :N.sup.2,N.sup.5 -bis[bis(triphenylphosphine)rhodium (I)]dinitrate, which are homogeneous hydrogenation catalysts and their application in the hydrogenation of the exocyclic methylene group of acid addition salts of 6-demethyl-6-deoxy-6-methylene-5-hydroxytetracycline (methacycline) to prepare .alpha.-6-deoxy-5-hydroxy-tetracycline (doxycycline).
    Type: Grant
    Filed: May 15, 1987
    Date of Patent: August 15, 1989
    Assignee: Plurichemie Anstalt
    Inventors: William Heggie, Philip R. Page, Ivan Villax, Indira Ghatak, Michael Hursthouse