Abstract: The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.

Abstract: One example includes a MOT system. The system includes first optical source configured to provide a plurality of first optical beams parallel to a central axis associated with the MOT system, and a first set of optics configured to focus the first optical beams to the central axis through a trapping region comprising a vapor of atoms. The system also includes a second optical source configured to provide a plurality of second optical beams parallel to the central axis associated with the MOT system, and a second set of optics configured to focus the second optical beams to the central axis through the trapping region. Each of the second optical beams can be coaxial with a respective one of the first optical beams, such that each of the first optical beams is counterpropagating with a respective one of the second optical beams.

Abstract: Systems and methods for managing multi-objective alignments in imprinting (e.g., single-sided or double-sided) are provided. An example system includes rollers for moving a template roll, a stage for holding a substrate, a dispenser for dispensing resist on the substrate, a light source for curing the resist to form an imprint on the substrate when a template of the template roll is pressed into the resist on the substrate, a first inspection system for registering a fiducial mark of the template to determine a template offset, a second inspection system for registering the imprint on the substrate to determine a wafer registration offset between a target location and an actual location of the imprint, and a controller for controlling to move the substrate with the resist below the template based on the template offset, and determine an overlay bias of the imprint on the substrate based on the wafer registration offset.

Abstract: A camshaft (24), in particular for a pump (10), is proposed. The camshaft (24) has at least two cams (26, 28) which are arranged next to one another in the direction of the longitudinal axis (25) of the camshaft (24) and the cam elevations of which are arranged offset with respect to one another around the longitudinal axis (25) of the camshaft (24). An intermediate region (30) is provided between two adjacent cams (26, 28), and at least one bearing region (32) is arranged next to the cams (26, 28) in the direction of the longitudinal axis (25) of the camshaft (24).

Abstract: A camshaft (24), in particular for a pump (10), is proposed. The camshaft (24) has at least two cams (26, 28) which are arranged next to one another in the direction of the longitudinal axis (25) of the camshaft (24) and the cam elevations of which are arranged offset with respect to one another around the longitudinal axis (25) of the camshaft (24). An intermediate region (30) is provided between two adjacent cams (26, 28), and at least one bearing region (32) is arranged next to the cams (26, 28) in the direction of the longitudinal axis (25) of the camshaft (24).

Abstract: A method for detecting failures in electrical cable assemblies is provided. A cable test instrument obtains frequency domain data representing electrical characteristics of a cable link under test. A number of connectors in the cable link under test is determined based on the obtained frequency domain data. An estimated location of each of the connectors along the length of the cable link under test is determined by the cable test instrument. The connectors are ranked in accordance with their respective contribution to detected failures in the cable link under test.

Abstract: A two-component mold assembly for molding an opening within a concrete wall that provides access to a piping system supporting a sprinkler. The first component is an insert that is mounted on a concrete form, and the second component is a cover that slidably fits over the insert to define the opening in the concrete. The cover plugs the piping system during fabrication of the concrete wall and is removable from the opening in the hardened concrete after the concrete form and the mounted insert are removed.

Abstract: A method for detecting failures in electrical cable assemblies is provided. A cable test instrument obtains frequency domain data representing electrical characteristics of a cable link under test. A number of connectors in the cable link under test is determined based on the obtained frequency domain data. An estimated location of each of the connectors along the length of the cable link under test is determined by the cable test instrument. The connectors are ranked in accordance with their respective contribution to detected failures in the cable link under test.

Abstract: A hand held test instrument for testing a DSL line is provided. The test instrument includes an interface for unintrusive connection with the DSL under test. The interface is configured to capture Radio Frequency (RF) signals corresponding to a portion of a data stream transmitted by a communication device over the DSL under test. The hand held test instrument further includes a controller module configured to identify unique characteristics of the communication device based on the captured RF signals.

Abstract: Imprint lithography templates having alignment marks with highly absorptive material. The alignment marks are insensitive to the effects of liquid spreading and can provide stability and increase contrast to alignment system during liquid imprint filling of template features.

Abstract: Imprint lithography templates having alignment marks with highly absorptive material. The alignment marks are insensitive to the effects of liquid spreading and can provide stability and increase contrast to alignment system during liquid imprint filling of template features.

Abstract: Two-stage imprinting techniques capable of protecting fine patterned features of an imprint lithography template are herein described. In particular, such techniques may be used during fabrication of recessed high-contrast alignment marks for preventing deposited metal layers from coming into contact with fine features etched into the template.

Abstract: A two-component mold assembly for molding an opening within a concrete wall that provides access to a piping system supporting a sprinkler The first component is an insert that is mounted on a concrete form, and the second component is a cover that slidably fits over the insert to define the opening in the concrete. The cover plugs the piping system during fabrication of the concrete wall and is removeable from the opening in the hardened concrete after the concrete form and the mounted insert are removed.

Abstract: Imprint lithography templates having alignment marks with highly absorptive material. The alignment marks are insensitive to the effects of liquid spreading and can provide stability and increase contrast to alignment system during liquid imprint filling of template features.

Abstract: Two-stage imprinting techniques capable of protecting fine patterned features of an imprint lithography template are herein described. In particular, such techniques may be used during fabrication of recessed high-contrast alignment marks for preventing deposited metal layers from coming into contact with fine features etched into the template.