Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; a delivery passageway (34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 ?m=<10%.

Abstract: The present invention provides a dry powder inhaler comprising: a reservoir containing a dry powder formulation and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator for breaking up agglomerates of the dry powder medicament; and a delivery passageway for directing an inhalation-induced air flow through a mouthpiece, the delivery passageway extending to the metered dose of medicament, wherein the formulation comprises an inhalable ?2-agonist having a particle size distribution of d1O<1 ???=1-3 ???, d90=3.5-6 ?m and NLT 99% 10 ?m and a lactose carrier.

Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; a delivery passageway (34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 ?m=<10%.

Abstract: Described herein is a dry powder inhaler which includes: a reservoir containing a dry powder formulation and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator for breaking up agglomerates of the dry powder medicament; a delivery passageway for directing an inhalation-induced air flow through a mouthpiece, the delivery passageway extending to the metered dose of medicament, and an inhalable ?2-agonist having a particle size distribution of d10<1 ?m, d50=1-3 ?m, d90=3.5-6 ?m and NLT 99% 10 ?m and a lactose carrier.

Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; a delivery passageway (34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 um=<10%.

Abstract: This invention provides a budesonide/formoterol dry powder inhaler (10) comprising: •a reservoir (14) containing a dry powder medicament and an arrangement for delivering a metered dose of the medicament from the reservoir; •a cyclone deagglomerator (10?) for breaking up agglomerates of the dry powder medicament; •a delivery passageway/34) for directing an inhalation-induced air flow through a mouthpiece (24), the delivery passageway extending to the metered dose of medicament, •wherein the medicament comprises micronised formoterol fumarate, micronised budesonide and a lactose carrier, the lactose carrier having a particle size distribution of d10=20-65 ?m, d50=80-120 ?m, d90=130-180 ?m and <10 um=<10%.

Abstract: The present invention provides a dry powder inhaler comprising: a reservoir containing a dry powder formulation and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator for breaking up agglomerates of the dry powder medicament; and a delivery passageway for directing an inhalation-induced air flow through a mouthpiece, the delivery passageway extending to the metered dose of medicament, wherein the formulation comprises an inhalable ?2-agonist having a particle size distribution of d10<1 ?m, d50=1-3 ?m, d90=3.5-6 ?m and NLT 99% 10 ?m and a lactose carrier.