Patents by Inventor Michael Inbar

Michael Inbar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5314074
    Abstract: In the performance of density gradient centrifugation back mixing after centrifugation is prevented by placing a snugly fitted layering insert within the vessel. The insert is capable of supporting the body of liquid dispersion to be centrifuged under regular gravity condition and enables bi-directional cross-flow during centrifugation. A small mesh filter plate may be placed on top of the layering insert.
    Type: Grant
    Filed: November 3, 1992
    Date of Patent: May 24, 1994
    Assignee: Eldan Technologies Co. Ltd.
    Inventors: Michael Inbar, Gerald Slutzky, Mordechai Radushetzky, David Shitrit
  • Patent number: 5150337
    Abstract: An apparatus and a method for determining the time difference between electrical events utilizes a sinusoidal signal as a reference from which to determine the elapsed time between events represented as electrical pulses. A sine wave and a cosine wave are multiplexed to produce the sinusoidal reference signal. When an event occurs, as indicated by an electrical pulse, the sine wave and the cosine wave are sampled to produce two digital values. A comparator determines which of the two digital values falls within a predetermined range, and transmits a select signal to multiplexer. The multiplexer selects the digital value which falls within the predetermined range. The selected digital value corresponds to an angle value which can be uniquely determined within one cycle of the sinusoidal reference signal. A cycle counter accounts for the number of full cycles which elapse until the next event is detected.
    Type: Grant
    Filed: February 21, 1990
    Date of Patent: September 22, 1992
    Assignee: Applied Magnetics Corporation
    Inventor: Michael Inbar
  • Patent number: 4883765
    Abstract: A method, device and kit for the quantitative determination of lipoprotein components, especially cholesterol and triglycerides, in body fluids, especially human serum, plasma or whole blood utilizing the selective adsorption of lipoproteins on particulate silica. This selective adsorption is also useful for the quantitative separation of lipoproteins from samples of whole blood for diagnostic purposes.
    Type: Grant
    Filed: August 28, 1987
    Date of Patent: November 28, 1989
    Assignee: I.D.L. Int'l Diagnostic Laboratories Ltd.
    Inventors: Ilana Tamir, Ben-Zion Kidron, Lynn Wang, Michael Inbar
  • Patent number: 4727023
    Abstract: A reagent for use in solid phase immunoassay diagnostics comprises a matrix of non-active hybridoma cells embedded with its self-produced, covalently bound, actively presented monoclonal antibodies.The solid phase reagent according to the invention is prepared by incubating in vitro a culture medium containing active hybridoma cells capable of producing monoclonal antibodies, allowing the formation of antibodies to proceed, separating and washing said cells, resuspending the cells in a buffer solution, adding to the resulting suspension an inactivator substance capable of converting active hybridoma cells into the non-active state.
    Type: Grant
    Filed: September 9, 1985
    Date of Patent: February 23, 1988
    Assignee: I.D.L. International Diagnostic Laboratories Limited
    Inventors: Lynn Wang, Michael Inbar
  • Patent number: 4651102
    Abstract: A method of converting a pulse train of electrical signals having a frequency within a known frequency range into digital signals is shown.
    Type: Grant
    Filed: November 1, 1985
    Date of Patent: March 17, 1987
    Assignee: Applied Magnetics Corp.
    Inventor: Michael Inbar
  • Patent number: 4651105
    Abstract: A digital peak detecting circuit for receiving a pulse train of electrical signals having a frequency within a known frequency range and for converting the same into digital signals is shown. The digital peak detecting circuit includes an input circuit having a phase-locked loop for producing clock pulses at a frequency which is a preselected integer of the electrical signals frequency and for deriving therefrom an analog input signal. A pulse control circuit receives and counts a predetermined number of clock pulses and produces count enabling signals. A peak detecting circuit is provided which includes a comparator which has the analog input signal and a analog output signal voltage applied to the inputs thereof and which has an output coupled to the pulse control circuit.
    Type: Grant
    Filed: November 1, 1985
    Date of Patent: March 17, 1987
    Assignee: Applied Magnetics Corp.
    Inventor: Michael Inbar
  • Patent number: 4574234
    Abstract: An electrical measuring system for measuring selected parameters of electrical signals derived from magnetic recording and having a frequency within a known frequency range wherein the system includes an input stage having an automatic amplifier for selectively amplifying the electrical signals to a preselected amplitude level, a first circuit which includes a digital peak detecting circuit for producing digital signals representing peak amplitude and the amplitude of the electrical signals sampled at closely spaced intervals and wherein the digital peak detecting circuit includes circuitry for sampling the preselected amplitude level electrical signals at a frequency which is less than the frequency of the electrical signals, a second circuit which includes a first phase-locked loop circuit, a frequency dividing circuit and a second phase-locked loop circuit for producing an output signal representing the frequency of a remnant signal in the electrical signals which is applied to the digital peak detecting c
    Type: Grant
    Filed: September 26, 1984
    Date of Patent: March 4, 1986
    Assignee: Applied Magnetics Corporation
    Inventor: Michael Inbar
  • Patent number: 4239332
    Abstract: This invention provides for a relay apparatus for use with optical fibers. A first set of optical fiber ends is mechanically secured in a suitably shaped retainer. A second set of optical fiber ends is secured in a second retainer appropriately shaped to move into one of a plurality of mechanically stable positions with respect to the first retainer when biased against the first retainer. These mechanically stable positions bring members of the first and second set of optical fibers into optical alignment. A switching mechanism is provided for moving the first retainer across the second retainer thereby making and breaking optical connections between the first and second set of optical fiber ends. In one embodiment, the retainers are cooperatively shaped by hemispheres, which define a set of mechanically stable alignment positions.
    Type: Grant
    Filed: April 13, 1979
    Date of Patent: December 16, 1980
    Assignee: TRW Inc.
    Inventor: Michael Inbar
  • Patent number: 4131800
    Abstract: The normality of a cell labelled with a lipid soluble fluorescent dye and excited with a beam of polarized light can be evaluated by measuring the time dependence of the state of polarization of fluorescence emitted by the cell which is determined by simultaneously measuring the intensities of fluorescence polarized in directions parallel and perpendicular to the direction of polarization of the excitation beam.The state of polarization of a cell changes markedly as a function of excitation time when the cell is abnormal (i.e., malignant), while the state of polarization of a cell remains substantially constant when the cell is normal. Classification of cells in a population by way of the stability of the state of polarization provides guidance in determining the presence of malignancy in the population.
    Type: Grant
    Filed: March 3, 1977
    Date of Patent: December 26, 1978
    Assignee: Elscint Ltd.
    Inventors: Avraham Bruck, Michael Inbar
  • Patent number: 3971952
    Abstract: Abnormal behavior of mammalian cells is detected in vitro by measuring the fluidity or an associated phenomenon of the lipid layer of the cell surface membrane. Abnormal behavior of cells, in particular if caused by malignant transformations, is associated with increase of fluidity of the liquid layer of the cell membrane, as compared with normal cells. The fluidity can be determined, e.g., by measuring the degree of fluorescence polarization of the radiation emitted from a suspension of cells labelled in the lipid layer with a fluorescent compound. 1,6-Diphenyl-1,3,5-hexatriene was found to be a suitable fluorescent probe.
    Type: Grant
    Filed: September 12, 1974
    Date of Patent: July 27, 1976
    Assignee: Yeda Research & Development Co. Ltd.
    Inventors: Michael Inbar, Meir Shinitzky