Patents by Inventor Michael J. Bosse

Michael J. Bosse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140274881
    Abstract: Compositions that include antimicrobial agents and biodegradable delivery vehicles adapted to enter a cell and release the antimicrobial agents in the cell as they biodegrades. Also provided are compositions that include first and second delivery vehicles including first and second antimicrobial agents, wherein the first delivery vehicles are adapted to release the first antimicrobial agents at a rate that differs from that at which the second delivery vehicles release the second antimicrobial agents, articles of manufacture that include one or more biodegradable delivery vehicles, and methods of making and using the compositions to treat intracellular and/or extracellular infections are disclosed.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Applicants: CAROLINAS HEALTHCARE SYSTEM, THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE
    Inventors: Kenneth E. Gonsalves, Michael J. Bosse, John Kent Ellington, Michael Hudson, James Horton
  • Publication number: 20110218140
    Abstract: Compositions that include antimicrobial agents and biodegradable delivery-vehicles adapted to enter a cell and release the antimicrobial agents in the cell as they biodegrade. Also provided are compositions that include first and second delivery vehicles including first and second antimicrobial agents, wherein the first delivery vehicles are adapted to release the first antimicrobial agents at a rate that differs from that at which the second delivery vehicles release the second antimicrobial agents, articles of manufacture that include one or more biodegradable delivery vehicles, and methods of making and using the compositions to treat intracellular and/or extracellular infections are disclosed.
    Type: Application
    Filed: January 13, 2009
    Publication date: September 8, 2011
    Inventors: Kenneth E. Gonsalves, Michael J. Bosse, John Kent Ellington, Michael C. Hudson, James M. Horton
  • Patent number: 6140285
    Abstract: A composition for cleaning petroleum contaminated surfaces includes 5 to 60 percent by weight of a dioctyl sulfosuccinate salt, 20 to 50 percent by weight of a carrier composition and 10 to 75 percent by weight of a diluent. The preferred carrier composition is a mixture of polyethylene glycol and glycerol. The preferred diluent is water. The preferred concentration of sodium dioctyl sulfosuccinate is about 7% by weight. The preferred dioctyl sulfosuccinate salt is sodium dioctyl sulfosuccinate. A method of cleaning petroleum contaminated surfaces is also provided. The steps include providing a solution containing dioctyl sulfosuccinate salt, a carrier composition, and a diluent as described above and treating the petroleum contaminated surface with the solution in a manner and for a time sufficient to decontaminate the surface. The preferred method of treatment comprises contacting the solution with the petroleum contaminated surface for a time sufficient to create an emulsion and then removing the emulsion.
    Type: Grant
    Filed: March 13, 2000
    Date of Patent: October 31, 2000
    Assignee: Charlotte-Mecklenburg Hospital Authority
    Inventors: David M. Banks, Michael J. Bosse, Martha H. Meyer, Ralph A. Meyer, Jr., Laura S. Phieffer, Kevin L. Smith