Patents by Inventor Michael J. Bower

Michael J. Bower has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of proteins that bind phosphorylated molecules
    Patent number: 7141596
    Abstract: The present invention provides compounds that can modulate the activity of a target protein, such as a phosphatase, that selectively binds phosphorylated peptides or proteins. The present compounds can be useful in treating diseases or disorders, including, for example, diabetes and obesity, that are connected directly or indirectly to the activity of the target protein.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: November 28, 2006
    Assignee: Incyte Corporation
    Inventors: Andrew P. Combs, Eddy Wai Tsun Yue, Michael J. Bower, Wenyu Zhu, Matthew L. Crawley, Richard B. Sparks, James R. Pruitt, Amy Takvorian
  • 3,4-Dihydro-(1H) quinazolin-2-one compounds as CSBP/P38 kinase inhibitors
    Patent number: 7053098
    Abstract: Novel substituted quinazoline compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: May 30, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Michael J. Bower, Jeffrey C. Boehm, Don Edgar Griswold, David C. Underwood
  • 3,4-dihydro-(1H)quinazolin-2-one compounds as CSBP/p38 kinase inhibitors
    Patent number: 7053099
    Abstract: Novel substituted quinazoline compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: May 30, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Michael J. Bower, Ralph Hall, Don Edgar Griswold, David C. Underwood
  • 3,4-dihydro-(1H)quinazolin-2-one compounds as CSBP/p38 kinase inhibitors
    Patent number: 6982270
    Abstract: Substituted quinazolinone compounds of formula (I) and compositions thereof for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: January 3, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Michael J. Bower, Jeffrey C. Boehm, Don Edgar Griswold, David C. Underwood
  • 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
    Patent number: 6759410
    Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolines of formula (1), or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: July 6, 2004
    Assignee: SmithLine Beecham Corporation
    Inventors: Jerry L. Adams, Michael J. Bower, Ralph Hall, Don Edgar Griswold, David C. Underwood