Abstract: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.

Abstract: In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.

Abstract: In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.

Abstract: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.

Abstract: An imaging pixel array and associated method and system are disclosed in which the array contains first pixels each having a first photo-conversion device, and second pixels each having a first photo-conversion device and a second photo-conversion device. The first photo-conversion devices are configured to acquire an image during a first integration period. The second photo-conversion devices are configured to acquire a plurality of images during the first integration period. A circuit uses the plurality of image signals and determines from them relative motion between the array and an image during a portion of the first integration period and provides a signal representing the motion which is used for image stabilization.

Abstract: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.

Abstract: In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.

Abstract: A peripheral apparatus includes a housing, a semiconductor device, and an antenna. The peripheral apparatus generates and transmits radio frequency (RF) control signals to a host device. The semiconductor device is contained within the housing and generates the RF control signals. The antenna is fully contained within the semiconductor device and transmits the RF control signals to the host device.

Abstract: A contaminant-neutralizing cradle comprises a base and a support surface configured to removably receive a coherently-illuminated mouse. A neutralizing element is disposed on the support surface for alignment with at least one exposed surface of an optics module of the mouse and is configured to neutralize the optical effect of a contaminant on the at least one exposed surface. A method of neutralizing contaminants for an optical mouse comprises providing a mouse containing an optics module having at least one surface exposed to an opening of the mouse and interposing a barrier in the mouse between a contaminant and the at least one exposed surface.

Abstract: An integrated circuit package includes an angled one-piece substrate having a light source fixed to one area and a sensor die fixed to a second area, such that the light source is directed to illuminate the field of view of the sensor die when a surface of interest is imaged. The integrated circuit package is well suited for generating navigation information regarding movement relative to a surface. In one method of forming the integrated circuit package, the single-piece substrate is originally a generally flat lead frame to which the sensor die and light source are attached. After the components have been connected, the lead frame is bent to provide the desired light source-to-sensor angle. In an alternative method, the lead frame is pre-bent. For either method, optics may be connected to the integrated circuit package, thereby providing a module that includes the optics, the light source, the sensor and the packaging body.

Abstract: A device includes a light emitter, a current sensing resistance, a current generator, and detection circuitry. The current generator is connected to the light emitter and to the current sensing resistance. During a normal operating mode of the device, the current generator regulates current flow through the light emitter. In a test mode, the current generator regulates current flow through the current sensing resistance. The detection circuitry, during the test mode, detects when current flow through the current sensing resistance is outside an expected range.

Abstract: An apparatus for controlling the position of a screen pointer includes an at least partially coherent light source for illuminating an imaging surface, thereby generating reflected images. The apparatus includes a navigation sensor for generating digital images based on the reflected images, performing a movement computation based on the digital images, generating movement data based on the movement computation that is indicative of relative motion between the imaging surface and the apparatus, wherein the movement computation has a low sensitivity to effects in the digital images caused by particle contamination.

Abstract: An apparatus for controlling the position of a screen pointer includes an at least partially coherent light source for illuminating an imaging surface, thereby generating reflected images. The apparatus includes a navigation sensor for generating digital images based on the reflected images, performing a movement computation based on the digital images, generating movement data based on the movement computation that is indicative of relative motion between the imaging surface and the apparatus, wherein the movement computation has a low sensitivity to effects in the digital images caused by particle contamination.

Abstract: A contaminant-neutralizing cradle comprises a base and a support surface configured to removably receive a coherently-illuminated mouse. A neutralizing element is disposed on the support surface for alignment with at least one exposed surface of an optics module of the mouse and is configured to neutralize the optical effect of a contaminant on the at least one exposed surface. A method of neutralizing contaminants for an optical mouse comprises providing a mouse containing an optics module having at least one surface exposed to an opening of the mouse and interposing a barrier in the mouse between a contaminant and the at least one exposed surface.

Abstract: A pointing device includes a moveable puck, a first surface on which a puck field of motion is defined, and a controller. The total distance the puck can move from its centered or resting position is divided into N regions using one or more transition points. Each transition point corresponds to a puck position at which the cursor speed changes. The controller determines the position of the puck within the puck field of motion and, based on the current puck position and at least one transition point, the controller determines a speed at which the cursor is to be moved.

Abstract: Optical motion sensing systems and methods are described. In one aspect, light from subfields of a scene is focused onto respective capture areas of a focal plane. Successive sets of contemporaneous local images are captured from the focused light. Respective saliency measures are derived from respective ones of the local images. Respective local motion measures are determined from comparisons of corresponding ones of the local images in ones of the contemporaneous local image sets. A respective global motion measure is produced for each of the contemporaneous local image sets based on the respective ones of the local motion measures and the respective ones of the saliency measures.

Abstract: An apparatus for controlling the position of a screen pointer for an electronic device having a display screen, includes a light source for illuminating an imaging surface with a plurality of light pulses, thereby generating reflected light pulses. A detection circuit is configured to sense light, distinguish between the reflected pulses and ambient light, and generate a low signal indication if the magnitude of the reflected pulses falls below a threshold value. An optical motion sensor generates digital images based on the reflected pulses. The motion sensor is configured to generate movement data based on the digital images. The movement data is indicative of relative motion between the imaging surface and the apparatus.

Abstract: An apparatus for controlling the position of a screen pointer includes a movement sensor for sensing relative movement between the apparatus and a surface, and generating corresponding movement data. The movement sensor is configured to generate compressed data representing the movement data. The apparatus includes a wireless transmitter for wirelessly transmitting the compressed data.

Abstract: A device includes a light emitter, a current sensing resistance, a current generator, and detection circuitry. The current generator is connected to the light emitter and to the current sensing resistance. During a normal operating mode of the device, the current generator regulates current flow through the light emitter. In a test mode, the current generator regulates current flow through the current sensing resistance. The detection circuitry, during the test mode, detects when current flow through the current sensing resistance is outside an expected range.

Abstract: An integrated circuit package includes an angled one-piece substrate having a light source fixed to one area and a sensor die fixed to a second area, such that the light source is directed to illuminate the field of view of the sensor die when a surface of interest is imaged. The integrated circuit package is well suited for generating navigation information regarding movement relative to a surface. In one method of forming the integrated circuit package, the single-piece substrate is originally a generally flat lead frame to which the sensor die and light source are attached. After the components have been connected, the lead frame is bent to provide the desired light source-to-sensor angle. In an alternative method, the lead frame is pre-bent. For either method, optics may be connected to the integrated circuit package, thereby providing a module that includes the optics, the light source, the sensor and the packaging body.