Abstract: A handheld ophthalmic device configured to perform various optical diagnostic tests to determine the health of a subject's eye. The handheld ophthalmic device is configured to be attached to a smartphone, a cell phone or an electronic tablet. The smartphone, a cell phone or an electronic tablet can be used to view images obtained by the handheld ophthalmic device and to transmit data and images obtained by the handheld ophthalmic device to an ophthalmologist located remotely.

Abstract: This disclosure provides peptides which can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer; treating infectious diseases; enhancing a response to vaccination; treating sepsis; and promoting hair re-pigmentation or lightening of pigmented skin lesions.

Abstract: A computing system receives sensor data that includes, for a reporting aeronautical vehicle of a set of one or more reporting aeronautical vehicles, one or more images captured by the reporting aeronautical vehicle. For the image of the sensor data, the computing system identifies one or more candidate landing zones within the image. For the candidate landing zone identified, the computing system estimates a geographic position of the candidate landing zone; and associates an identifier of the candidate landing zone with the geographic position. The computing system receives, from a client device, a request for a landing zone for an aeronautical vehicle. Responsive to the request, the computing system selects from among the one or more candidate landing zones, a target candidate landing zone; and sends the geographic position estimated for the target candidate landing zone to the client device.

Abstract: A computer-implemented method includes: receiving, by a computing device, input data for identifying one or more landing site candidates for an aerial vehicle. The input data includes a set of criteria, terrain information, and obstacle information. The method further includes identifying, by the computing device, the one or more landing site candidates based on the input data and the criteria; providing, by the computing device, information regarding the identified one or more landing site candidates.

Abstract: The present disclosure generates a digital twin of the interior of a vehicle to initiate and track maintenance issues. In one aspect, the digital twin is formed using multiple captured images of the interior of the vehicle where multiple components in those images are identified using a machine learning (ML) model. The components identified by the ML model are then mapped to a model (e.g., a 3D model) of the components that lists their location in the vehicle and an identifier (e.g., a part number or serial number). In this manner, the digital twin can identify, using the identifiers, the various components in the images captured by a camera.

Abstract: A system for consumer goods management includes at least one sensor and at least one processor. The at least one sensor is configured to identify consumables and provide tracking information corresponding to the consumables. The at least one processor configured to acquire consumption information for a trip to be performed; determine a meal plan based on the consumption information, the meal plan specifying a plurality of types of consumables, quantities of the types of consumables, and a storage arrangement of the types of consumables; and acquire the tracking information from the at least one sensor to implement the meal plan.

Abstract: A computer-implemented method includes: receiving, by a computing device, input data for identifying one or more landing site candidates for an aerial vehicle. The input data includes a set of criteria, terrain information, and obstacle information. The method further includes identifying, by the computing device, the one or more landing site candidates based on the input data and the criteria; providing, by the computing device, information regarding the identified one or more landing site candidates.

Abstract: A system for consumer goods management includes at least one sensor and at least one processor. The at least one sensor is configured to identify consumables and provide tracking information corresponding to the consumables. The at least one processor configured to acquire consumption information for a trip to be performed; determine a meal plan based on the consumption information, the meal plan specifying a plurality of types of consumables, quantities of the types of consumables, and a storage arrangement of the types of consumables; and acquire the tracking information from the at least one sensor to implement the meal plan.

Abstract: Methods are disclosed for assessing the toxic or pathologic effects of a selected environmental stimulus or reagent on a mammalian cell by determining on a DNA grid a “fingerprint” hybridization pattern. The fingerprint pattern is characteristic of chemically or structurally diverse stimuli or reagents, which having a common adverse effect on gene transcription. A test compound is screened for a similar toxic effect by comparing its hybridization pattern on a similar grid to the fingerprint.

Abstract: A hybrid plasminogen activator which comprises the five kringle domains of plasminogen linked to the B-chain of t-PA or u-PA via an amino acid sequence comprising, respectively, the t-PA cleavage site between residues 275 and 276 and the cysteine residue 264 of t-PA or the u-PA cleavage site between residues 158 and 159 and the cysteine residue 148 of u-PA, or a derivative of a plasminogen activator comprising the serine protease domain of t-PA or u-PA, in which the catalytic site essential for plasminogen activator activity is blocked by a 2-aminobenzoyl group substituted in the 3- or 4-position with a halogen atom and optionally further substituted with one or more weakly electron-withdrawing or electon-donating groups, wherein the pseudo first order rate constant for hydrolysis of the derivative is in the range 6.0.times.10.sup.-5 to 4.0.times.10.sup.-4 sec.sup.-1 when measured in a buffer system consisting of 0.05M sodium phosphate, 0.1M sodium chloride, 0.