Abstract: A nuclear magnetic resonance (NMR) sample tube is made of a polymeric material instead of glass. Such tubes are thinner than glass tubes, thus increasing the internal volume and sample size. Such tubes are also more closely matched to the magnetic susceptibility of specific solvents. Such tubes have greater mechanical stability, thus leading to less tube breakage during NMR processing. Such tubes also lend themselves to various concentric tubal arrangements which permit separation and mixing of samples to minimize subtraction artifacts in interacting systems.