Patents by Inventor Michael J. Clare-Salzler

Michael J. Clare-Salzler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen-specific, tolerance-inducing microparticles and uses thereof
    Patent number: 10987314
    Abstract: The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.
    Type: Grant
    Filed: July 1, 2018
    Date of Patent: April 27, 2021
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Benjamin George Keselowsky, Jamal Lewis, Abhinav Acharya, Michael J. Clare-Salzler
  • ANTIGEN-SPECIFIC, TOLERANCE-INDUCING MICROPARTICLES AND USES THEREOF
    Publication number: 20180303760
    Abstract: The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.
    Type: Application
    Filed: July 1, 2018
    Publication date: October 25, 2018
    Inventors: BENJAMIN GEORGE KESELOWSKY, JAMAL LEWIS, ABHINAV ACHARYA, MICHAEL J. CLARE-SALZLER
  • Antigen-specific, tolerance-inducing microparticles and uses thereof
    Patent number: 10016371
    Abstract: The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.
    Type: Grant
    Filed: October 24, 2011
    Date of Patent: July 10, 2018
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION
    Inventors: Benjamin George Keselowsky, Jamal Lewis, Abhinav Acharya, Michael J. Clare-Salzler
  • ANTIGEN-SPECIFIC, TOLERANCE-INDUCING MICROPARTICLES AND USES THEREOF
    Publication number: 20130287729
    Abstract: The present invention provides antigen-specific, tolerance-inducing microparticles for the targeted delivery of therapeutic agents to immune cells. In addition, the present invention allows for sustained release of therapeutic agents for a prolonged period of time. Also provided are therapeutic uses of the present invention for the prevention and/or treatment of immune diseases and autoimmune disorders. In a specific embodiment, the present invention provides treatment for type 1 diabetes.
    Type: Application
    Filed: October 24, 2011
    Publication date: October 31, 2013
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Benjamin George Keselowsky, Jamal` Lewis, Abhinav Acharya, Michael J. Clare-Salzler, Mark A. Atkinson, Clive Henry Wasserfall, Chang Qing Xia, Todd M. Brusko
  • Materials and Methods for the Detection, Prevention and Treatment of Autoimmune Disease
    Publication number: 20100178652
    Abstract: The subject invention provides materials and methods for the detection, prevention, and treatment of diabetes and other autoimmune conditions.
    Type: Application
    Filed: January 7, 2008
    Publication date: July 15, 2010
    Inventors: Sally A. Litherland, Marcia McDuffie, Laurence Morel, Federica Seydel, Erin Garrigan, Nicole S. Belkin, Bryan Stutevoss, Michael J. Clare-Salzler, Mark A. Atkinson, Clive Henry Wasserfall, Ammon B. Peck, Abdolreza Davoodi-Semiromi
  • COX-2 mediated altered prostaglandin balance in diabetes complications
    Publication number: 20040121489
    Abstract: The subject invention concerns novel methods for determining an individual's risk of developing diabetes-related complications. An embodiment provides determining at the onset or prior to the onset of Type I diabetes those individuals with a high risk of developing diabetes-related complications. The subject invention also concerns therapeutic methods for inhibiting and/or preventing the development of diabetes-related complications prior to or at the onset of T1D.
    Type: Application
    Filed: August 29, 2003
    Publication date: June 24, 2004
    Inventors: Vikas R. Dharnidharka, Michael J. Clare-Salzler
  • Peptides derived from glutamic acid decarboxylase
    Patent number: 5674978
    Abstract: Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: October 7, 1997
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman, Michael J. Clare-Salzler
  • Cloned glutamic acid decarboxylase peptides
    Patent number: 5475086
    Abstract: Isolated polypeptides useful in ameliorating autoimmune disease.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: December 12, 1995
    Assignee: The Regents of the University of California
    Inventors: Allan J. Tobin, Mark G. Erlander, Daniel L. Kaufman, Michael J. Clare-Salzler