Patents by Inventor Michael J. Coggiola

Michael J. Coggiola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for the detection and identification of trace organic substances from a continuous flow sample system using laser photoionization-mass spectrometry
    Patent number: 7161145
    Abstract: A method and apparatus are provided for identifying analytes at low concentrations in a liquid sample. The liquid sample is introduced through a continuous flow membrane inlet system. The analytes that permeate the membrane are analyzed by photoionization-time-of-flight mass spectrometry. The analytes remaining in the liquid sample that do not permeate the membrane are conducted to a capillary tube inlet that introduces the liquid sample and other analytes as droplets into the photoionization zone. Any analytes remaining absorbed or adsorbed on the membrane are driven through the membrane by application of heat. Analytes may be analyzed by either resonance enhanced multiphoton ionization (REMPI) or single photon ionization (SPI), both of which are provided in the apparatus and can be selected as alternative sources.
    Type: Grant
    Filed: April 20, 2005
    Date of Patent: January 9, 2007
    Assignee: SRI International
    Inventors: Harald Oser, Michael J. Coggiola, Steven E. Young, Grace F. Chou
  • Direct liquid injection inlet to a laser photoionization apparatus
    Patent number: 7095016
    Abstract: A method and apparatus are provided for analyzing an analyte at low concentration in a liquid sample by photoionization and mass spectrometry. An inlet system is provided for direct injection of the liquid sample using a capillary tube. The method and apparatus allow for 20 to 2000-fold improvement of the lower detection limit of an analyte in a liquid sample compared to a conventional liquid chromatography/mass spectrometer apparatus.
    Type: Grant
    Filed: April 29, 2004
    Date of Patent: August 22, 2006
    Assignee: SRI International
    Inventors: Harald Oser, Michael J. Coggiola, Steven E. Young, David R. Crosley
  • Direct liquid injection inlet to a laser photoionization apparatus
    Publication number: 20040222373
    Abstract: A method and apparatus are provided for analyzing an analyte at low concentration in a liquid sample by photoionization and mass spectrometry. An inlet system is provided for direct injection of the liquid sample using a capillary tube. The method and apparatus allow for 20 to 2000-fold improvement of the lower detection limit of an analyte in a liquid sample compared to a conventional liquid chromatography/mass spectrometer apparatus.
    Type: Application
    Filed: April 29, 2004
    Publication date: November 11, 2004
    Applicant: SRI International
    Inventors: Harald Oser, Michael J. Coggiola, Steven E. Young, David R. Crosley